Tirzepatide: all 180 studies that test it

Page 1 of 2. Open to participants first (96), then studies with results posted, then the rest; newest registration first within each.

• A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 DiabetesNot yet recruitingNCT07881458Phase 3
• A Study of EloraTZP in Adult Participants With Obesity Without Type 2 DiabetesNot yet recruitingNCT07881432Phase 3
• PROACT AYA: Preventing Overweight/Obesity-Associated Cardiotoxicity With Tirzepatide In Adolescent And Young Adult Cancer Survivors - A Phase 2 Single-Arm, Single-Center Feasibility StudyRecruitingNCT07874828Phase 2
• A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide MedicationRecruitingNCT07868354Phase 1
• Trial of Innovative Fat-loss Focused Approaches in Patients With Class I Obesity: a Comparative StudyRecruitingNCT07866183Not applicable
• Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea: A Randomised Comparative Effectiveness TrialNot yet recruitingNCT07846865Phase 2/3
• Efficacy of Tirzepatide for Weight Management in Patients With Suboptimal Weight Loss After Bariatric Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical TrialNot yet recruitingNCT07829198Phase 3
• Randomized Controlled Trial of Tirzepatide for Methamphetamine Use DisorderNot yet recruitingNCT07825857Phase 2
• Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)RecruitingNCT07817875Phase 3
• Tirzepatide and Levonorgestrel IUD Therapy for EIN and Early-Stage Endometrial CancerNot yet recruitingNCT07812636Early Phase 1
• A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or ObesityRecruitingNCT07803744Phase 1
• Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving LorlatinibNot yet recruitingNCT07782359Phase 1
• GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPDNot yet recruitingNCT07747805Phase 2
• Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With ObesityNot yet recruitingNCT07738276Phase 3
• Tirzepatide for Treatment of CCCARecruitingNCT07734870Phase 2
• Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized TrialNot yet recruitingNCT07734792Phase 2/3
• Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese PatientsNot yet recruitingNCT07715929Phase 4
• Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIVEnrolling by invitationNCT07707778Phase 4
• Effect of Tirzepatide on Diabetic Peripheral Sensorimotor NeuropathyNot yet recruitingNCT07706088Phase 4
• An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use DisorderEnrolling by invitationNCT07693608Phase 2
• Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA TrialNot yet recruitingNCT07676331Phase 2
• Tirzepatide in the Treatment of Cannabis Use DisorderNot yet recruitingNCT07671248Phase 3
• Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEFNot yet recruitingNCT07630454Phase 4
• Tirzepatide in the Treatment of Endometrial CancerNot yet recruitingNCT07605247Phase 2
• Multi-Site Trial of Tirzepatide for Smoking CessationRecruitingNCT07602699Phase 2
• Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.RecruitingNCT07588438Phase 4
• Tirzepatide Titration to Reduce Side Effects in Individuals With ObesityRecruitingNCT07574723Not applicable
• Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol SecretionRecruitingNCT07573163Phase 2
• Incretin Therapies in Obesity-related HFpEFRecruitingNCT07554638Phase 4
• A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLDRecruitingNCT07527910Phase 2
• DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot StudiesNot yet recruitingNCT07483801Phase 4
• Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo in Participants Who Are Either Obese or Overweight With Weight-Related Comorbidities (SURMOUNT-1)RecruitingNCT07481747Phase 3
• Trial of Tirzepatide for the Treatment of Cannabis Use DisorderNot yet recruitingNCT07468552Phase 2
• A Study to Evaluate ALN-2232 in Participants With ObesityRecruitingNCT07463846Phase 1/2
• Combination of Biologic and Anti-obesity Therapies in Psoriatic ArthritisRecruitingNCT07443956Not applicable
• Tirzepatide (Spartina) in Obese Kidney Transplant RecipientsRecruitingNCT07423247Phase 4
• Tirzepatide and Muscle Outcomes in ObesityRecruitingNCT07373834Not applicable
• A Trial Within Cohort Feasibility Study Design Comparing Standard of Care Versus Weight Loss (Achieved Through Tirzepatide) for Obesity-related Hypertension in Young AdultsRecruitingNCT07364175Not applicable
• A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial CancerNot yet recruitingNCT07349641Phase 2
• Effect of Semaglutide and Tirzepatide Combined With Exercise in ObesityNot yet recruitingNCT07319975Not applicable
• Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With ObesityRecruitingNCT07293325Not applicable
• Tirzepatide Combined With Cognitive-Behavioural Therapy (CBT) for Adults With Alcohol Use Disorder (AUD) and Overweight/Obesity (OOB)Not yet recruitingNCT07292519Phase 2
• A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood SugarRecruitingNCT07284511Phase 2/3
• Tirzepatide for the Treatment of Cannabis Use DisorderNot yet recruitingNCT07265752Phase 2
• Tirzepatide's Role in Postmenopausal HR+ Breast Cancer SurvivorsRecruitingNCT07257484Phase 4
