Sirolimus: all 520 studies that test it
Page 5 of 6. Open to participants first (86), then studies with results posted, then the rest; newest registration first within each.
- An Open, Single Centre, Randomised, Parallel Group Study to Investigate Three Different Immunosuppressive RegimensCompletedNCT01183247Phase 4
- Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS TumoursCompletedNCT01135563Phase 1
- Lapatinib With Sirolimus or MetforminCompletedNCT01087983Phase 1
- Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced CancerActive, not recruitingNCT01087554Phase 1
- Pre Transplant Rapamycin Treatment in Islet Transplantation AloneCompletedNCT01060605Phase 3
- Docetaxel and Sirolimus in Patients With Advanced MalignanciesCompletedNCT01054313Phase 1
- Comparison of Tacrolimus and Myfortic Versus Tacrolimus and SirolimusWithdrawnNCT01038505Phase 4
- Effect of Rapamycin on Tolerance-related Biomarkers on Stable Liver Transplant RecipientsStatus unknownNCT01034345Phase 2
- Rapamycin and Regulatory T Cells in Kidney TransplantationCompletedNCT01014234Phase 2
- Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant RecipientsStatus unknownNCT00999258Phase 4
- Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell TransplantationCompletedNCT00993343Phase 3
- Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)WithdrawnNCT00957320Phase 1
- Sirolimus and Cetuximab in Advanced MalignanciesCompletedNCT00940381Phase 1
- Topical Rapamycin for FibrofolliculomasCompletedNCT00928798Phase 3
- Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate CancerWithdrawnNCT00922129Phase 2/3
- Tarceva/Rapamycin for Children With Low-grade Gliomas With or Without Neurofibromatosis Type 1 (NF1)CompletedNCT00901849Phase 1
- Nutritional and Contractile Regulation of Muscle GrowthCompletedNCT00891696Phase 1
- Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.CompletedNCT00890500Phase 1
- Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior UveitiCompletedNCT00876434Phase 1
- Rapamycin in Relapsed Acute Lymphoblastic LeukemiaCompletedNCT00874562Phase 1
- A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00861874Phase 1
- Oral Sirolimus for In-Stent RestenosisCompletedNCT00859183Phase 4
- Vandetanib and Sirolimus in Patients With Recurrent GlioblastomaCompletedNCT00821080Phase 1
- A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) ModelCompletedNCT00814944Phase 2
- Calcineurin Free Immunosuppression in Renal Transplant RecipientsCompletedNCT00812123Phase 4
- Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney TransplantationTerminatedNCT00811915Phase 3
- Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid MalignanciesTerminatedNCT00776373Phase 1/2
- Safety of Immunosuppression Minimization in Children and Adolescents After Kidney TransplantationCompletedNCT00768729Phase 1
- Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular DegenerationTerminatedNCT00766337Phase 2
- Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular DegenerationTerminatedNCT00712491Phase 1/2
- Study of Rapamycin Plus Ketoconazole in Advanced CancersCompletedNCT00708591Phase 1
- Rapamycin in Advanced CancersCompletedNCT00707135Phase 1
- A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus CorticosteroidsStatus unknownNCT00693446Phase 4
- Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney TransplantationCompletedNCT00681213Phase 4
- A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) TransplantationCompletedNCT00670423Phase 1
- Rapamycin Plus Bevacizumab in Advanced CancersCompletedNCT00667485Phase 1
- Dose Ranging Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Diabetic Macular EdemaCompletedNCT00656643Phase 2
- Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy SubjectsCompletedNCT00621101Phase 1
- Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell TransplantationCompletedNCT00612274Early Phase 1
- CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal ImpairmentCompletedNCT00604357Phase 3
- Interaction Study of Rapamycin and Sunitinib in Patients With Advanced CancersCompletedNCT00583063Early Phase 1
- Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based ImmunosuppressionCompletedNCT00555373Not applicable
- A Phase I Study of SUNITINIB and Rapamycin in Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedNCT00555256Phase 1
- Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan CriteriaStatus unknownNCT00554125Phase 3
- Proleukin and Rapamune in Type 1 DiabetesCompletedNCT00525889Phase 1
- Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant PatientsCompletedNCT00519116Phase 4
- Study Comparing Graft Function in Renal Allograft Recepients Receiving Reduced or Standard Dose CsA With SirolimusCompletedNCT00518375Phase 4
- Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft RecipientsCompletedNCT00518271Phase 2
- Phase 1 Study With Sorafenib and SirolimusCompletedNCT00509613Phase 1
- Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant GliomaCompletedNCT00509431Phase 1
- Study Evaluating the Efficacy and Safety of Cyclosporine Reduction in Kidney Transplant Recipients Receiving SirolimusCompletedNCT00507793Phase 4
