Hydroxymethylglutaryl-CoA Reductase Inhibitors: all 1,715 studies that test it

Page 7 of 18. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.

• Clinical Trial to Evaluate the Tolerability and the Pharmacokinetics of CKD-348CompletedNCT05549401Phase 1
• Simvastatin Nasal Rinses for the Treatment of COVID-19 Mediated DysomsiaWithdrawnNCT05542095Phase 1
• Efficacy and Safety of Pitavastatin and PCSK9 Inhibitors in Liver Transplant PatientsActive, not recruitingNCT05537948Phase 4
• Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8CompletedNCT05525013Not applicable
• Pravastatin as a Prophylactic to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass IndexCompletedNCT05524246Phase 1
• Allopurinol Versus Atorvastatin to Prevent Complications of Liver CirrhosisCompletedNCT05511766Phase 2/3
• Atorvastatin Therapy on Xanthoma in Alagille SyndromeCompletedNCT05488067Phase 4
• Atorvastatin Use and Portal Hypertension in Patients With Hepatitis B Virus-related Liver Cirrhosis: A Randomized Controlled TrialStatus unknownNCT05483894Phase 2
• A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Dabigatran and Rosuvastatin in Healthy Male SubjectsCompletedNCT05480475Phase 1
• Drug Interaction Study of ASC42 With AtorvastatinCompletedNCT05464628Phase 1
• Targeting Investigation and Treatment in Patients With Type 2 Myocardial InfarctionCompletedNCT05419583Not applicable
• A Study to Assess the Effect of AZD5462 on the Pharmacokinetics of Midazolam, Rosuvastatin and DigoxinCompletedNCT05395117Phase 1
• A Study to Assess the Drug Levels of CC-92480 After Coadministration With Rifampin and Itraconazole, and the Drug Levels of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy ParticipantsCompletedNCT05389722Phase 1
• A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy SubjectsCompletedNCT05384262Phase 1
• Salivary Bmp-2 Levels & Radiographic Measurement Of Bone Density at Extracted ToothCompletedNCT05369091Phase 4
• Fruquintinib DDI Study With P-gp and BCRP SubstratesCompletedNCT05368805Phase 1
• Atorvastatin as a Potential Adjunct to Misoprostol for Termination of PregnancyCompletedNCT05342974Early Phase 1
• Possible Protective Effect of Rosuvastatin in Chemotherapy-induced Cardiotoxicity in HER2 Positive Breast Cancer PatientsCompletedNCT05338723Phase 3
• A Study of LY3549492 in Participants With Type 2 Diabetes Mellitus (T2DM)CompletedNCT05327595Phase 1
• Statins in Patients With Type 2 Diabetes Mellitus and Previous History of Acute Coronary SyndromeCompletedNCT05306990Not applicable
• Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of SimvastatinCompletedNCT05306379Phase 1
• Statin InTensity to Prevent Coronary Artery Vasculopathy After Heart TransplantationWithdrawnNCT05251129Not applicable
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and DolutegravirCompletedNCT05236530Phase 1
• Effect of Statin Therapy on Mortality in Patients With Ventilator Associated PneumoniaCompletedNCT05230472Phase 4
• Bioequivalence Study of Rosuvastatin in Healthy Volunteers Under Fasting ConditionCompletedNCT05197517Phase 1
• A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(3)CompletedNCT05192356Phase 1
• To Study the Safety and Efficacy of Simvastatin in Patients With Hepatopulmonary Syndrome in Cirrhosis.Status unknownNCT05187715Not applicable
• Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)CompletedNCT05154123Phase 1
• Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic LeukemiaStatus unknownNCT05133310Phase 4
• Study of the Therapeutic Effect of Atorvastatin on the Clinical Outcomes in HER2 Negative Breast Cancer Patients"Status unknownNCT05103644Phase 2/3
• A Study of Lazertinib (JNJ-73841937) in Healthy ParticipantsCompletedNCT05076877Phase 1
• The Interaction of Herbs and StatinsCompletedNCT05072405Phase 4
