Janus Kinase Inhibitors: all 1,428 studies that test it

Page 4 of 15. Open to participants first (328), then studies with results posted, then the rest; newest registration first within each.

• Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative ColitisNot yet recruitingNCT05112263Not applicable
• Comparison of Tofacitinib and Methotrexate in Takayasu's ArteritisRecruitingNCT05102448Phase 4
• Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung CancerRecruitingNCT05098210Phase 1
• A Study of Elritercept Alone or Together With Ruxolitinib in Adults With MyelofibrosisRecruitingNCT05037760Phase 2
• A Study of Ruxolitinib and Duvelisib in People With LymphomaRecruitingNCT05010005Phase 1
• ConsideRAte Study - Splenic Stimulation for RARecruitingNCT05003310Not applicable
• Better After CHoosing. Randomly Allocated or Patient Preference Based Treatment With Filgotinib or TNFi in RA (BACH)RecruitingNCT04985435Phase 4
• Baricitinib in Patients With Relapsing or naïve DermatomyositisRecruitingNCT04972760Phase 3
• Study of Salvage Therapy to Treat Patients With Granulomatosis With PolyangiitisRecruitingNCT04871191Phase 3
• Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative NeoplasmsRecruitingNCT04858256Phase 2
• Safety and Efficacy of Itacitinib in Adults With Systemic SclerosisRecruitingNCT04789850Phase 2
• A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque PsoriasisRecruitingNCT04772079Phase 3
• Ruxolitinib in Thrombocythemia and Polycythemia VeraRecruitingNCT04644211Phase 2
• Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic ArthritisRecruitingNCT04610476Phase 3
• Randomised Evaluation of COVID-19 TherapyRecruitingNCT04381936Phase 3
• Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary MyelofibrosisRecruitingNCT04370301Phase 2
• Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic AdenocarcinomaRecruitingNCT04303403Phase 1
• Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative NeoplasmsRecruitingNCT04282187Phase 2
• MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia VeraRecruitingNCT04116502Phase 3
• Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO)RecruitingNCT04061421Phase 1/2
• Advanced Therapeutics in Rheumatoid Arthritis (RA)RecruitingNCT03976245Phase 4
• A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic ArthritisRecruitingNCT03773965Phase 3
• Examination of Efficacy and Safety of Baricitinib in RA PatientsRecruitingNCT03755466Phase 2
• Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin LymphomaRecruitingNCT03681561Phase 1/2
• Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic LeukemiaRecruitingNCT03571321Phase 1
• Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingNCT03414502Phase 3
• Study of Ruxolitinib in Relapsed or Refractory T or NK Cell LymphomaRecruitingNCT02974647Phase 2
• Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
• A Study Evaluating Deucravacitinib Concentrations in the Breast Milk and Plasma of Healthy Lactating Female ParticipantsCompletedNCT06476834Phase 4Results posted
• Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TENCompletedNCT06474078Not applicableResults posted
• Deucravacitinib (BMS-986165) for Pityriasis Rubra PilarisCompletedNCT06444399Phase 2Results posted
• A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic DermatitisCompletedNCT06238817Phase 3Results posted
• Effectiveness and Safety of Tofacitinib in Patients With Recalcitrant Frontal Fibrosing Alopecia : A Pilot StudyCompletedNCT06202560Not applicableResults posted
• A Study to Learn About Three Forms of The Study Medicine (Ritlecitinib) in Healthy AdultsCompletedNCT06172348Phase 1Results posted
• A Study of Deucravacitinib to Treat LPP and FFACompletedNCT06091956Phase 2Results posted
• A Study to Evaluate Effectiveness and Safety of Deucravacitinib in Participants With Non-Pustular Palmoplantar and Genital PsoriasisTerminatedNCT06042920Phase 4Results posted
• JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow FailureActive, not recruitingNCT05998408Phase 1/2Results posted
