Muscarinic Antagonists: all 1,032 studies that test it

Page 2 of 11. Open to participants first (107), then studies with results posted, then the rest; newest registration first within each.

• Early Oxybutinin Treatment for Boys With Posterior Urethral ValvesRecruitingNCT04526353Phase 2
• Pharmacologic Effect for Female Overactive Bladder Syndrome: Mirabegron Versus SolifenacinRecruitingNCT04023253Phase 3
• Oxybutynin for Post-surgical Bladder Pain and UrgencyRecruitingNCT03952299Phase 3
• The Effects of Bariatric Surgeries on Glucose MetabolismRecruitingNCT02823665Early Phase 1
• Study of Orphenadrine' in the Treatment of Muscle Cramps in Patients With CirrhosisRecruitingNCT02423395Phase 3
• Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer PatientsRecruitingNCT01530373Phase 2
• Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass SurgeryRecruitingNCT00992901Early Phase 1
• Study to Assess Safety and Effectiveness of Slowly Increasing Dose and Food Effect of KarXT in Participants With SchizophreniaCompletedNCT06572449Phase 3Results posted
• A Phase IIb Study of Glycopyrrolate Inhalation Solution Over 1 Week in Subjects With COPDCompletedNCT06545500Phase 2Results posted
• Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled AsthmaActive, not recruitingNCT06372496Phase 4Results posted
• Treating Respiratory Emergencies in Children StudyCompletedNCT06074185Phase 2Results posted
• A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 SchizophreniaCompletedNCT05919823Phase 3Results posted
• An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of SchizophreniaTerminatedNCT05643170Phase 3Results posted
• Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular BlockCompletedNCT05545280Phase 4Results posted
• To Evaluate Real-World Effectiveness of Fluticasone Furoate/Umeclidinium Bromide/Vilanterol (FF/UMEC/VI) in a Single Inhaler (Trelegy Ellipta) in Participants With Symptomatic COPDCompletedNCT05535972Phase 4Results posted
• Phase I Clinical Trial to Evaluate the Safety and Tolerability of Ophtalmic Solution PRO-201CompletedNCT05470881Phase 1Results posted
• Wearing-Off Period of Pharmacological Dilation and AnisocoriaCompletedNCT05238233Phase 4Results posted
• Phase 4 COPD and Suboptimal Inspiratory Flow RateCompletedNCT05165485Phase 4Results posted
• A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of SchizophreniaCompletedNCT05145413Phase 3Results posted
• Revefenacin in Chinese Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease(COPD)CompletedNCT05046795Phase 3Results posted
• Efficacy and Safety of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Chinese Participants With Inadequately Controlled AsthmaCompletedNCT04937387Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Fluticasone Furoate (FF)/Umeclidinium(UMEC)/Vilanterol (VI) in Participants With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT04923347Phase 4Results posted
• Functional Respiratory Imaging Study (DARWiIN)CompletedNCT04876677Phase 3Results posted
• An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5)CompletedNCT04820309Phase 3Results posted
• A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3)CompletedNCT04738123Phase 3Results posted
• An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4)CompletedNCT04659174Phase 3Results posted
• A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2)CompletedNCT04659161Phase 3Results posted
• Feasibility, Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPDCompletedNCT04655170Phase 4Results posted
• Evaluation of Triple Therapy Using Magnetic Resonance Imaging in AsthmaActive, not recruitingNCT04651777Phase 3Results posted
• Defining and Treating Depression-related AsthmaCompletedNCT04617015Early Phase 1Results posted
• Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)CompletedNCT04609904Phase 3Results posted
• Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)CompletedNCT04609878Phase 3Results posted
• Comparison of Time to Extubation Using Sugammadex or NeostigmineCompletedNCT04606901Phase 4Results posted
• Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate CancerCompletedNCT04600336Phase 2Results posted
