Phosphodiesterase 5 Inhibitors: all 685 studies that test it
Page 5 of 7. Open to participants first (38), then studies with results posted, then the rest; newest registration first within each.
- Sildenafil Impact on Ventricular Function in Patients With Heart FailureCompletedNCT01936350Phase 2/3
- Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Udenafil and Bosentan After Oral AdministrationStatus unknownNCT01929213Phase 1
- Clinical Trial to Investigate the Pharmacokinetic Drug Interaction Between Udenafil and DapoxetineStatus unknownNCT01928563Phase 1
- Safety and Efficacy Study of HGP1207 in Patients With Pulmonary HypertensionStatus unknownNCT01913847Phase 3
- Chemoimmunotherapy and Radiation in Pancreatic CancerCompletedNCT01903083Phase 1
- Safety Study of Once-a-Day Dosing of Udenafil to Treat Erectile DysfunctionCompletedNCT01901640Phase 3
- VasoREACTivity Testing With Intravenous SILdenafil in Patients With Precapillary Pulmonary HypertensionCompletedNCT01889966Phase 4
- Sildenafil for PNTM InfectionCompletedNCT01853540Phase 1/2
- Sulindac for Patients With AMLWithdrawnNCT01843179Phase 2
- Phosphodiesterase-5 (PDE-5) Inhibition in Heart Transplant RecipientsWithdrawnNCT01812434Not applicable
- REmodelling in Diabetic CardiOmapathy: Gender Response to PDE5i InhibiTOrsCompletedNCT01803828Phase 4
- Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH.CompletedNCT01800292Phase 4
- Efficacy and Safety Study of Udenafil to Treat Erectile DysfunctionCompletedNCT01774864Phase 3
- Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance ImageStatus unknownNCT01769482Phase 4
- Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury.CompletedNCT01762475Phase 2
- Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in NewbornsCompletedNCT01757782Phase 4
- Tadalafil Effects in Left Ventricle Diastolic Dysfunction in Resistant Hypertensive PatientsCompletedNCT01743911Not applicable
- A Randomized Trial of Udenafil Therapy in Patients With Mild Pulmonary Hypertension [ULTIMATE-Mild PHT]Status unknownNCT01696240Phase 3
- Pharmacokinetics of Sildenafil in Premature InfantsCompletedNCT01670136Phase 1
- Food Effect Study For New FormulationCompletedNCT01656798Phase 1
- Vardenafil as add-on Therapy for Patients With Pulmonary Hypertension Treated With Inhaled IloprostStatus unknownNCT01649739Phase 4
- Udenafil Therapy to Improve Symptomatology, Exercise Tolerance and Hemodynamics in Patients With Chronic Systolic Heart FailureTerminatedNCT01646515Phase 3
- Urinary Biomarker Study With Sulindac and DifluoromethylornithineWithdrawnNCT01636128Phase 2
- Study to Evaluate Hemodynamic Response to to a Sublingual Dose of Glyceryl Trinitrate in Subjects Receiving TA-1790, Sildenafil Citrate, and PlaceboCompletedNCT01616485Phase 1
- Sildenafil Versus Placebo in Chronic Heart FailureStatus unknownNCT01616381Phase 3
- A Randomized Trial of Udenafil Therapy in Patients With Heart Failure With Preserved Ejection Fraction [ULTIMATE-HFpEF]Status unknownNCT01599117Phase 3
- PDE Inhibitors in DMD Study (Acute Dosing Study)CompletedNCT01580501Phase 1
- Fontan Patients: Comprehensive Evaluation of Pulmonary Circulation and Ventricular FunctionCompletedNCT01572363Not applicable
- Mycophenolate Mofetil, Carnitine and PDE5 Inhibitor, Three Potential Treatments for Resistant Proteinuria Slowing Diabetic Nephropathy DeteriorationStatus unknownNCT01566006Not applicable
- Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN)Status unknownNCT01564303Not applicable
- Sildenofil in Persistent Pulmonary Hypertension in NewbornsStatus unknownNCT01558466Phase 3
- A Trial of Tadalafil in Interstitial Lung Disease of SclerodermaCompletedNCT01553981Phase 3
- Efficacy and Safety Study of Udenafil in Patient With Pulmonary Arterial Hypertension(PAH)CompletedNCT01553721Phase 2
- Revatio Portal-Pulmonary Arterial Hypertension TrialTerminatedNCT01517854Phase 2
