Protein Kinase Inhibitors: all 15,278 studies that test it

Page 54 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.

• Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2CompletedNCT01419639Phase 2Results posted
• Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)TerminatedNCT01418001Phase 1/2Results posted
• Safety and PK Study of BIBF 1120 in Japanese Patients With IPF: Follow up Study From 1199.31(NCT01136174)CompletedNCT01417156Phase 2Results posted
• Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck LesionsCompletedNCT01414426Phase 2Results posted
• AC220 for Children With Relapsed/Refractory ALL or AMLCompletedNCT01411267Phase 1Results posted
• Efficacy Regarding Renal Function of Everolimus in Combination With Specific Standard Immunosuppressive Regimen Lung Transplant RecipientsCompletedNCT01404325Phase 3Results posted
• Intercalating and Maintenance Use of Iressa Versus Chemotherapy in Selected Advanced Non Small Cell Lung CancerCompletedNCT01404260Phase 3Results posted
• Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform NeurofibromasTerminatedNCT01402817Phase 2Results posted
• Ph I Ipilimumab Vemurafenib Combo in Patients With v-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF)TerminatedNCT01400451Phase 1Results posted
• Everolimus and Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma (RCC)CompletedNCT01399918Phase 2Results posted
• A Relative Bioavailability and Food Effect Study of New FormulationsCompletedNCT01398475Phase 1Results posted
• MLN8237 in Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma Treated With Rituximab +/- VincristineCompletedNCT01397825Phase 1/2Results posted
• Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)CompletedNCT01397448Phase 2/3Results posted
• Drug Interaction Study With Rifampicin and AfatinibCompletedNCT01396265Phase 1Results posted
• A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal TumorCompletedNCT01396148Phase 2Results posted
• Erlotinib Plus Tivantinib (ARQ 197) Versus Single Agent Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung CancerCompletedNCT01395758Phase 2Results posted
• Lapatinib With Carboplatin and Paclitaxel in Esophagus and Gastroesophageal Junction (GEJ)TerminatedNCT01395537Phase 1/2Results posted
• Dasatinib Added to Gemcitabine for Subjects With Locally-advanced Pancreatic CancerCompletedNCT01395017Phase 2Results posted
• Neo-adjuvant Therapy With Anastrozole Plus Pazopanib in Stage II and III ER+ Breast CancerTerminatedNCT01394211Phase 2Results posted
• A Phase 1 Study of LY2835219 In Participants With Advanced CancerCompletedNCT01394016Phase 1Results posted
• A Study of LY2584702 in Participants With Advanced CancerTerminatedNCT01394003Phase 1Results posted
• A Study of LY2228820 in Participants With Advanced CancerCompletedNCT01393990Phase 1Results posted
• The Safety And Efficacy Of Maintenance Therapy With CP-690,550CompletedNCT01393899Phase 2Results posted
• A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's DiseaseCompletedNCT01393626Phase 2Results posted
• Safety and Efficacy of Idelalisib in Relapsed or Refractory Hodgkin LymphomaCompletedNCT01393106Phase 2Results posted
• Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)TerminatedNCT01392495Phase 3Results posted
• Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension ParticipantsCompletedNCT01392469Phase 3Results posted
• Asian Phase II Study of INC424 in Patients With Primary Myelofibrosis (MF), Post-PV MF or Post-ET MFCompletedNCT01392443Phase 2Results posted
• Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)CompletedNCT01392183Phase 2Results posted
• Sunitinib or Cediranib for Alveolar Soft Part SarcomaCompletedNCT01391962Phase 2Results posted
• Pazopanib in Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors (GIST)TerminatedNCT01391611Phase 2Results posted
• Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid TumorsCompletedNCT01390818Phase 1Results posted
• A Drug Interaction Study to Assess the Effect of LY317615 on the Metabolic Pathway of WarfarinCompletedNCT01388335Phase 1Results posted
• BKM120 in Metastatic Castration-resistant Prostate CancerTerminatedNCT01385293Phase 2Results posted
• Axitinib Before Surgery in Treating Patients With High-Risk Prostate CancerCompletedNCT01385059Phase 2Results posted
• Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic LeukemiaTerminatedNCT01383447Phase 1/2Results posted
• Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in BladderTerminatedNCT01382706Phase 2Results posted
• Bortezomib, Rituximab, and Dexamethasone With or Without Temsirolimus in Treating Patients With Untreated or Relapsed Waldenstrom Macroglobulinemia or Relapsed or Refractory Mantle Cell or Follicular LymphomaCompletedNCT01381692Phase 1/2Results posted
• BIBF 1120 for Recurrent High-Grade GliomasCompletedNCT01380782Phase 2Results posted
• Pharmacokinetics of Ridaforolimus (MK-8669) in Chinese Participants (MK-8669-059)CompletedNCT01380184Phase 1Results posted
• A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial CancerCompletedNCT01379534Phase 2Results posted
• Safety and Efficacy of RAD001 + TACE in Localized Unresectable HCCTerminatedNCT01379521Phase 2Results posted
• A Study of Vemurafenib in Metastatic Melanoma Participants With Brain MetastasesCompletedNCT01378975Phase 2Results posted
• A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TRIGGER)CompletedNCT01378962Phase 2Results posted
• Combination Trial of Pimasertib (MSC1936369B) With TemsirolimusTerminatedNCT01378377Phase 1Results posted
• GSK1120212 Rollover StudyTerminatedNCT01376310Phase 2Results posted
• Ruxolitinib and Lenalidomide for Patients With MyelofibrosisCompletedNCT01375140Phase 2Results posted
• Efficacy of Everolimus Alone or in Combination With Pasireotide LAR in Advanced PNETTerminatedNCT01374451Phase 2Results posted
• A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic CancerCompletedNCT01373164Phase 1/2Results posted
• Vandetanib to Treat Advanced Kidney CancerTerminatedNCT01372813Phase 2Results posted
• A Study of Tarceva (Erlotinib) in Patients With Locally Advanced, Metastatic or Recurrent Non-Small Cell Cancer Who Present Epidermal Growth Factor Receptor MutationsCompletedNCT01372384Phase 2Results posted
• Single Dose Study in Healthy Participants to Investigate the Safety and Absorption of LY2584702CompletedNCT01372085Phase 1Results posted
• Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01371981Phase 3Results posted
• Akt Inhibitor MK2206, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedNCT01369849Phase 1/2Results posted
• A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib ProtocolsTerminatedNCT01369433Not applicableResults posted
• Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGFTerminatedNCT01367275Phase 2Results posted
• Linifanib in Treating Patients With Advanced, Refractory Colorectal CancerTerminatedNCT01365910Phase 2Results posted
• Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)TerminatedNCT01365468Phase 2Results posted
• 12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD)TerminatedNCT01362348Phase 2Results posted
• An Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung CancerCompletedNCT01362296Phase 2Results posted
• Neoadjuvant Pazopanib in Renal Cell CarcinomaCompletedNCT01361113Phase 2Results posted
• ARCHER 1009 : A Study Of Dacomitinib (PF-00299804) Vs. Erlotinib In The Treatment Of Advanced Non-Small Cell Lung CancerCompletedNCT01360554Phase 3Results posted
• A Study To Assess the Immune Response Following Administration Of Influenza and Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving CP-690,550 Or PlaceboCompletedNCT01359150Phase 2Results posted
• A Drug Interaction Study to Assess the Effect of LY2603618 on the Metabolic Pathway of DesipramineCompletedNCT01358968Phase 1Results posted
• A Study of the Safety, Tolerability, and Efficacy of MK-8353 in Participants With Advanced Solid Tumors (MK-8353-001)TerminatedNCT01358331Phase 1Results posted
• Study Assessing Double-masked Uveitis TreatmentCompletedNCT01358266Phase 3Results posted
• A Study of Adavosertib (MK-1775) in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone for Participants With Platinum-Sensitive Ovarian Tumors With the P53 Gene Mutation (MK-1775-004)CompletedNCT01357161Phase 2Results posted
• A Clinical Research Study to Determine Whether PD 0332991 May Be Effective in Treating Patients With Liver CancerCompletedNCT01356628Phase 2Results posted
• E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With Advanced or Metastatic Solid Tumors and Previously Untreated Gastric CancerTerminatedNCT01355302Phase 1/2Results posted
