Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,715 studies that test it
Page 6 of 18. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.
- A Study to Learn More About How Safe Nurandociguat is and How it Affects the Way the Body Processes Rosuvastatin and Dabigatran in Healthy AdultsWithdrawnNCT07515339Phase 1
- Atorvastatin Therapy in the Treatment of Dyslipidemia in Children With Steroid Sensitive Nephrotic SyndromeCompletedNCT07497776Phase 4
- Clinical Evaluation of Simcyp-Guided Simvastatin Dosing in Patients With Liver CirrhosisCompletedNCT07459972Phase 4
- A Clinical Study of the Effect of MK-2828 on Rosuvastatin or Furosemide in Healthy People (MK-2828-005)CompletedNCT07431866Phase 1
- A Clinical Trial of Enlicitide and Rosuvastatin in Healthy Adults (MK-0616-039)Active, not recruitingNCT07300280Phase 1
- Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and AtorvastatinCompletedNCT07268625Phase 1
- Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL CholesterolCompletedNCT07255820Phase 4
- Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult ParticipantsCompletedNCT07235748Phase 1
- A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and AtorvastatinCompletedNCT07235189Phase 1
- A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)Active, not recruitingNCT07216482Phase 3
- A Study in Healthy People to Test Whether BI 3000202 Affects How 2 Other Medicines (Rosuvastatin and Digoxin) Are Taken up in the BodyCompletedNCT07215260Phase 1
- Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and RosuvastatinCompletedNCT07201545Phase 1
- Effect of Locally Applied Simvastatin Gel on Dental Implant Stability and Marginal Bone LevelCompletedNCT07194447Not applicable
- Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and RosuvastatinCompletedNCT07182383Phase 1
- Atorvastatin Mitigates WMH-Related Cognitive Impairment by Reducing VCAM-1CompletedNCT07128212Not applicable
- Remedial Mechanism of Simvastatin and Ursodeoxycholic Acid in Liver Cirrhosis: Crosstalk of Bile Secretion, Gut Microbiome, and Host Immune ResponseTerminatedNCT07102979Not applicable
- A Clinical Trial of HRS-1301 on the Pharmacokinetics of Rosuvastatin Calcium Tablets in Healthy SubjectsCompletedNCT07097831Phase 1
- A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Rosuvastatin in Healthy ParticipantsCompletedNCT07088913Phase 1
- Treatment of Bile Acid Diarrhoea With AtorvastatinActive, not recruitingNCT07042165Phase 4
- A Study to Assess the Effects of BPN14770 on RosuvastatinCompletedNCT07011992Phase 1
- A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult ParticipantsActive, not recruitingNCT06982131Phase 1
- A Phase 1 Study of PROT-001.CompletedNCT06981299Phase 1
- A Drug-drug Interaction Study to Investigate the Pharmacokinetic Interactions Between CKD-508, Midazolam, and Rosuvastatin in Healthy Adult Male ParticipantsCompletedNCT06979973Phase 1
- A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy ParticipantsCompletedNCT06948747Phase 1
- A Study to Investigate How AZD4144 Affects the Pharmacokinetics of Rosuvastatin in Healthy ParticipantsCompletedNCT06925854Phase 1
- A Study to Evaluate the Drug-Drug Interaction of EDP-323 With Midazolam, Caffeine, and Rosuvastatin in Healthy ParticipantsCompletedNCT06917508Phase 1
- Impact of Rosuvastatin Doses on LDL Levels, CPK Levels and Aspartate Aminotransferase LevelsCompletedNCT06910098Not applicable
- The Effect of Atorvastatin 80 mg on Hs-CRP/Albumin Ratio in Reducing Thrombus Burden in PCI-STEMI PatientsCompletedNCT06871358Not applicable
- Combined Effects of Statins and Exercise on Training Sensitive Health MarkersCompletedNCT06841536Not applicable
- Polygenic Risk Driven Pragmatic Statin Trial for Heart Disease PreventionActive, not recruitingNCT06820086Phase 4
- A Research Study of the Effect of Etavopivat on Other Drugs in Healthy ParticipantsCompletedNCT06813924Phase 1
- The GABAergic Inhibitory System in Drug Resistant EpilepsyCompletedNCT06789497Not applicable
- Efficacy and Safety of Atorvastatin and Ezetimibe (10/10mg) Fixed Dose Combination Versus Atorvastatin (20mg) Monotherapy in Bangladeshi PopulationWithdrawnNCT06789432Phase 4
- Comparison of Moderate-Intensity Statin Plus Ezetimibe vs. High-Intensity Statin for Coronary Plaque StabilizationActive, not recruitingNCT06767345Phase 4
- A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.CompletedNCT06742853Phase 1
- Influence of HRS9531 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin in Healthy SubjectsCompletedNCT06723691Phase 1
- A Study to Evaluate the Drug-Drug Interaction Between Enlicitide Decanoate (MK-0616) and Atorvastatin in Healthy Adult Participants (MK-0616-024)CompletedNCT06699355Phase 1
- A Study of LY4065967 in Healthy Japanese ParticipantsCompletedNCT06594159Phase 1
- A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or ObeseCompletedNCT06567327Phase 1
- Ultra-early STatin in Patients With Aneurysmal subaRachnoid Hemorrhage (Ue-STAR)WithdrawnNCT06559072Phase 3
- A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy ParticipantsCompletedNCT06554821Phase 1
- Statins Effect on Incidence of Side Effects of Platinum Based ChemotherapyCompletedNCT06553157Phase 1/2
- A Drug-drug Interaction Study Evaluating the Perpetrator Potential of LY4100511 (DC-853) on Midazolam, Repaglinide, Digoxin, Rosuvastatin in Healthy ParticipantsCompletedNCT06503679Phase 1
- Study to Evaluate the Bioequivalence of "Crecheck Tablet 2.5 mg (Rosuvastatin Calcium)" and "Crestor Tablet 5 mg (Rosuvastatin Calcium)" in Healthy Adult SubjectsCompletedNCT06475872Phase 1
- An Exploratory Clinical Study of Statins for Improving Chemotherapy and Maintenance in Patients With Ovarian CancerStatus unknownNCT06468254Phase 2