- Study of TARCEVA (Erlotinib) as Adjuvant Treatment for Locally Advanced Head and Neck Squamous Cell CarcinomaCompletedNCT01515137Phase 1
- Pharmacokinetics of Sildenafil Following Administration of an Chewable Tablet of Sildenafil Relative to Viagra® Conventional Oral Tablet in Healthy VolunteersCompletedNCT01514903Phase 1
- Sildenafil for Post-capillary Pulmonary Hypertension in Patients Undergoing Cardiac SurgeryCompletedNCT01481350Phase 2
- Effect of Zydena (Udenafil) on Cerebral Blood Flow and Peripheral Blood ViscosityStatus unknownNCT01466543Phase 2
- SPHERIC-1. Sildenafil and Pulmonary HypERtension In COPDStatus unknownNCT01441934Phase 3
- Lybrido for Female Sexual DysfunctionCompletedNCT01432665Phase 2
- The Efficacy of Penile Rehabilitation Using Udenafil After Total Mesorectal Excision of Rectal CancerCompletedNCT01421940Phase 4
- Role of Sildenafil Citrate in Patients With Unexplained Recurrent MiscarriagesStatus unknownNCT01419392Phase 4
- Effects of Sildenafil in Resistant Hypertensives and Genetic PolymorphismCompletedNCT01392638Not applicable
- Responsiveness of Exercise Tests in Pulmonary Arterial HypertensionCompletedNCT01391104Not applicable
- Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy PatientsStatus unknownNCT01382368Phase 4
- Doxorubicin With or Without Sildenafil, With Analysis of Cardiac MarkersCompletedNCT01375699Phase 1
- Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i TreatmentStatus unknownNCT01364701Phase 4
- The Impact of Udenafil on Exercise Capacity in Severe Chronic Obstructive Pulmonary Disease (COPD) PatientsCompletedNCT01364181Phase 3
- IV Sildenafil Persistent Pulmonary Hypertension Of The NewbornWithdrawnNCT01360671Phase 2
- Tadalafil and Sildenafil for Duchenne Muscular DystrophyCompletedNCT01359670Early Phase 1
- Effect of Modulating the nNOS System on Cardiac, Muscular and Cognitive Function in Becker Muscular Dystrophy PatientsCompletedNCT01350154Phase 2
- S0820, Adenoma and Second Primary Prevention TrialActive, not recruitingNCT01349881Phase 3
- Immunochemoradiotherapy in Patients With Pancreatic CancerCompletedNCT01342224Phase 1
- Daily Tadalafil and Gastric Emptying Time in Diabetic GastroparesisWithdrawnNCT01326117Phase 4
- A Study to Evaluate a Possible Superiority Expressed by the Faster Onset of Action and the Efficacy and Safety of Sildenafil Citrate 20mg Sublingual Tablet in the Treatment of Erectile Dysfunction of Different EtiologiesStatus unknownNCT01321489Phase 3
- On Demand Versus Daily Sildenafil for Patients Undergoing Radical ProstatectomyStatus unknownNCT01315262Phase 3
- Efficacy and Safety Study of Udenafil Tablets in Erectile Dysfunction.CompletedNCT01305083Phase 3
- Sildenafil Effect on Digital Ulcer Healing in sClerodErma SEDUCE STUDYCompletedNCT01295736Phase 3
- Effects of Vardenafil on Clinical Symptoms and Peripheral Blood Flow in Patients With Raynaud's SyndromeCompletedNCT01291199Phase 2/3
- Effect of Tadalafil on Exercise Capacity in Pediatric Fontan PatientsCompletedNCT01291069Phase 1
- The Safety of Vardenafil in Patients Undergoing Cardiac SurgeryCompletedNCT01260285Phase 1
- A Pivotal Bioequivalence Study Between The Sildenafil Powder For Oral Suspension (10 Mg/Ml) And The Sildenafil 10 Mg Immediate Release (IR) Tablet Relative To The Revatio 20 Mg IR Tablet In Healthy Volunteers Under Fasting ConditionsCompletedNCT01247805Phase 1
- A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)WithdrawnNCT01245816Phase 3
- Phase I Study to Investigate the Alcohol Interaction of DA8159CompletedNCT01241032Phase 1
- Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 DiabetesTerminatedNCT01238224Phase 1
- Clinical Study to Investigate the Safety and Pharmacokinetics of SK3530 Tablet in Renal Impaired Male PatientsCompletedNCT01232010Phase 1
- Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male PatientsCompletedNCT01231997Phase 1