• JAK/STAT Inhibition in CNS Kohlmeier-Degos DiseaseCompletedNCT05998395Phase 1/2Results posted
• Evaluating the Safety and Efficacy of Deucravacitinib Compared to Placebo Hidradenitis Suppurativa (HS).TerminatedNCT05997277Phase 2Results posted
• Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous UrticariaCompletedNCT05936567Phase 2Results posted
• Topical Ruxolitinib Evaluation in Chronic Hand EczemaCompletedNCT05906628Phase 2Results posted
• A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult ParticipantsCompletedNCT05852340Phase 1Results posted
• Ruxolitinib in Seborrheic DermatitisCompletedNCT05787860Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)CompletedNCT05764161Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)CompletedNCT05755438Phase 3Results posted
• A Study to Assess the Safety and Efficacy of Ruxolitinib Cream in Participants With Genital VitiligoCompletedNCT05750823Phase 2Results posted
• A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe PsoriasisCompletedNCT05730725Phase 2Results posted
• Deucravacitinib for the Treatment of Palmoplantar PustulosisTerminatedNCT05710185Phase 4Results posted
• A Study to Evaluate the Effect of Deucravacitinib on Quality of Life in Participants With Plaque Psoriasis in a Community SettingCompletedNCT05701995Phase 4Results posted
• The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.TerminatedNCT05696392Phase 4Results posted
• Janus Kinase Inhibition in Granuloma AnnulareCompletedNCT05650736Phase 2Results posted
• A Study to Learn About the Study Medicine (Called Ritlecitinib) For the Potential Treatment of Severe Alopecia Areata (AA) In Children 6 To Less Than 12 Years of AgeCompletedNCT05650333Phase 1Results posted
• Study to Evaluate of the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis SuppurativaCompletedNCT05635838Phase 2Results posted
• A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic DermatitisCompletedNCT05601882Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque PsoriasisCompletedNCT05600036Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Lichen SclerosusCompletedNCT05593445Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen PlanusCompletedNCT05593432Phase 2Results posted
• Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies.TerminatedNCT05579769Phase 2Results posted
• A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia AreataTerminatedNCT05556265Phase 2Results posted
• Ritlecitinib for Cicatricial AlopeciaCompletedNCT05549934Phase 2Results posted
• A Study to Assess Treat-to-Target and Dosing Flexibility of Oral Upadacitinib Tablets in Adult Participants With Moderate to Severe Atopic DermatitisCompletedNCT05507580Phase 4Results posted
• A Study Evaluating the Effect of Filgotinib Dose De-escalation in Participants With Ulcerative Colitis (UC) in RemissionTerminatedNCT05479058Phase 3Results posted
• Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp PsoriasisCompletedNCT05478499Phase 4Results posted
• Study of Ruxolitinib Cream in Adolescents With Atopic DermatitisCompletedNCT05456529Phase 3Results posted
• A Study to Learn About Abrocitinib Tablets in People With Atopic Dermatitis in IndiaCompletedNCT05375929Phase 3Results posted
• Efficacy and Safety of Delgocitinib Cream in Adolescents 12-17 Years of Age With Moderate to Severe Chronic Hand EczemaCompletedNCT05355818Phase 3Results posted
• A Trial to Assess the Effect of Delgocitinib Cream 20 mg/g on the Molecular Signature, Safety, and Efficacy in Adults With Frontal Fibrosing AlopeciaCompletedNCT05332366Phase 2Results posted
• Topical Ruxolitinib in Chronic Hand DermatitisCompletedNCT05293717Phase 1/2Results posted
• Baricitinib for the Treatment of Ocular Mucous Membrane PemphigoidTerminatedNCT05263505Phase 2Results posted
• A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand EczemaCompletedNCT05259722Phase 3Results posted
• Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket TrialCompletedNCT05189106Phase 1/2Results posted
