Sirolimus: all 520 studies that test it
Page 4 of 6. Open to participants first (86), then studies with results posted, then the rest; newest registration first within each.
- Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous MalformationStatus unknownNCT03767660Phase 4
- Bioequivalence Study of NPC-12 (Sirolimus) Granules and TabletsCompletedNCT03765944Phase 1
- Study of Sirolimus in CTD-TP in ChinaStatus unknownNCT03688191Phase 4
- Study of Sirolimus in Patients With Advanced Pancreatic CancerStatus unknownNCT03662412Phase 1/2
- CD40-L Blockade for Prevention of Acute Graft-Versus-Host DiseaseCompletedNCT03605927Phase 1
- Efficacy and Safety of Sirolimus to Vascular AnomaliesCompletedNCT03583307Not applicable
- Sirolimus vs Mycophenolate With Tacrolimus in Simultaneous Pancreas and Kidney TransplantationCompletedNCT03582878Phase 4
- Tolerance by Engaging Antigen During Cellular HomeostasisCompletedNCT03504241Phase 1
- Sirolimus-based Immunosuppression Treatment Regimen for Liver TransplantationStatus unknownNCT03500848Phase 2/3
- Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and LeiomyomatosisStatus unknownNCT03500367Phase 4
- Stem Cell Transplant in Patients With Severe Sickle Cell DiseaseTerminatedNCT03421756Early Phase 1
- Rapamycin Treatment for Activated Phosphoinositide 3-Kinase δ SyndromeCompletedNCT03383380Phase 1/2
- A Pilot-Study of Sirolimus for the Treatment of Systemic SclerosisStatus unknownNCT03365869Phase 2
- Sirolimus Treatment for Refractory PRCACompletedNCT03364764Phase 4
- Rapamycin Treatment for ALSCompletedNCT03359538Phase 2
- Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder CancerWithdrawnNCT03298958Phase 3
- Epacadostat (INCB24360) in Combination With Sirolimus in Advanced MalignancyActive, not recruitingNCT03217669Phase 1
- Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation FailureCompletedNCT03161340Phase 2
- Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease TrialActive, not recruitingNCT03150914Phase 3
- Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous SclerosisCompletedNCT03140449Phase 3
- Novel Compositions for Treating or Preventing Dermal DisordersCompletedNCT03103893Phase 1/2
- Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy VolunteersCompletedNCT03072485Phase 1
- Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) StudyStatus unknownNCT03016715Phase 2
- Impact of Sirolimus and Maraviroc on CCR5 Expression and the HIV-1 Reservoir in HIV-infected Kidney Transplant RecipientsWithdrawnNCT02990312Phase 4
- Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal CancerWithdrawnNCT02833506Phase 1
- Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and ChondrosarcomaCompletedNCT02821507Phase 2
- Omental Islet TransplantCompletedNCT02821026Phase 1/2
- Monotherapy With Rapamycin in Long-standing Type 1 DiabetesCompletedNCT02803892Phase 2
- A Study of Rapamycin Combined With Intravesical BCG in Patients With Non-muscle Invasive Bladder CancerCompletedNCT02753309Early Phase 1
- Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCTTerminatedNCT02728700Phase 1
- Adjuvant Anti-Recurrence Treatment With Rapamycin on Early-stage HCCCompletedNCT02724332Phase 1
- Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid TumorsCompletedNCT02688881Phase 4
- Study Comparing Efficacy and Safety of Mycophenolate Mofetil (Cellcept) With Delayed Introduction of Sirolimus and Discontinuation of Cyclosporine, With Those of Mycophenolate Mofetil and Long Term Continuation of Cyclosporine in Renal Transplant RecipientsCompletedNCT02686619Phase 3
- Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant PatientsCompletedNCT02683291Phase 4
- Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell DiseaseTerminatedNCT02678143Phase 1
- To Evaluate the Efficacy and Safety of Rapamycin for Crohn's Disease-related StrictureStatus unknownNCT02675153Not applicable
- Conversion to Sirolimus: Effects in Cytomegalovirus Infection RecurrenceStatus unknownNCT02671318Phase 4
- High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous DiseaseActive, not recruitingNCT02629120Phase 1/2
- Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade PineoblastomaCompletedNCT02596828Phase 2
- Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS TumorsActive, not recruitingNCT02574728Phase 2
- Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With MyelofibrosisWithdrawnNCT02528877Phase 1
- Sirolimus for the Treatment of HyperinsulinismWithdrawnNCT02524639Phase 1/2
- suPERficial Slow-flow Vascular malFORMations Treated With sirolimUSCompletedNCT02509468Phase 2
- Minimal Islet Transplant at Diabetes OnsetCompletedNCT02505893Phase 2
- Rapamycine vs Placebo for the Treatment of Inclusion Body MyositisCompletedNCT02481453Phase 2/3
- The Pilot Study Evaluate the Safety and Efficacy of Sirolimus in Patients With PIK3CA Mutation and/or PIK3CA Amplification Refractory Solid TumorsCompletedNCT02449564Not applicable
- Sirolimus Effect on Hypertrophic Syndromes Related Gene PIK3CACompletedNCT02443818Phase 2
- Trial With Gemcitabine and Rapamycin in Second Line of Metastatic OsteosarcomaCompletedNCT02429973Phase 2
- Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent PlacementWithdrawnNCT02365415Phase 2
- Bioavailability Study of Sirolimus Tablets 2 mg Under Fed ConditionCompletedNCT02296762Phase 1
- Bioavailability Study of Sirolimus Tablets 2 mg Under Fasting ConditionCompletedNCT02296749Phase 1
- Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical SirolimusTerminatedNCT02214706Not applicable
- Effects of the Quadruple Immunosuppression on Peripheral Blood Lymphocytes and Development of Anti-HLA Antibodies in Kidney TransplantStatus unknownNCT02208791Phase 4
- Sirolimus Prophylaxis for aGVHD in TME SCIDWithdrawnNCT02177760Phase 2
- Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung CancerWithdrawnNCT02126527Phase 1
- Calcineurin Inhibitor Based Immunosuppression WithdrawalCompletedNCT02117596Not applicable
- Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber SyndromeCompletedNCT02080624Phase 2
- Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney DiseaseStatus unknownNCT02055079Phase 3
- Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&SirolimusCompletedNCT01958190Phase 4
- Cardiac Allograft Remodeling and Effects of SirolimusTerminatedNCT01889992Phase 1
- Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or SurgeryCompletedNCT01888302Phase 1
- Tuberous Sclerosis Complex: Facial Angiofibroma Skin CreamCompletedNCT01853423Phase 1
- Therapeutic Efficacy of Topical Sirolimus in Early Stage Cutaneous T-cell Lymphoma (CTCL)WithdrawnNCT01843998Phase 2
- Neoadjuvant Rapamycin in Patients Undergoing Radical CystectomyCompletedNCT01827618Early Phase 1
- Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01822015Early Phase 1
- Sirolimus for Eosinophil-Associated Gastrointestinal DisordersTerminatedNCT01814059Phase 1
- Efficacy and Safety of the Mammalian Target of Rapamycin (mTor Rapamycin) Inhibitor in Vascular MalformationsCompletedNCT01811667Phase 3
- A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy SubjectsCompletedNCT01809860Phase 1
- Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive ProtocolTerminatedNCT01797315Phase 4
- Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By SurgeryCompletedNCT01791088Phase 1
- The Biomarker for Immunosuppressive Agents Metabolism in Chinese Renal Transplant RecipientsStatus unknownNCT01699360Phase 4
- Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT01689987Phase 1
- Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue SarcomaCompletedNCT01684449Phase 1/2
- Sirolimus for Massive Polycystic LiverStatus unknownNCT01680250Phase 2/3
- Intravitreal Injections of Sirolimus in the Treatment of Geographic AtrophyTerminatedNCT01675947Phase 2
- Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid TumorsCompletedNCT01670175Phase 1
- Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/LymphomaTerminatedNCT01658007Early Phase 1
- Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) TrialCompletedNCT01649960Phase 1
- The Vienna RAP Pilot StudyCompletedNCT01632605Not applicable
- Rapamune Improves Outcomes of Severe H1N1 PneumoniaCompletedNCT01620307Phase 2
- Sirolimus Use in Angioplasty for Vascular Access ExtensionCompletedNCT01595841Phase 2
- Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant RecipientStatus unknownNCT01592253Not applicable
- Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By SurgeryCompletedNCT01537107Phase 1
- Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity CancerCompletedNCT01536054Phase 1
- Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid TumorsCompletedNCT01522820Phase 1
- Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)Active, not recruitingNCT01499888Phase 1/2
- Kidney Allograft Dysfunction Without Reversible CausesWithdrawnNCT01492894Phase 4
- Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell TransplantsTerminatedNCT01488253Phase 2
- Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk NeuroblastomaCompletedNCT01467986Phase 2
- Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)CompletedNCT01462006Not applicable
- Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis RegimensActive, not recruitingNCT01428973Phase 2
- Cyclophosphamide and Pulse Dexamethasone With Rapamycin or HydroxychloroquineCompletedNCT01396200Early Phase 1
- Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung CancerWithdrawnNCT01383668Phase 1
- Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)CompletedNCT01374750Phase 2
- A Study Looking at Kidney Function in Kidney Transplant Recipients Who Are Taking Anti-rejection Medication Including Tacrolimus and With or Without Sirolimus.CompletedNCT01363752Phase 4
- Aflac ST0901 CHOANOME - Sirolimus in Solid TumorsCompletedNCT01331135Phase 1
- Strategies To Prevent Cardiac Allograft Vasculopathy Related Events in Heart Transplant RecipientsWithdrawnNCT01305395Not applicable
- Sirolimus or Vorinostat and Hydroxychloroquine in Advanced CancerCompletedNCT01266057Phase 1
- Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal InsufficiencyTerminatedNCT01223755Phase 2/3
- Rapamycin In Angiomyolipomas In Patients With Tuberous SclerosisCompletedNCT01217125Phase 4