• Dose Escalation Study of MLN0128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid MalignanciesCompletedNCT01351350Phase 1Results posted
• Erlotinib and Docetaxel in Second Line of Treatment in Patients With Non Small Cell Lung CancerCompletedNCT01350817Phase 2Results posted
• Alvocidib, Cytarabine, and Mitoxantrone Hydrochloride or Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01349972Phase 2Results posted
• Akt Inhibitor MK2206 in Treating Patients With Recurrent or Metastatic Head and Neck CancerCompletedNCT01349933Phase 2Results posted
• Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma MultiformeCompletedNCT01349660Phase 1/2Results posted
• Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)CompletedNCT01349049Phase 1/2Results posted
• A Phase 2 Study of PLX3397 in Patients With Recurrent GlioblastomaTerminatedNCT01349036Phase 2Results posted
• Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF)CompletedNCT01348490Phase 2Results posted
• Cabozantinib (XL184) in Men With Castrate-Resistant Prostate CancerCompletedNCT01347788Phase 1Results posted
• A Phase I/II Study of Continuous Oral Treatment With BIBF 1120 Added to Standard Gemcitabine/Cisplatin Therapy in First Line NSCLC Patients With Squamous Cell Histology.CompletedNCT01346540Phase 1Results posted
• LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based ChemotherapyCompletedNCT01345682Phase 3Results posted
• LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapyTerminatedNCT01345669Phase 3Results posted
• A Study of Erlotinib (Tarceva) Versus Gemcitabine/Cisplatin as First-line Treatment in Patients With Non-small Cell Lung Cancer With EGFR MutationsCompletedNCT01342965Phase 3Results posted
• A Study of LY2603618 in Combination With Gemcitabine in Participants With Solid TumorsCompletedNCT01341457Phase 1Results posted
• Pazopanib Hydrochloride in Treating Patients With Advanced or Progressive Malignant Pheochromocytoma or ParagangliomaTerminatedNCT01340794Phase 2Results posted
• Study of Ruxolitinib (INCB018424) Sustained Release Formulation in Myelofibrosis PatientsCompletedNCT01340651Phase 2Results posted
• Phase II Study of BKM120 for Subjects With Recurrent GlioblastomaCompletedNCT01339052Phase 2Results posted
• Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade AstrocytomasTerminatedNCT01338857Phase 2Results posted
• Safety & Efficacy of BCT197 in Patients Undergoing Cardiac SurgeryTerminatedNCT01336959Phase 2Results posted
• Study of Selective BRAF Kinase Inhibitor Dabrafenib Monotherapy Twice Daily and in Combination With Dabrafenib Twice Daily and Trametinib Once Daily in Combination Therapy in Subjects With BRAF V600E Mutation Positive Metastatic (Stage IV) Non-small Cell Lung Cancer.CompletedNCT01336634Phase 2Results posted
• Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis Patients IICompletedNCT01335477Phase 3Results posted
• Safety and Efficacy of BIBF 1120 at High Dose in Idiopathic Pulmonary Fibrosis PatientsCompletedNCT01335464Phase 3Results posted
• A Phase II Trial of OSI-906 and Sorafenib in Advanced Hepatocellular CancerTerminatedNCT01334710Phase 2Results posted
• MK-2206 and AZD6244 in Patients With Advanced Colorectal CarcinomaCompletedNCT01333475Phase 2Results posted
• E7050 in Combination With Cetuximab Versus Cetuximab Alone in the Treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and NeckCompletedNCT01332266Phase 1/2Results posted
• Safety & Efficacy of BCT197A2201 in COPD Patients Presenting With an ExacerbationCompletedNCT01332097Phase 2Results posted
• Bosutinib in Adult Patients With Recurrent GlioblastomaCompletedNCT01331291Phase 2Results posted
• A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration Resistant Prostate CancerCompletedNCT01331083Phase 2Results posted
• Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic ChondrosarcomaCompletedNCT01330966Phase 2Results posted
• A Study in Cancer Patients to Evaluate the Effect of Lapatinib on the QTc IntervalCompletedNCT01328054Phase 4Results posted
• Safety and Efficacy Study of a BTK Inhibitor in Subjects With Relapsed or Refractory Diffuse Large B-cell LymphomaCompletedNCT01325701Phase 2Results posted

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