• Baricitinib (LY3009104) in the Treatment of Cutaneous Lichen PlanusCompletedNCT05188521Phase 2Results posted
• Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)CompletedNCT05177211Phase 2Results posted
• A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic ArthritisCompletedNCT05153148Phase 2Results posted
• A Target Occupancy Study With Ritlecitinib.CompletedNCT05128058Phase 1Results posted
• Ruxolitinib Cream in Participants With Facial and/or Neck Atopic Dermatitis InvolvementCompletedNCT05127421Phase 2Results posted
• Study to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of TolbutamideCompletedNCT05097716Phase 1Results posted
• Dual JAK1/TYK2 Inhibitor for Cicatricial AlopeciaCompletedNCT05076006Phase 2Results posted
• A Study of Baricitinib (LY3009104) in Children With COVID-19TerminatedNCT05074420Phase 3Results posted
• A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy ParticipantsCompletedNCT05067439Phase 1Results posted
• A Study to Evaluate the Efficacy and Safety of INCB054707 in Participants With Prurigo NodularisCompletedNCT05061693Phase 2Results posted
• Evaluation of Tofacitinib in Prevention of Photosensitivity in LupusCompletedNCT05048238Phase 1Results posted
• European Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia AreataCompletedNCT05041803Phase 3Results posted
• A Single Dose Study To Test Two Pediatric Forms Of Ritlecitinib Compared With Adult Ritlecitinib In Healthy AdultsCompletedNCT05040295Phase 1Results posted
• Efficacy of Abrocitinib for Reducing Pruritus in Adults With Prurigo Nodularis and Chronic Pruritus of Unknown OriginCompletedNCT05038982Phase 2Results posted
• Study of NDI-034858 in Participants With Moderate to Severe Plaque PsoriasisCompletedNCT04999839Phase 2Results posted
• Open-label Multi-site Extension Trial in Subjects Who Completed the DELTA 1 or DELTA 2 TrialsCompletedNCT04949841Phase 3Results posted
• Study to Evaluate Adverse Events and Change in Disease Activity With Oral Tablets of Upadacitinib in Adult Participants With Non-Segmental VitiligoCompletedNCT04927975Phase 2Results posted
• A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3)CompletedNCT04921969Phase 3Results posted
• Study of Ruxolitinib Cream for the Treatment of Discoid Lupus ErythematosusCompletedNCT04908280Phase 2Results posted
• A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic DrugsActive, not recruitingNCT04908202Phase 3Results posted
• A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor TreatmentActive, not recruitingNCT04908189Phase 3Results posted
• A Study Evaluating Relative Bioavailability of an Oral Suspension of Abrocitinib and Effect of an Acid Reducing Agent on the Bioavailability of Abrocitinib and Assessing the Taste of Abrocitinib Oral Formulations.CompletedNCT04903093Phase 1Results posted
• A Study to Evaluate the Mechanism of Action of Ruxolitinib Cream in Subjects With Vitiligo (TRuE-V MOA)CompletedNCT04896385Phase 2Results posted
• Phase 2 Study: An Open-Label, Randomized, Phase 2 Dose-Finding Study of Pacritinib in Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post- Essential Thrombocythemia Myelofibrosis Previously Treated With RuxolitinibCompletedNCT04884191Phase 2Results posted
• A Study to Evaluate the Long-term Safety and Efficacy of Deucravacitinib in Participants With Crohn's Disease or Ulcerative ColitisCompletedNCT04877990Phase 2Results posted
• Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand Eczema (DELTA 2)CompletedNCT04872101Phase 3Results posted
• Efficacy and Safety of Delgocitinib Cream in Adults With Moderate to Severe Chronic Hand EczemaCompletedNCT04871711Phase 3Results posted
• A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)Active, not recruitingNCT04857034Phase 2Results posted
• Study to Assess Efficacy and Safety of NS-018 Compared to BAT in Patients With MyelofibrosisTerminatedNCT04854096Phase 2Results posted

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