Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,715 studies that test it

Page 8 of 18. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.

• Preventing Cardiac Complication of COVID-19 Disease With Early Acute Coronary Syndrome Therapy: A Randomised Controlled Trial.TerminatedNCT04333407Not applicable
• The Role of Rosuvastatin on Vascular Involvement in Behçet's DiseaseCompletedNCT04328064Not applicable
• Bioequivalence Study Between "Dong-A Atorvastatin Tab" and "Lipitor Tab"Status unknownNCT04325009Phase 1
• Effect of Rosuvastatin on the Clinical Features of PreeclampsiaStatus unknownNCT04303806Phase 2
• Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell AnemiaCompletedNCT04301336Phase 2/3
• Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major DepressionCompletedNCT04301271Phase 2
• Lovastatin for Treatment of Brain Arteriovenous MalformationsStatus unknownNCT04297033Phase 2
• Prevention of Recurrence and Metastasis in Genetically High-Risk MelanomasWithdrawnNCT04285749Early Phase 1
• Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney DiseaseCompletedNCT04284657Phase 2
• A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677CompletedNCT04268394Phase 1
• Drug-drug-interaction Study of Ramipril, Amlodipine and AtorvastatinCompletedNCT04262765Phase 1
• A Clinical Trial to Compare the Pharmacokinetics and Tolerability of CKD-348CompletedNCT04258865Phase 1
• A Drug-Drug Interaction Study To Estimate The Effect Of Tafamidis On Rosuvastatin PharmacokineticsCompletedNCT04253353Phase 1
• Study to Learn the Effect of Drug BAY1817080 on the Way the Body Absorbs, Distributes and Excretes Another Drug Rosuvastatin in Healthy Adult ParticipantsCompletedNCT04252300Phase 1
• Treatment of Chronic Mountain SicknessCompletedNCT04251364Not applicable
• Drug-drug-interaction Study of Candesartan, Amlodipine and AtorvastatinCompletedNCT04245046Phase 1
• Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and MetforminCompletedNCT04231435Phase 1
• Effect of Tegoprazan or RAPA114 on Pharmacokinetic of Atorvastatin in Healthy Adult VolunteersCompletedNCT04221321Phase 1
• How Atorvastatin Affects the Gut Flora and Metabolomics?Status unknownNCT04215237Not applicable
• A 2-part Study to Investigate the Effect of Macitentan in Healthy Male ParticipantsCompletedNCT04211272Phase 1
• Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR TrialWithdrawnNCT04190433Phase 2
• Simvastatin in UveitisCompletedNCT04183387Phase 2
• PsA T2T Statin Trial on Carotid and Coronary AtherosclerosisWithdrawnNCT04176978Not applicable
• Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan/AmlodipineCompletedNCT04158076Phase 3
• Effect of Atorvastatin on 5-Fluorouracil Induced MucositisStatus unknownNCT04151355Not applicable
• Statin Treatment for UnruptureD Intracranial anEurysms StudyStatus unknownNCT04149483Phase 2
• One Versus Twice Daily Administration of Multiple Cardiovascular Agents in Patients With Ischemic Heart DiseaseStatus unknownNCT04148820Phase 4
• Effect of Lipid Lowering Agents on Diabetic Retinopathy and Cardiovascular Risk of Diabetic PatientsStatus unknownNCT04140201Phase 4
• Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC)Active, not recruitingNCT04133792Phase 3
• A Study to Assess the Drug-drug Interaction of BMS-963272 and RosuvastatinCompletedNCT04124003Phase 1
• Intensive Management of Blood Pressure and Cholesterol in Elderly Chinese With Hypertension and Atrial FibrillationActive, not recruitingNCT04111419Phase 4
• A Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate CancerCompletedNCT04094519Phase 1
• A Study of PF-06651600 Effect on Rosuvastatin Pharmacokinetics in Healthy ParticipantsCompletedNCT04092595Phase 1
• Statins for Prevention of Disease Progression and Hospitalization in Liver CirrhosisTerminatedNCT04072601Phase 4