- A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult ParticipantsCompletedNCT06416800Phase 1
- Effect of Pitavastatin on BoneCompletedNCT06359353Phase 4
- Detoxification From the Lipid TractCompletedNCT06357104Phase 4
- A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or DigoxinCompletedNCT06335134Phase 1
- A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy ParticipantsCompletedNCT06329895Phase 1
- ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy ParticipantsCompletedNCT06293742Phase 1
- A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightCompletedNCT06289504Phase 1
- Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese SubjectsCompletedNCT06247748Phase 1
- Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of SimvastatinCompletedNCT06207682Phase 1
- Atorvastatin for Preventing Disease Metastasis in Patients With Resected High-Risk Stage IIA, IIB, or IIIA MelanomaActive, not recruitingNCT06157099Phase 2
- Ameliorating Contrast Induced Nephropathy After Coronary AngiographyCompletedNCT06139952Phase 4
- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(6)CompletedNCT06112678Phase 1
- A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy ParticipantsCompletedNCT06111521Phase 1
- Clinical Effects of New Approach on Patients With Non-alcoholic SteatohepatitisCompletedNCT06105060Early Phase 1
- Statins in Patients With Spontaneous Intracerebral HemorrhageCompletedNCT06094244Not applicable
- A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and RosuvastatinCompletedNCT06081166Phase 1
- Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and CarbamazepineCompletedNCT06071442Phase 1
- Comparison Between Atorvastatin and Rosuvastatin in Reduction of Inflammatory Biomarkers in Patients With Acute Coronary SyndromeCompletedNCT06053983Phase 4
- Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and RifampinCompletedNCT06031454Phase 1
- Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone ChangesCompletedNCT06016218Phase 1/2
- Repurposed Drugs in Research for Cancer Clinical Trials- PitavastatinCompletedNCT05977738Early Phase 1
- Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125ACompletedNCT05970679Phase 3
- Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and ProbenecidCompletedNCT05954624Phase 1
- A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary HypercholesterolemiaCompletedNCT05930028Phase 3
- Comparison Between the Effects of High Doses Statin on Ventricular Remodeling in STEMI PatientsCompletedNCT05895123Phase 2
- Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and ColchicineActive, not recruitingNCT05850091Phase 4
- COVID-19 Vaccination Detoxification in LDL-CActive, not recruitingNCT05839236Phase 1
- A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese SubjectsCompletedNCT05815680Phase 1
- Effects of High Intensity Statin Therapy on Steroid Hormones and Vitamin D in Type 2 Diabetic MenCompletedNCT05806723Phase 4
- Clinical Study to Evaluate the Possible Efficacy of Dapagliflozin and Atorvastatin in Patients With Major Depressive DisordersCompletedNCT05792540Phase 2
- Role of Statin Therapy in Prevention of Anthracycline-Induced CardiotoxicityStatus unknownNCT05792293Phase 2/3
- LDL-c Level Variability and Trained ImmunityCompletedNCT05790499Not applicable
- A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy VolunteersCompletedNCT05789342Phase 1
- A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.CompletedNCT05787002Phase 1
- A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male SubjectsCompletedNCT05768360Phase 1
- A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(5)CompletedNCT05749861Phase 1
- A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment PatientsStatus unknownNCT05747768Phase 4
- A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the BloodCompletedNCT05738291Phase 1
- The Effect of Statin Treatment on Arterial Wall Inflammation as Assessed With 68Ga-DOTATATE PET-CTCompletedNCT05730634Not applicable
- Potential Drug Interaction Between ALXN2040 and RosuvastatinCompletedNCT05708573Phase 1
- Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.CompletedNCT05681273Phase 1
- Platform Adaptive Embedded Trial for Acute Respiratory Distress SyndromeStatus unknownNCT05658692Phase 4
- Bioequivalence Study of Two Formulations of Atorvastatin Film-coated Tablets 40 mg in Healthy Volunteers Under Fasting ConditionsCompletedNCT05642845Phase 1
- A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy ParticipantsCompletedNCT05615012Phase 1
- Effect of Very Early and Rapid Lowering Cholesterol With Evolocumab on Left Ventricular Remodeling in Patients With Anterior STEMI Undergoing Primary PCITerminatedNCT05613426Phase 4
- Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy SubjectsCompletedNCT05594615Phase 1
- Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging SubstudyActive, not recruitingNCT05586750Phase 4
- Clinical & Biochemical Effect of Atorvastatin in Nano Particles Gel in Periodontitis TreatmentCompletedNCT05583643Phase 1
- Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary MolarsCompletedNCT05582317Not applicable
- A Study of LY3526318 in Healthy Male Japanese ParticipantsWithdrawnNCT05580250Phase 1
- Atorvastatin Efficacy and Safety in Patients With Ulcerative ColitisCompletedNCT05567068Phase 2
- Statin Impact on Hepatic DecompensationCompletedNCT05563389Phase 2/3
- Atorvastatin in Patients With Ulcerative ColitisCompletedNCT05561062Phase 2
- Effects of Usage of Simvastatin in Mild to Moderate Traumatic Brain Injury (TBI) Patients. Could it Make a Difference?Status unknownNCT05551871Not applicable
- Evaluation of the Effect in Platelet Count of Atorvastatin and N-acetyl CysteineCompletedNCT05551624Early Phase 1