Muscarinic Antagonists: all 1,070 studies that test it
Page 1 of 11. Open to participants first (106), then studies with results posted, then the rest; newest registration first within each.
- Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial FibrillationRecruitingNCT07877519Not applicable
- Early Intervention for High Risk Premyopic ChildrenNot yet recruitingNCT07863713Phase 2
- Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye DropsNot yet recruitingNCT07846787Not applicable
- PREterm Infants With Bronchial Obstruction - Prospective Study of Efficacy and Safety of Inhaled TiotropiumNot yet recruitingNCT07827859Phase 4
- Low-Dose Atropine Eye Drops for Excessive Tearing (Epiphora)RecruitingNCT07816224Phase 2
- Hyoscine Butylbromide During Transcystic Papillary Balloon Dilation for CholedocholithiasisRecruitingNCT07814976Not applicable
- Comparison of Benzhexol and Procyclidine for Tremor in Tremor-Predominant Parkinson's DiseaseRecruitingNCT07810296Not applicable
- Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)Not yet recruitingNCT07721922Phase 4
- Relapse Prevention Trial Evaluating KarXT Treatment in SchizophreniaRecruitingNCT07686263Phase 3
- Melatonin and Solifenacin for Double-J Ureteral Stent SymptomsRecruitingNCT07617922Phase 2
- Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical TrialRecruitingNCT07567040Phase 3
- 0.01% and 0.025% Atropine Eye Drops Combined Auricular Acupoint Stimulation on Myopia Control and Corneal Endothelium ChangeEnrolling by invitationNCT07537166Not applicable
- The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control GroupRecruitingNCT07456488Phase 2
- PROTECT-Study: Prospective Research on Optimizing Atropine Concentration Escalation for Children's Myopia PreventionNot yet recruitingNCT07449247Phase 1/2
- APPRAISE: Assessment of Pain and Posterior Synechiae Reduction With Atropine, an Investigation of Post-Surgical EyesRecruitingNCT07434635Phase 4
- Representation of Spatiotemporal Information in Human Episodic Memory and NavigationEnrolling by invitationNCT07423923Early Phase 1
- A PET/MRI Study of Cobenfy on Dopamine Transmission in SchizophreniaRecruitingNCT07423546Phase 1/2
- Effect of Ipratropium Bromide on EILONot yet recruitingNCT07394036Phase 2
- Study of Sacituzumab Govitecan With Atropine to Improve Tolerability in Advanced TNBC and HR+/HER2- Breast CancerNot yet recruitingNCT07367178Phase 2
- Myopia Progression Control Using Atropine 0.05% After Pediatric Cataract Surgery And Intraocular Lens Implantation SurgeryNot yet recruitingNCT07364370Not applicable
- Atropine in the Treatment of Myopia Study in MalaysiaRecruitingNCT07329777Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)RecruitingNCT07288567Phase 3
- A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum DisorderNot yet recruitingNCT07285798Phase 3
- A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With AutismNot yet recruitingNCT07284745Phase 3
- A Clinical Study to Evaluate the Efficacy and Safety of Hyoscine Butylbromide Capsules for Preoperative Preparation in Painless Gastrointestinal Endoscopy ProceduresNot yet recruitingNCT07271303Not applicable
- A Study to Evaluate the Effect of KarXT on Urological SafetyRecruitingNCT07221877Phase 4
- A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult ParticipantsRecruitingNCT07204418Phase 1
- 129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of ExacerbationRecruitingNCT07192016Phase 4
- Early-Onset Myopia Intervention ProjectRecruitingNCT07176949Not applicable
- Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic CenterNot yet recruitingNCT07164092Phase 2/3
- A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or LamotrigineRecruitingNCT07140913Phase 3
- Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting BronchodilatorsRecruitingNCT07133880Phase 4
- The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled TrialNot yet recruitingNCT07114640Phase 3
- Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism PainRecruitingNCT07109882Phase 4
- A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia ControlRecruitingNCT07095894Phase 3
- A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With SchizophreniaNot yet recruitingNCT07084831Phase 3
- A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and HyperinflationRecruitingNCT07073950Phase 4
- A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference Following Single Doses, Explore the Effect of Food After Multiple Doses of Selected Prototypes, and Evaluate Alternative Formulations of KarX and KarXT Following Single and Multiple Ascending DosesRecruitingNCT07063342Phase 1
- A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXTRecruitingNCT07061288Phase 1
- Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)RecruitingNCT07028827Phase 3
- Efficacy of Intravesical Oxybutynin in Children With Neurogenic Bladder DysfunctionRecruitingNCT07027020Phase 3
- A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's DiseaseRecruitingNCT07011745Phase 3
- A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)RecruitingNCT07011732Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's DiseaseRecruitingNCT06976216Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)RecruitingNCT06976203Phase 3
- Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled TrialRecruitingNCT06966778Not applicable
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)RecruitingNCT06951711Phase 3
- A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I DisorderRecruitingNCT06951698Phase 3
- A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)RecruitingNCT06947941Phase 3
