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Probiotic clinical trials

Also written Bio 25.

A group of medicines. Lacticaseibacillus rhamnosus GG (57 studies) is counted on its own page; this page counts the studies that name Probiotic itself.

studies test it
442
open now
79
in phase 3
31
first study started
2003

How each study uses Probiotic is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

Get an email when these change. Save the Probiotic studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

Watch these studies
See an example email

Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

One email a week for all your saved searches. Stop any time.

Approvals

The first approval found in each region, with its record

United States
Not in FDA's approval records
European Union
Not in EMA's list of EU-wide authorisations

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Name

Probiotic
328
Probiotic Supplement
21
Probiotic group
16
Probiotic capsule
9
Probiotic Arm
7

Development codes

Bio 25
2
ATCC 700396
1
HSB001
1

Medicines filed under Probiotic

As reviewed, so not every one. Each counts its studies on its own page, not here.

Lacticaseibacillus rhamnosus GG
57

Studies by the year they started

439 studies that test it; most in 2024 (55); 2 more planned to start later

Studies that test Probiotic, by start year
YearStudies
20031
20051
20062
20075
20082
20097
20105
20118
201219
201315
20149
201518
201622
201726
201821
201916
202024
202134
202229
202341
202455
202550
202629

By phase

A phase 1/2 study counts in both.

Early Phase 1
10
Phase 1
22
Phase 2
65
Phase 3
31
Phase 4
21
No phase
315

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Obesity
23
Irritable Bowel Syndrome
15
Respiratory Tract Infections
12
Constipation
8
Diarrhea
8
COVID-19
6
Periodontitis
6
Non-alcoholic Fatty Liver Disease
5
Diabetes Mellitus, Type 2
5
Attention Deficit Disorder with Hyperactivity
5
Overweight
4
Rhinitis, Allergic
4

Who runs them

Industry 160 · Other 282

Wecare Probiotics Co., Ltd. (47) · Min-Tze LIONG (12) · The Archer-Daniels-Midland Company (9) · Lallemand Health Solutions (9) · University of Copenhagen (9) · Danisco (8) · AB Biotics, SA (7) · Probi AB (7)

Often tested with

Tested in the same studies.

Prebiotics (9) · Rifaximin (2) · Zinc (2) · Omega-3 fatty acid (2) · Vitamin D (2) · Amoxicillin (2) · Fish Oils (2) · Zinc Acetate (1)

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Reaching primary completion within a year · 37

Studies that test Probiotic.

Studies

Open first, then newest update. How each study uses Probiotic is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing it · 442

See all 442 studies that test Probiotic →

Given beside what is tested · 4 — Probiotic is usual care or a partner of the new treatment
As the comparator · 7 — what is tested is compared with Probiotic

What changed recently

From the registry's own updates since Oct 15, 2026.

Started recruiting1

Stopped1

Newly registered1