• Study to Gather Information About the Actual Use of an Adhesive Patch Placed on the Skin to Deliver Oxytrol Through the Skin Into the Bloodstream.CompletedNCT04534491Phase 3Results posted
• Revefenacin in Acute Respiratory Insufficiency in COPDCompletedNCT04315558Phase 2Results posted
• Sublingual vs IV Atropine Bioavailability StudyCompletedNCT04290039Phase 1Results posted
• Investigation of Brain Mechanisms Involved in Urgency Urinary IncontinenceCompletedNCT04227184Phase 4Results posted
• A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to InhaleCompletedNCT04223843Phase 4Results posted
• Scopolamine in Bipolar DepressionCompletedNCT04211961Phase 2Results posted
• Medications for Obstructive Sleep Apnea In Children With Down SyndromeCompletedNCT04115878Phase 2Results posted
• Fall Prevention in Older Adults With OABCompletedNCT03946124Phase 4Results posted
• Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting SurgeryCompletedNCT03939923Phase 4Results posted
• A Novel Pharmacological Therapy for Obstructive Sleep ApneaCompletedNCT03919955Phase 2Results posted
• The Safety and Efficacy of SYD-101 in Children With MyopiaCompletedNCT03918915Phase 3Results posted
• Low-dose Atropine for the Prevention of Myopia Progression in Danish ChildrenCompletedNCT03911271Phase 2Results posted
• A Study to Evaluate the Effects of BGF and GFF on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPDCompletedNCT03836677Phase 3Results posted
• Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil DilationCompletedNCT03751631Phase 3Results posted
• Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil DilationCompletedNCT03751098Phase 3Results posted
• Use of Hyoscyamine Versus Tamsulosin for Management of Ureteral Stent IrritationTerminatedNCT03750656Phase 4Results posted
• Intraoperative Video Laryngoscopy as Adjunct for Nerve MonitoringCompletedNCT03742141Not applicableResults posted
• A Study to Assess Safety and Efficacy of KarXT in Adult Patients With SchizophreniaCompletedNCT03697252Phase 2Results posted
• Side Effects of Atropine (SEA) StudyCompletedNCT03593044Phase 1/2Results posted
• Efficacy and Safety Evaluating Study to Compare Uritos® (Imidafenacin) and Urotol® (Tolterodine) for Treatment of Overactive Bladder.CompletedNCT03575702Phase 3Results posted
• A 42-day Parallel Group Safety Study of Revefenacin and Formoterol, Administered in Sequence and as a Combination, in Participants With COPDCompletedNCT03573817Phase 3Results posted
• A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC /VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03478696Phase 4Results posted
• A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03478683Phase 4Results posted
• A Comparative Study Between Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy Versus Tiotropium Monotherapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03474081Phase 4Results posted
• INTREPID: Investigation of TRELEGY Effectiveness: Usual Practice DesignCompletedNCT03467425Phase 4Results posted
• Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve GastrectomyCompletedNCT03435003Phase 4Results posted
• The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major DepressionCompletedNCT03386448Phase 4Results posted
• Topical Application of Low-concentration (0.01%) Atropine on the Human Eye With Fast and Slow Myopia Progression RateCompletedNCT03374306Not applicableResults posted
• Patient-controlled Sedation With Propofol Versus Combined Sedation During BronchoscopyCompletedNCT03357393Not applicableResults posted
• Low-Dose Atropine for Treatment of MyopiaCompletedNCT03334253Phase 3Results posted
• A Phase I, Open-Label, Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide in Healthy Chinese ParticipantsCompletedNCT03276052Phase 1Results posted
• Study to Assess the Safety and Efficacy of PT010, PT003, and PT009 in Japanese Subjects With COPD Compared With Symbicort® Turbohaler®CompletedNCT03262012Phase 3Results posted
• The ENERGITO® 2 Study Compares 2 Inhaled Medicines for Chronic Obstructive Pulmonary Disease (COPD). One Medicine is a Combination of Tiotropium and Olodaterol (Stiolto®) Taken Using the Respimat® Inhaler and the Other Medicine is a Combination of Fluticasone and Salmeterol Taken Using the DiskusCompletedNCT03240575Phase 4Results posted
• Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)TerminatedNCT03219866Phase 4Results posted
• Effect of Heat on Oxybutynin Release and Absorption From Oxybutynin ProductsCompletedNCT03205605Early Phase 1Results posted
• Efficacy of Intermittent Tiotropium in Early Childhood WheezingTerminatedNCT03199976Phase 4Results posted
• Efficacy and Safety of Glycopyrronium/Formoterol Fumarate Fixed-dose Combination Relative to Umeclidinium/Vilanterol Fixed-dose Combination Over 24 Weeks in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary DiseaseCompletedNCT03162055Phase 3Results posted
• Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson DiseaseCompletedNCT03149809Phase 3Results posted
• Bronchodilator Effects and Safety of Glycopyrronium Bromide (25 ug and 50 ug o.d.) in AsthmaCompletedNCT03137784Phase 2/3Results posted
• Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03118765Phase 2Results posted
• Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle RelaxantCompletedNCT03116997Phase 3Results posted
• Use of Sugammadex for Reversal of Paralysis in MicrolaryngoscopyCompletedNCT03111121Phase 4Results posted
• Revefenacin Peak Inspiratory Flow Rate (PIFR) Study in COPDCompletedNCT03095456Phase 3Results posted
• A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary DiseaseCompletedNCT03084796Phase 2Results posted
• Effects of TD-4208 on FEV1 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT03064113Phase 2Results posted
• Cardiovascular Function in COPD PatientsCompletedNCT03055988Phase 4Results posted
• Scopolamine Patch Pharmacokinetics in Healthy AdultsCompletedNCT03029650Phase 4Results posted
• The Effects of RPL554 in Addition to Tiotropium in COPD PatientsCompletedNCT03028142Phase 2Results posted
• Study to Assess Efficacy and Safety of Aclidinium Bromide and Aclidinium Bromide/Formoterol Fumarate in Stabile COPD PatientsCompletedNCT03022097Phase 3Results posted
• Phase IIb Study of Umeclidinium (UMEC) Bromide Versus Placebo in Subjects With AsthmaCompletedNCT03012061Phase 2Results posted
• Bioavailability of Tiotropium + Olodaterol Fixed-dose Combination (5 μg/ 5 μg) in Chinese COPD PatientsCompletedNCT02969317Phase 1Results posted
• Oxybutynin Chloride in Managing Hot FlashesCompletedNCT02961790Phase 3Results posted
• Scopolamine Patch and Acupressure Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean SectionCompletedNCT02960113Phase 4Results posted
• A Study to Assess the Effects of PT001 and PT005 MDI on Specific Image Based Parameters in Subjects With Moderate to Severe COPDCompletedNCT02937584Phase 3Results posted
• Atropine in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)CompletedNCT02927223Not applicableResults posted
• TAK-071 Scopolamine-Induced Cognitive Impairment StudyTerminatedNCT02918266Phase 1Results posted
• Optimal Method for Mydriasis in Cataract SurgeryTerminatedNCT02909140Not applicableResults posted
• Minimizing Nausea and Vomiting During Spinals for CSTerminatedNCT02872935Phase 4Results posted
• RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials CooperativeCompletedNCT02867761Phase 3Results posted
• AMPLIFY - D6571C00001 Duaklir USA Phase III StudyCompletedNCT02796677Phase 3Results posted
• Comparative Study of Fluticasone Furoate(FF)/Umeclidinium Bromide (UMEC)/ Vilanterol (VI) Closed Therapy Versus FF/VI Plus UMEC Open Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT02729051Phase 3Results posted
• Study to Evaluate the Treatment Effect of PT003 on Cardiovascular Hemodynamics in Subjects With Moderate to Severe COPDTerminatedNCT02685293Phase 3Results posted
• A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis SubjectsCompletedNCT02673619Phase 2Results posted
• Orphenadrine and Methocarbamol for LBPCompletedNCT02665286Phase 4Results posted
• A Pilot Study Exploring the Efficacy and Safety of Topical Oxybutynin 3% Gel for Primary Focal Hyperhidrosis in Adolescents and Young AdultsCompletedNCT02633371Not applicableResults posted
• Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted

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