- Effect of Udenafil on SpermatogenesisCompletedNCT01230541Phase 1
- Treatment of Palmar Plantar Erythrodysesthesia (PPE) With Topical SildenafilCompletedNCT01219023Phase 1
- Do Phosphodiesterase 5A Inhibitors Improve Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Pulmonary Hypertension?CompletedNCT01197469Phase 2
- Sildenafil Trial in Children and Young Adults With CFWithdrawnNCT01194232Phase 1/2
- Exercise Oscillatory Breathing and Sildenafil in Heart FailureCompletedNCT01185925Phase 2
- Efficacy and Safety of Lodenafil Carbonate in the Treatment of Erectile Dysfunction in Patients With Diabetes.CompletedNCT01180283Phase 4
- Clinical Proof-of-concept Study for the Combination BAY60-4552 / Vardenafil for the Treatment of Erectile Dysfunction Not Sufficiently Responsive to Standard Therapy With PDE5 InhibitorsCompletedNCT01168817Phase 2
- A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older VolunteersCompletedNCT01161069Phase 1
- Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart FailureCompletedNCT01156636Phase 2/3
- A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in SclerodermaCompletedNCT01117298Phase 3
- Drug Interaction Study of Avanafil and Enalapril or AmlodipineCompletedNCT01117038Phase 1
- Multiple Dose Escalation Study (14 Days) to Investigate Safety, Tolerability, PK and PD of Vardenafil and BAY60-4552CompletedNCT01110590Phase 1
- Sildenafil and Uteroplacental PerfusionStatus unknownNCT01107782Phase 2/3
- Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and TamsulosinCompletedNCT01100021Phase 1
- Assess the Effect of Food on Avanafil Pharmacokinetic (PK), to Compare 2 Oral Formulations of Avanafil,and Investigate Dose Proportionality in Healthy Male SubjectsCompletedNCT01095601Phase 1
- Study the Effect of Avanafil on the Pharmacodynamics and Pharmacokinetics of Warfarin in Healthy Male SubjectsCompletedNCT01095588Phase 1
- Sildenafil for Prevention of Cerebral VasospasmWithdrawnNCT01091870Phase 2
- Effectiveness of the Vasodilator Test With Revatio, Made in Patients With Acute Pulmonary HypertensionStatus unknownNCT01091012Phase 3
- Correlation Study of Vascular Parameters in Hypertensive Men With Erectile DysfunctionCompletedNCT01084187Phase 4
- Tadalafil in Becker Muscular DystrophyCompletedNCT01070511Phase 4
- Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) MalesCompletedNCT01067391Phase 4
- Treatment of Erectile Dysfunction - Long Term Safety and EfficacyCompletedNCT01065012Phase 3
- Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness PreventionCompletedNCT01060969Not applicable
- Study of Sildenafil Effects in Combination With Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Associated Pulmonary HypertensionCompletedNCT01055405Phase 4
- A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.CompletedNCT01054859Phase 1
- To Assess the Safety of Avanafil in Healthy and Hepatically Impaired Male Subjects.CompletedNCT01054430Phase 1
- To Compare the Pharmacokinetics of Avanafil in Subjects With Mild and Moderate Renal Impairment to Subjects With Normal Renal Function.CompletedNCT01054261Phase 1
- Early Start of Oral Sildenafil 100mg for Erectile Dysfunction After Robotic Assisted Laparoscopic Radical ProstatectomyStatus unknownNCT01054001Not applicable
- SIDAMI - Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (AMI)CompletedNCT01046838Phase 4
- A Relative Bioavailability Study of Revatio for the Crushed Tablets, Extemporaneously Prepared Formulation, and the Intact Tablets at 20 mg Dose in Healthy VolunteersCompletedNCT01027117Phase 1
- Does a Nasal Instillation of Vardenafil Normalize the Nasal Potential Difference in Cystic Fibrosis Patients?TerminatedNCT01002534Phase 2
- Chronic Sildenafil Treatment in Heart FailureCompletedNCT00975494Phase 3
- A Pharmacokinetic Study of Udenafil in Adult Subjects With or Without Impaired Hepatic FunctionCompletedNCT00956306Phase 1