• Comparison of High-dose Rosuvastatin Versus Low-dose Rosuvastatin Plus Ezetimibe on Carotid Plaque Inflammation in Patients With Acute Coronary SyndromeCompletedNCT04056169Phase 4
• Atorvastatin vs Colchicine in Decrease of Troponin I of High Sensitivity in Patients With Rheumatoid Arthritis.CompletedNCT04056039Phase 2
• Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and CarvedilolStatus unknownNCT04049786Phase 4
• Simvastatin in the Prevention of Recurrent PancreatitisTerminatedNCT04021498Phase 3
• Role of Statin in Venous Dysfunction in Patients With Venous Thromboembolism EventCompletedNCT03988101Phase 4
• Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth SocketStatus unknownNCT03981601Phase 2
• Survival Benefits of Statins in Breast Cancer PatientsStatus unknownNCT03971019Phase 3
• A Drug Interaction Study of KW-6356 With Midazolam, Caffeine, or RosuvastatinCompletedNCT03970798Phase 1
• 7-day Atorvastatin and Emotional ProcessingCompletedNCT03966859Not applicable
• Efficacy of Atorvastatin in Chronic Subdural HaematomaStatus unknownNCT03956368Phase 3
• Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral ContraceptivesCompletedNCT03954366Phase 1
• Phase IB Metformin, Digoxin, Simvastatin in Solid TumorsActive, not recruitingNCT03889795Phase 1
• The DEtermining Statin Intolerance FOr Rosuvastatin (DESIFOR) TrialStatus unknownNCT03889314Phase 4
• Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)CompletedNCT03885921Phase 3
• Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)CompletedNCT03884452Phase 3
• A Long-term Safety and Tolerability Study of Ezetimibe Plus Atorvastatin in Participants With Coronary Heart Disease, Multiple Risk Factors, or Hypercholesterolemia Not Controlled by Atorvastatin (P01418/MK-0653-032)CompletedNCT03882996Phase 3
• A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)CompletedNCT03882905Phase 3
• MUscle Side-Effects of Atorvastatin in Coronary PatientsCompletedNCT03874156Phase 4
• Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and TelmisartanCompletedNCT03872232Phase 3
• Comparison of Carvedilol and Atorvastatin for Preventing of Contrast-Induced Nephropathy.CompletedNCT03867994Phase 2
• An Efficacy and Safety Study of Ezetimibe (MK-0653, SCH 58235) in Addition to Atorvastatin Compared to Placebo in Participants With Primary Hypercholesterolemia (MK-0653-013)CompletedNCT03867110Phase 3
• Evaluate Efficacy and Safety of Ezetimibe/Rosuvastatin and Candesartan Cilexetil/Amlodipine Besylate Combination TabletsCompletedNCT03847506Phase 4
• Pharmaco-metabolomic Effects of Statins: METASTATINECompletedNCT03837925Phase 3
• From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1CompletedNCT03826940Not applicable
• Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive TroponinTerminatedNCT03820466Phase 3
• Study of PF-04965842 Effect on Rosuvastatin Pharmacokinetics in Healthy ParticipantsCompletedNCT03806101Phase 1
• Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and SimvastatinCompletedNCT03801733Phase 1
• Type 2 Diabetic Patients Maintained on Statin TherapyCompletedNCT03784703Phase 4
• Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF DevelopmentCompletedNCT03780673Phase 2/3
• Simvastatin Therapy in Patients With Dilated Cardiomyopathy.CompletedNCT03775070Phase 2
• The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and DiabetesStatus unknownNCT03771053Not applicable
• Teneligliptin and Atorvastatin DDI StudyCompletedNCT03769870Phase 1
• Comparative Evaluation Of 1.2% Atorvastatin and 1.2% Simvastatin Gel Local Drug Delivery And Redelivery In Chronic Periodontitis Subjects With Diabetes Mellitus: A Randomized Controlled Clinical Trial.CompletedNCT03745300Phase 2/3
• Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal HypertensionStatus unknownNCT03720067Phase 2/3