- Fibrosis in Renal AllograftsStatus unknownNCT00493194Phase 4
- Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and SafetyCompletedNCT00491517Phase 2
- Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAMStatus unknownNCT00490789Phase 2
- Anti-Third Party T Lymphocytes With Nonmyeloablative Stem Cell Transplantation for Indolent Lymphoid MalignanciesTerminatedNCT00473551Phase 1
- Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant RecipientsCompletedNCT00470665Phase 3
- B-Lymphocyte Immunotherapy in Islet TransplantationTerminatedNCT00468442Phase 2
- Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT00467194Phase 1
- Strategies to Improve Islet SurvivalCompletedNCT00464555Phase 2
- Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAMCompletedNCT00457808Phase 2
- Sirolimus in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00450320Phase 1
- Drug Interaction Study of Sorafenib and Rapamycin in Advanced MalignanciesCompletedNCT00449280Phase 1
- Islet Transplantation in Type 1 DiabetesCompletedNCT00434811Phase 3
- Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy ParticipantsCompletedNCT00433485Phase 1
- Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant RecipientsCompletedNCT00428064Phase 3
- Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum CancerCompletedNCT00409994Phase 1/2
- Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard TherapyTerminatedNCT00402415Phase 1
- Safety and Tolerability of MS-R001 in Patients With Diabetic Macular Edema Secondary to Diabetic RetinopathyCompletedNCT00401115Phase 1
- Sirolimus Therapy for Poor Prognosis Immunoglobulin A NephropathyCompletedNCT00396721Phase 2
- Rapamycin With Grapefruit Juice for Advanced MalignanciesCompletedNCT00375245Phase 1
- Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal AllograftsCompletedNCT00374647Phase 4
- Sirolimus in Treating Patients With Metastatic or Unresectable Solid TumorsCompletedNCT00368914Phase 1
- Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular CarcinomaCompletedNCT00355862Phase 3
- Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)CompletedNCT00346918Phase 3
- A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid CancersTerminatedNCT00337376Phase 1
- Sirolimus and Cyclosporine for Treatment-Resistant Aplastic AnemiaStatus unknownNCT00319878Phase 1/2
- Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple MyelomaCompletedNCT00317798Phase 1
- Pilot Study to Investigate a Steroid Free Immunosuppressive Regimen for Renal Transplant RecipientsCompletedNCT00306397Phase 4
- Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney TransplantationCompletedNCT00305396Phase 4
- Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)Status unknownNCT00290069Phase 4
- Study Evaluating Sirolimus in the Treatment of Kidney TransplantCompletedNCT00282217Phase 4
- The Comparison of Tacrolimus and Sirolimus Immunosuppression Based Drug Regimens in Kidney Transplant RecipientsCompletedNCT00275535Phase 4
- The Comparison of Three Different Immunosuppressant Regimens in Kidney Transplant Recipients.CompletedNCT00275522Phase 4
- Study Comparing Two Sirolimus Regimens vs. Tacrolimus and Mycophenolate Mofetil Regimen in Kidney Transplant RecipientsCompletedNCT00266123Phase 4
- Study Comparing Two Immunosuppressive Regimens in De Novo Renal Allograft RecipientsCompletedNCT00261820Phase 4
- Study Evaluating Two Different Sirolimus-based Immunosuppressive Regimens in Elderly Kidney Transplant RecipientsCompletedNCT00254709Phase 4
- Use of Sirolimus vs. Tacrolimus For African-American Renal Transplant RecipientsStatus unknownNCT00252655Phase 4
- Study Comparing Cyclosporin Dose Reduction With Cyclosporin Elimination in Kidney Transplant Recipients Taking SirolimusCompletedNCT00248313Phase 3
- Rapamycin vs Methotrexate in Diffuse SScCompletedNCT00241189Phase 1/2
- Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia PatientsCompletedNCT00235560Phase 2
- Influence of Sirolimus and MMF on Vascular Function and Markers of Cellular Function in Renal Transplant RecipientsCompletedNCT00204321Phase 4
- Study Evaluating Sirolimus in Kidney Transplant Recipients in IndiaCompletedNCT00195481Phase 4
- Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney TransplantCompletedNCT00188955Phase 4
- Comparison of Sirolimus to Tacrolimus for Long Term Therapy in Kidney Transplant With no SteroidsCompletedNCT00170053Phase 1
- Study Evaluating Sirolimus in Kidney Transplant Recipients.CompletedNCT00167947Phase 3
- Sirolimus Blood Concentrations on Conversion From Oral Solution to TabletsStatus unknownNCT00166842Phase 4
- The Effect of Sirolimus on the Pharmacokinetics of TacrolimusStatus unknownNCT00166829Phase 4
- The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant PatientsStatus unknownNCT00166816Phase 4
- Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell TransplantationCompletedNCT00146614Phase 2
- Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell TransplantationCompletedNCT00144703Phase 2