• A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)RecruitingNCT07247084Phase 4
• Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and ObesityRecruitingNCT07245771Phase 1/2
• Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With ObesityRecruitingNCT07228741Phase 2
• Tirzepatide to Slow Biological AgingRecruitingNCT07220473Phase 2
• The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With ObesityRecruitingNCT07218445Phase 4
• Tirzepatide in Idiopathic Intracranial Hypertension TrialRecruitingNCT07191873Phase 4
• Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm HealthNot yet recruitingNCT07179120Phase 2
• Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney FailureNot yet recruitingNCT07176663Not applicable
• A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)RecruitingNCT07165028Phase 3
• GLP-1R Actions on Muscle and the SkeletonRecruitingNCT07154719Phase 4
• Tirzepatide Use in People With Obesity and Type 1 DiabetesRecruitingNCT07096908Phase 4
• Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal TumorsRecruitingNCT07095517Phase 1
• Tirzepatide for Partial Lipodystrophy Treatment: A New Horizon in 2024RecruitingNCT07091734Phase 2
• Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial CancerNot yet recruitingNCT07078838Phase 2
• Tirzepatide in Obesity-Driven Endometrial CancerRecruitingNCT07065552Early Phase 1
• Tirzepatide in MetALDRecruitingNCT07046819Phase 2
• Tirzepatide for Alcohol Use DisorderRecruitingNCT06994338Phase 2
• Moving Beyond Inflammation as a Therapeutic Target for Crohn's DiseaseRecruitingNCT06976853Phase 2
• Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use DisorderRecruitingNCT06939088Phase 2
• Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or OverweightRecruitingNCT06937099Phase 3
• Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b StudyRecruitingNCT06937086Phase 3
• Effect of Tirzepatide on Markers of MASLD in Patients With ObesityRecruitingNCT06934642Early Phase 1
• Tirzepatide in PWS, HO and GNSORecruitingNCT06901245Phase 4
• A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)RecruitingNCT06857942Phase 4
• Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating DisorderRecruitingNCT06847399Phase 2
• Acute Metabolic Effects of Tirzepatide in Type 1 DiabetesRecruitingNCT06820281Phase 2
• Effects of Tirzepatide on Muscle and Vascular Health in Obese Older AdultsRecruitingNCT06811324Phase 2
• TIRzepatide for the Treatment of Obesity in Patients With Atrial FibrillationRecruitingNCT06802081Phase 2
• Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) PatientsRecruitingNCT06774079Phase 4
• Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility StudyRecruitingNCT06759701Early Phase 1
• Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or ObeseNot yet recruitingNCT06732245Phase 2
• Study of Tirzepatide for Recovery and Alcohol Use ManagementRecruitingNCT06727331Phase 2
• 2024 Tirzepatide-Bariatric SurgeryRecruitingNCT06721507Phase 4
• A First-In-Human Study of ARO-INHBE in Adults With Obesity With and Without Type 2 Diabetes MellitusRecruitingNCT06700538Phase 1/2
• Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or TirzepatideRecruitingNCT06657209Phase 4
• Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use DisorderRecruitingNCT06651177Phase 2
• GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 DiabetesRecruitingNCT06630585Phase 3
• The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery DiseaseRecruitingNCT06606821Phase 4
• Glucagon-Like Peptide-1 Receptor Agonist in ADPKDRecruitingNCT06582875Phase 2
• Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast CancerRecruitingNCT06518837Phase 2
• Tirzepatide Weight Loss for MRD+ Early Breast CancerRecruitingNCT06517212Phase 2
• A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)RecruitingNCT06439277Phase 3
• Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis SuppurativaNot yet recruitingNCT06301256Not applicable
• Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset DiabetesRecruitingNCT06246799Phase 3
• Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or ObesityNot yet recruitingNCT06180616Phase 2
• A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or OverweightRecruitingNCT06143956Phase 2
• Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With ObesityRecruitingNCT05933499Phase 2
• Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/ObesityRecruitingNCT05912621Phase 2
• Effect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCTRecruitingNCT05708859Phase 4
• Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1RecruitingNCT05659368Phase 2
• Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 DiabetesRecruitingNCT05553093Phase 4
• Holding vs. Continuing Incretin-based Therapies Before Upper EndoscopyCompletedNCT06533527Phase 4Results posted
• A Study of Tirzepatide (LY3298176) in Healthy Lactating FemalesCompletedNCT05978713Phase 1Results posted
• A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes (SURPASS-CN-MONO)CompletedNCT05963022Phase 3Results posted
• A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related ComorbiditiesCompletedNCT05822830Phase 3Results posted

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