• A Clinical Study to Evaluate PK, PD, and PG of Rosuvastatin in the ElderlyCompletedNCT03715101Phase 1
• The PK Characteristics of the Co-administration of Rosuvastatin and Telmisartan/Amlodipine and JLP-1401 in Healthy Adult Volunteers VolunteersCompletedNCT03707899Phase 1
• Effect of Repeated Doses of DS-8500a on Pharmacokinetics of Rosuvastatin in Healthy VolunteersCompletedNCT03699774Phase 1
• Atorvastatin in Management of Newly Diagnosed ITPStatus unknownNCT03692754Phase 2/3
• "Efficacy Of 1.2% Rosuvastatin Gel In The Management Of Infrabony Defects"CompletedNCT03677297Phase 4
• Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective DrugsCompletedNCT03660293Not applicable
• Lesional Evaluation of High Risk Patients With Neoatherosclerosis Treated With Rosuvastatin and Eicosapentaenoic Acid Using Optical Coherence Tomography(OCT)[LINK IT TWO]Status unknownNCT03657758Phase 4
• Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated CirrhosisActive, not recruitingNCT03654053Phase 3
• NIRS to Diagnose SAMSStatus unknownNCT03653663Phase 4
• Indonesia Pravastatin to Prevent Preeclampsia StudyStatus unknownNCT03648970Phase 2
• Impact of Nurse-led Programme With Carotid Ultrasound on Addressing Cardiovascular Risk in Patients With ArthritisWithdrawnNCT03625089Not applicable
• Thyroid Hormone Replacement for Subclinical Hypothyroidism and Dyslipidemia in ASCVD (ThyroHeart-Lipid Study)Status unknownNCT03606824Not applicable
• Lipid-lowering Therapy IndividualizationCompletedNCT03604471Phase 4
• Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With SimvastatinStatus unknownNCT03599609Phase 1/2
• Efficacy and Safety of Combination of Rosuvastatin and Ezetimibe in Patients With Primary HypercholesterolemiaCompletedNCT03571087Phase 3
• Efficacy/Safety of Telmisartan/Amlodipine/Rosuvastatin in Hypertensive Patients With HyperlipidemiaCompletedNCT03566316Phase 3
• A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type MalignanciesActive, not recruitingNCT03560882Phase 1
• Lipid-lowering Therapies in Vietnamese Chronic Kidney Disease PopulationStatus unknownNCT03543774Phase 4
• China Protection Trial of Glucose Metabolism by Pitavastatin in Patients With Prediabetes and HypertensionStatus unknownNCT03532620Phase 4
• Compare Effects of Intensive Versus Conventional Lipid-lowering Therapy in Patients With Severe Atherosclerotic Renal Artery Stenosis Undergoing Stent PlacementCompletedNCT03521700Phase 2/3
• Synaptic Plasticity and Cognitive Function in RASopathiesTerminatedNCT03504501Phase 2
• Efficacy and Safety of HS-25 or in Combination With Atorvastatin in Chinese Adults With Primary HypercholesterolemiaStatus unknownNCT03464682Phase 3
• Drug-drug Interaction Following Oral Administration of Telmisartan/Amlodipine and Atorvastatin in Healthy Adult VolunteersCompletedNCT03461081Phase 1
• The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune ThrombocytopeniaStatus unknownNCT03460808Phase 1/2
• Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial.CompletedNCT03435744Phase 3
• Safety and Efficacy of Statins for Chinese Patients With DyslipidemiaStatus unknownNCT03418974Phase 4
• Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AISCompletedNCT03402204Phase 3
• Effects of Simvastatin on Uterine Leiomyoma SizeActive, not recruitingNCT03400826Phase 2
• Safety, Tolerability and PK of PXL770 in Healthy Male SubjectsCompletedNCT03395470Phase 1
• Preventive Arterial Wall Phenotype and Low-dose Fluvastatin/Valsartan CombinationCompletedNCT03393377Not applicable
• Multiple Sclerosis-Simvastatin Trial 2CompletedNCT03387670Phase 3
• A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult SubjectsCompletedNCT03363815Phase 1

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