- A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)RecruitingNCT06937229Phase 3
- A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)RecruitingNCT06929273Phase 3
- An 8-week Open-label Study of an Accelerated and Slower Switching to Xanomeline/Trospium Following Atypical Antipsychotic Treatment in Participants With SchizophreniaNot yet recruitingNCT06924255Phase 4
- An Open-Label Study to Evaluate the Efficacy and Tolerability of Xanomeline/Trospium In First Episode/Early Phase Schizophrenia PatientsNot yet recruitingNCT06923891Phase 4
- A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With SchizophreniaRecruitingNCT06882785Phase 3
- Study of Tamsulosin, Solifenacin and Mirabegron in Alleviating Ureteral Stent-related SymptomsRecruitingNCT06803030Phase 3
- Evaluating the Efficacy of the Combination of Multi-zonal Contact Lens and Atropine for Controlling Myopia ProgressionNot yet recruitingNCT06765603Phase 2
- The Effectiveness and Safety of Two Low-concentration Atropine Sulfate Eye Drops (0.01%/0.02%) for Delaying the Pediatric Myopia ProgressionRecruitingNCT06708156Phase 3
- Evaluating the Impact of Single Dose Tiotropium on Allergen-induced Early Asthmatic ResponseNot yet recruitingNCT06679465Phase 4
- A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)RecruitingNCT06585787Phase 3
- Effect of the Inhaled Triple Therapies Over the Small Airway in Biomass ExposureRecruitingNCT06571942Phase 4
- Continuation Protocol for Obstructive Sleep Apnea (OSA)Enrolling by invitationNCT06566820Phase 3
- Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral PalsyRecruitingNCT06554288Phase 1
- Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)RecruitingNCT06551246Phase 3
- Efficacy of Solifenacin or Mirabegron With Local Estrogen Versus Combination Pharmacotherapy for Overactive BladderRecruitingNCT06479720Phase 4
- The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled TrialNot yet recruitingNCT06395064Not applicable
- A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible BronchoscopyNot yet recruitingNCT06376942Phase 2/3
- Accelerating TMS for Cervical DystoniaEnrolling by invitationNCT06328114Phase 2
- A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary DiseaseRecruitingNCT06283966Phase 3
- Low Dose Atropine Eye Drops in Myopic Egyptian ChildrenNot yet recruitingNCT06265454Phase 2
- A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALSRecruitingNCT06249867Phase 2
- Efficacy of Combined Pharmacotherapy Versus Solifenacin With Vaginal Estrogen Cream for Women With Detrusor OveractivityRecruitingNCT06197295Phase 4
- A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)RecruitingNCT06126224Phase 3
- REDucing Hot FLASHes in Women Using Endocrine Therapy.RecruitingNCT06106529Phase 3
- Cycloplegic Refraction in Pediatric Patients With EsotropiaRecruitingNCT06077682Phase 4
- Effect of Hyoscine- Bromide on Duration of the First Stage of LaborRecruitingNCT06056869Not applicable
- Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic PolypectomyEnrolling by invitationNCT06041984Phase 1/2
- Electronic Spectacles Versus Low Dose Atropine in Young MyopesRecruitingNCT06034379Not applicable
- the Efficacy of 0.01% Atropine for Near Work-induced Transient Myopia and Myopic ProgressionRecruitingNCT06034366Not applicable
- Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)RecruitingNCT05980949Phase 3
- Comparisons of the Impact of Monotherapy With Mirabegron or Tolterodine Versus Combined Treatment With Mirabegron and Tolterodine on Autonomic Function and Bladder Blow Flow in Women With Overactive Bladder Syndrome: a Randomized Controlled StudyRecruitingNCT05946902Phase 4
- Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination Nebuliser Solutions in Stable Chronic Obstructive Pulmonary Disease (COPD) PatientsRecruitingNCT05890638Phase 3
- Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor PerformanceRecruitingNCT05886660Phase 2
- A Study of Atropine Sulfate in Healthy Chinese VolunteersRecruitingNCT05855018Phase 1
- Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor PerformanceRecruitingNCT05852730Phase 2
- Efficacy Comparison of 2 Low-dose Atropine Eye Drops in Vietnamese Children Myopia ManagementNot yet recruitingNCT05803863Phase 4
- A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With AsthmaRecruitingNCT05757102Phase 3
- SAINT: Safe Induction of Labor TrialRecruitingNCT05719467Phase 3
- Pharmacological Modulation of Brain Oscillations in Memory ProcessingRecruitingNCT05594017Early Phase 1
- Quinidine Versus Verapamil in Short-coupled Idiopathic Ventricular FibrillationEnrolling by invitationNCT05593757Phase 2
- Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study)RecruitingNCT05550402Not applicable
- Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin TherapyRecruitingNCT05550246Phase 1/2
- A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)RecruitingNCT05511363Phase 3
- A-eyedrops on Ocular Alignment and Binocular VisionRecruitingNCT05379855Not applicable
- TReating Incontinence for Underlying Mental and Physical HealthRecruitingNCT05362292Phase 4
- Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic AdenocarcinomaRecruitingNCT05241249Phase 2
- Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With AsthmaRecruitingNCT05222529Phase 2
- Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural PunctureRecruitingNCT05116930Phase 2
- Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect?RecruitingNCT05102396Phase 2
- Biperiden Trial for Epilepsy PreventionRecruitingNCT04945213Phase 3
- Early Oxybutinin Treatment for Boys With Posterior Urethral ValvesRecruitingNCT04526353Phase 2