• Comparison of Effects of Atorvastatin Versus Rosuvastatin on Cardiac Function in Heart Failure PatientsStatus unknownNCT05072054Phase 4
• Effect of Local Application of Platelet-rich Fibrin Scaffold Loaded With Simvastatin on Peri-implant Bone ChangesCompletedNCT05008068Phase 1
• A Drug-Drug Interaction Study of CTL0801 and CTL0802 Compared to Coadministration in Healthy Adult VolunteersCompletedNCT05002244Phase 1
• Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st ChemotherapyStatus unknownNCT04985201Phase 2
• Effect of Statin Preloading in STEMI in Improving PCI OutcomesStatus unknownNCT04974814Not applicable
• Simvastatin and Emotional Processing (OxSTEP)CompletedNCT04973800Not applicable
• Pemvidutide (ALT-801) DDI Study in Healthy VolunteersCompletedNCT04972396Phase 1
• Atorvastatin for Reduction of 28-day Mortality in COVID-19: RCTStatus unknownNCT04952350Phase 3
• Comparison of Atorvastatin and Pitavastatin on the Effect of HbA1c in AMI Patients With Abnormal Glucose MetabolismStatus unknownNCT04945122Phase 4
• Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting AneurysmsStatus unknownNCT04943783Not applicable
• Mechanisms and Interventions to Address Cardiovascular Risk of Gender-affirming Hormone Therapy in Trans MenWithdrawnNCT04922424Phase 1
• Statin TReatment for COVID-19 to Optimise NeuroloGical recovERyActive, not recruitingNCT04904536Phase 3
• Evaluation of the Effect of Long-term Lipid-lowering Therapy in STEMI Patients With Coronavirus Infection COVID-19Active, not recruitingNCT04900155Not applicable
• A Study to Learn How Much Rosuvastatin Gets Into the Blood When Taken With or Without Elinzanetant and to Learn About the Safety of Elinzanetant in Healthy ParticipantsCompletedNCT04889287Phase 1
• Drug Repurposing - Statins as Microbiota Modulating Agents in Ulcerative ColitisTerminatedNCT04883840Phase 2/3
• A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348(2)CompletedNCT04883658Phase 1
• Efficacy and Safety of the Fixed-dose Combination Atorvastatin/Fenofibrate vs Atorvastatin in Patients With T2D and DLP.Status unknownNCT04882293Phase 3
• A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy SubjectsCompletedNCT04859452Phase 1
• Impact of PCSK9 Inhibitors on Coronary Plaque Composition and Vulnerability Assessed by Optical Coherence TomographyCompletedNCT04851769Phase 4
• Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular DiseaseCompletedNCT04826354Phase 4
• Oral Statins and Protection From Hearing LossTerminatedNCT04826237Phase 4
• Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous DiseaseCompletedNCT04824911Phase 2
• The Use of Injectable Plasma Versus the Use of Simvastatin Gel in Surgical Management of Bony Defect in DentistryStatus unknownNCT04824898Phase 1
• Evaluation of the Effect of Rosuvastatin on Cisplatin-induced Nephrotoxicity and OtotoxicityStatus unknownNCT04817904Phase 2
• Simvastatin Around Immediate ImplantCompletedNCT04803500Phase 2
• HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)Status unknownNCT04801940Phase 3
• Atorvastatin Effect on Reduction of COPD ExacerbationsActive, not recruitingNCT04789057Phase 4
• The Prognosis of Lipid Reprogramming With Rosuvastatin, in Castrated Egyptian Prostate Cancer PatientsCompletedNCT04776889Phase 4
• Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative ColitisActive, not recruitingNCT04767984Phase 2
• Effect of Upstream Treatment With High Intensity Statin on the Outcomes of STMI Patients Treated With PPCIStatus unknownNCT04754789Phase 3
• Influence of Intensive Lipid-lowering on FFRCT (The FLOW-PROMOTE Study)Status unknownNCT04737408Phase 3
• Pravastatin Reduces Acute Phase Response of Zoledronic AcidStatus unknownNCT04719481Phase 4
• Could Early Atorvastatin Offer Anti Inflammatory Effects Upon Brain in Traumatic Head Injury?CompletedNCT04718155Not applicable
