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Status unknownNCT03981601Updated Jun 11, 2019

Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth Socket

A Phase 2 interventional study of Lovastatin 40 MG and without drug with Bone graft in Bone Loss, sponsored by Islamic Azad University, Sanandaj. Status unknown at 1 site in Iran, Islamic Republic of. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-06-11.

Sponsored by Islamic Azad University, Sanandaj · Phase 2, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jun 2019), so the status shown — last known as Recruiting — may be out of date.

From the registry’s dates

  • Registered 11 months after the study started (first participant enrolled Feb 2018, registered Feb 2019).
Phase
Phase 2
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which have more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected.

Read the detailed description

twenty healthy patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which has more than 20 teeth, are over 18 years old and require socket preservation surgery to tooth extraction for the periodontal problem, caries or Fractures were selected. moreover, divided the socket randomly to two groups(A, B)including A: bone graft with lovastatin and B: bone graft alone, after 3 months with trephine will collect the samples. following the histomorphometric analysis.

02

Conditions studied

  • Bone Loss
03

In context

Lead sponsor

Islamic Azad University, Sanandaj is the lead sponsor of 26 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. at least 18 years old
  2. tooth fracture, root caries
  3. Patients are volunteered for placement of the implant

Exclusion criteria

Exclusion Criteria:

  1. systemic diseases
  2. Pregnancy and breastfeeding
  3. malignancy, radiation therapy,
  4. history of periodontal surgery during the six months ago.
  5. medicine(phosphonates, antibiotic,...)
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
20 participants (estimated)

Study arms

  • Active comparator
    lovastatin 40 mg with bone graft

    after tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket

    Drug: Lovastatin 40 MG

  • Active comparator
    without drug with bone graft

    after tooth extraction, put the bone graft wifin tooth socket

    Procedure: without drug with Bone graft

Interventions

  • DrugLovastatin 40 MG

    after tooth extraction, put teh lovastatin40 mg wif bone graft wifin tooth socket

    Also known as: Group A

  • Procedurewithout drug with Bone graft

    after tooth extraction, put teh bone graft wifin tooth socket

    Also known as: Group B

06

What researchers measure

Primary outcomes

  1. Socket preservation with Lovastatin as evaluated by the amount of bone formation volume

    Time frame: 3 month

07

Study locations

1 of 1 sites recruiting
  • Amirhossein Farahmand
    Tehran, 19, Iran, Islamic Republic of
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 11, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03981601
Lead sponsor
Islamic Azad University, Sanandaj
Responsible party
Amirhossein Farahmand (assistant prof, Islamic Azad University, Sanandaj) — Principal investigator
First posted
Jun 11, 2019
Start date
Feb 22, 2018
Primary completion
Mar 30, 2019
Completion
Jul 30, 2019 (estimated)
Last update
Jun 11, 2019

Study contacts

Amirhossein Farahmand, Assistant Prof
Contact
perio-implant@hotmail.com
+98 912 404 0359

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2019. You cannot join it, but the record below documents what was studied.

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