Lyso-Thermosensitive Liposome Doxorubicin clinical trials
How each study uses Lyso-Thermosensitive Liposome Doxorubicin is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
11 studies that test it; most in 2014 (2)
| Year | Studies |
|---|---|
| 2006 | 1 |
| 2007 | 1 |
| 2008 | 1 |
| 2011 | 1 |
| 2012 | 1 |
| 2014 | 2 |
| 2017 | 1 |
| 2021 | 2 |
| 2022 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 6 · Other 5
Imunon (6) · University of Oxford (2) · Duke University (1) · UMC Utrecht (1) · Children's National Research Institute (1)
Often tested with
Tested in the same studies.
Liposomal doxorubicin (1) · Doxorubicin (1) · Cyclophosphamide (1) · High-Intensity Focused Ultrasound Ablation (1)
Studies
Open first, then newest update. How each study uses Lyso-Thermosensitive Liposome Doxorubicin is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 11
- A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid TumorsWithdrawnPhase 2Children's National Research InstituteNCT04791228Written as Lyso-thermosensitive Liposomal Doxorubicin
- Study of ThermoDox With Standardized Radiofrequency Ablation (RFA) for Treatment of Hepatocellular Carcinoma (HCC)CompletedPhase 3ImunonNCT02112656Written as ThermoDox
- Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC)CompletedPhase 3ImunonNCT00617981Written as ThermoDox
- PanDox: Targeted Doxorubicin in Pancreatic TumoursWithdrawnPhase 1University of OxfordNCT04852367Written as ThermoDox
- Phase 2 Study of Thermodox as Adjuvant Therapy With Thermal Ablation (RFA) in Treatment of Metastatic Colorectal Cancer(mCRC)TerminatedPhase 2ImunonNCT01464593Written as ThermoDox
- Heat-Activated Target Therapy of Local-Regional Relapse in Breast Cancer PatientsWithdrawnPhase 2ImunonNCT02850419Written as ThermoDox (Thermally Sensitive Liposomal Doxorubicin)
- Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast CancerStatus unknownPhase 1UMC UtrechtNCT03749850Written as LTLD
- Targeted Chemotherapy Using Focused Ultrasound for Liver TumoursCompletedPhase 1University of OxfordNCT02181075Written as ThermoDox® (LTLD)
- A Study of ThermoDox™ in Combination With Radiofrequency Ablation (RFA) in Primary and Metastatic Tumors of the LiverCompletedPhase 1ImunonNCT00441376Written as ThermoDox
- MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone MetastasesWithdrawnPhase 2ImunonNCT01640847Written as High Intensity Focused Ultrasound (HIFU) in combination with ThermoDox
- Temperature-Sensitive Liposomal Doxorubicin and Hyperthermia in Treating Women With Locally Recurrent Breast CancerTerminatedPhase 1Duke UniversityNCT00346229Written as lyso-thermosensitive liposomal doxorubicin(Thermodox)