• Efficacy of Statin Addition to Neoadjuvant Chemotherapy Protocols for Breast CancerStatus unknownNCT04705909Phase 2/3
• Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st ChemotherapyStatus unknownNCT04698941Phase 2
• Anti-inflmmation Treatment in Mood Disorder and Deep Learning Prediction ModelStatus unknownNCT04685642Phase 4
• Statins for the Treatment of NASHActive, not recruitingNCT04679376Phase 2
• The Role of Statins in the Prevention of Contrast-induced Acute Kidney Injury in Patients With Cardiovascular DiseasesCompletedNCT04666389Not applicable
• A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of CKD-348CompletedNCT04660370Phase 1
• To Evaluate the Efficacy and Safety of Co-administrated Ezetimibe/Rosuvastatin and Telmisartan in Patients With Essential Hypertension and Primary HypercholesterolemiaStatus unknownNCT04659070Phase 3
• 7-day Simvastatin and Emotional ProcessingCompletedNCT04652089Phase 1/2
• Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMCStatus unknownNCT04631536Phase 3
• Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin HydrochlorideCompletedNCT04621669Phase 1
• Efficacy and Safety of Atorvastatin + Perindopril Fixed-Dose Combination S05167 in Adult Patients With Arterial Hypertension and DyslipidemiaTerminatedNCT04591808Phase 3
• A Clinical Trial to Evaluate the Pharmacokinetics and Tolerability of CKD-348CompletedNCT04587206Phase 1
• To Evaluate the Efficacy and Safety in Patients With Primary HypercholesterolemiaCompletedNCT04584736Phase 3
• Identification and Validation of Biomarkers for Breast Cancer Resistance Protein (BCRP)CompletedNCT04542382Phase 1
• Study to Assess the Effect of Branebrutinib on the Drug Levels of Rosuvastatin in Healthy ParticipantsCompletedNCT04515628Phase 1
• Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-CelActive, not recruitingNCT04514029Early Phase 1
• Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid LeukemiaCompletedNCT04512105Phase 1
• Rosuvastatin Evaluation as a Tuberculosis Treatment AdjunctStatus unknownNCT04504851Phase 2
• Drug-Drug Interaction Study Between EDP-938, Tacrolimus, Dabigatran, Rosuvastatin and Midazolam in Healthy SubjectsCompletedNCT04498741Phase 1
• Megestrol Acetate Plus Rosuvastatin in Young Women With Atypical Endometrial HyperplasiaCompletedNCT04491682Phase 2/3
• Megestrol Acetate Plus Rosuvastatin in Young Women With Early Endometrial CarcinomaCompletedNCT04491643Phase 2
• Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19CompletedNCT04486508Phase 3
• Atorvastatin Effects On Arterial Stiffness In HemodialysisCompletedNCT04472637Phase 2
• Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase Randomized IIb TrialCompletedNCT04466241Phase 2/3
• Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian CancerCompletedNCT04457089Early Phase 1
• A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.CompletedNCT04428086Phase 1
• Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast CancerCompletedNCT04418089Phase 2
• SystemIc iNflammation and Microvascular diSease PreventIon in psoRiatic diseasEWithdrawnNCT04417114Phase 4
• A Study Evaluating Drug Drug Interaction Between Milvexian and Atorvastatin in Healthy ParticipantsCompletedNCT04388501Phase 1
• Atorvastatin as Adjunctive Therapy in COVID-19Status unknownNCT04380402Phase 2
• Atorvastatin ± Aspirin in Lynch Syndrome SyndromeCompletedNCT04379999Early Phase 1
• Atorvastatin Effect on Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary InterventionCompletedNCT04375787Phase 4
• Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in ColombiaCompletedNCT04359095Phase 2/3
• Study of Ruxolitinib Plus Simvastatin in the Prevention and Treatment of Respiratory Failure of COVID-19.CompletedNCT04348695Phase 2
• Coronavirus Response - Active Support for Hospitalised Covid-19 PatientsWithdrawnNCT04343001Phase 3

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