Histone Deacetylase Inhibitors: all 1,242 studies that test it
Page 8 of 13. Open to participants first (144), then studies with results posted, then the rest; newest registration first within each.
- Chidamide Combined With PECM in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)Status unknownNCT03321890Phase 2
- Phase 2 Study of KHK2375 in Subjects With Advanced or Recurrent Breast CancerCompletedNCT03291886Phase 2
- Dietary Interventions and Butyrate Production in Behçet's PatientsCompletedNCT03274648Not applicable
- Chidamide With PET Regimen for Angioimmunoblastic T Cell Lymphoma (PET: Prednisone, Etoposide and Thalidomide)Status unknownNCT03273452Phase 2
- Chidamide With CHOP Regimen for de Novo PTCL Patients (CHOP: Cyclophosphamide, Etoposide, Vincristine and Prednisone; PTCL: Peripheral T Cell Lymphoma)Status unknownNCT03268889Not applicable
- Study of Chidamide as a Single-agent Treatment for Patients With Relapse or Refractory B-NHLStatus unknownNCT03245905Phase 2
- International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013)Status unknownNCT03243461Phase 3
- Assessment of Valproate on Ethanol WithdrawalTerminatedNCT03235531Phase 4
- Pembrolizumab (Immunotherapy Drug) in Combination With Guadecitabine and Mocetinostat (Epigenetic Drugs) for Patients With Advanced Lung Cancer.Active, not recruitingNCT03220477Phase 1
- Chidamide With R-CHOP Regimen for DLBCL PatientsStatus unknownNCT03201471Phase 2
- A Study to Evaluate the Pharmacokinetics of Entinostat in Adult Subjects With Normal and Impaired Renal FunctionCompletedNCT03192111Phase 1
- A Study to Examine the Effects of Entinostat on Midazolam in Healthy Adult SubjectsCompletedNCT03187015Phase 1
- Combination Therapy With Entinostat and Pembrolizumab in Relapsed and Refractory LymphomasActive, not recruitingNCT03179930Phase 2
- Durvalumab in Different Combinations With Pralatrexate, Romidepsin and Oral 5-Azacitidine for LymphomaStatus unknownNCT03161223Phase 1/2
- Chidamide Combined With Clad/Gem/Bu With AutoSCT in R/R Diffuse Large B Cell LymphomaStatus unknownNCT03151876Phase 2
- Evaluation of the Combination of Romidepsin and Carfilzomib in Relapsed/Refractory Peripheral T Cell Lymphoma PatientsCompletedNCT03141203Phase 1/2
- Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaActive, not recruitingNCT03117751Phase 2/3
- Sodium Valproate for GSDVCompletedNCT03112889Phase 2
- Clinical Trial to Determine Tolerable Dosis of Vorinostat in Patients With Mild Alzheimer DiseaseTerminatedNCT03056495Phase 1
- CKD-581 + Bortezomib + Dexamethasone in Patients With Previously Treated Multiple MyelomaStatus unknownNCT03051841Phase 1
- Early Administration of Romidepsin and 3BNC117 in Treatment-naïve HIV Patients Starting ARTCompletedNCT03041012Phase 2
- Efficacy and Safety of Chidamide in CBF LeukemiaActive, not recruitingNCT03031262Phase 1/2
- Phenobarbital Versus Valproate for Generalized Convulsive Status EpilepticusStatus unknownNCT03025906Phase 2
- Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma PatientsStatus unknownNCT03023358Phase 3
- Vorinostat in Patients With Class 2 High Risk Uveal MelanomaWithdrawnNCT03022565Early Phase 1
- Sodium Butyrate For Improving Cognitive Function In SchizophreniaWithdrawnNCT03010865Phase 2/3
- Safety,Tolerability and MTD KA2507 (HDAC6 Inhibitor) in Patients With Solid TumoursCompletedNCT03008018Phase 1
- Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral CavityWithdrawnNCT02993991Phase 1
- Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell LymphomaStatus unknownNCT02987244Phase 1/2
- Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed LymphomaWithdrawnNCT02961816Phase 2
- Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS)CompletedNCT02953301Phase 2
- Safety and Efficacy of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With ChemotherapyCompletedNCT02948075Phase 2
- Chidamide for Refractory/Relapsed Peripheral T Cell LymphomaStatus unknownNCT02944812Phase 2
- Selective HDAC6 Inhibitor ACY-241 in Combination With Ipilimumab and NivolumabCompletedNCT02935790Phase 1
- The Optimal Treatment for Treatment-resistant SchizophreniaStatus unknownNCT02926976Not applicable
- Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of EntinostatCompletedNCT02922946Phase 1
- A Study to Examine the Effect of Omeprazole, Famotidine, and an Acidic Beverage on the Pharmacokinetics of Entinostat in Healthy Adult SubjectsCompletedNCT02922933Phase 1
- Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or LymphomaCompletedNCT02909777Phase 1
- Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid TumorsCompletedNCT02909452Phase 1
- A Dose Ranging Pilot Study for Intracerebroventricular (ICV) Delivery of Valproate in Subjects With Temporal SeizuresCompletedNCT02899611Phase 1/2
- Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid TumorsCompletedNCT02897778Phase 1
- Valproic Acid for Idiopathic Nephrotic SyndromeStatus unknownNCT02896270Phase 2/3
- A Study of PDR001 in Combination With LCL161, Everolimus or PanobinostatCompletedNCT02890069Phase 1
- Chidamide for Advanced Cephalic and Cervical Adenocystic Carcinoma: Evaluation of Efficiency and SafetyStatus unknownNCT02883374Phase 2
- Differences Between Chidamide Taken Daily and Twice a Week in Therapeutic Effect，Pharmacokinetics, Pharmacodynamics and EB Virus ActivationStatus unknownNCT02878278Phase 2
- Study of Volasertib and Belinostat in Patients With Relapsed and Refractory Aggressive B-cell and T-cell LymphomasWithdrawnNCT02875002Phase 1
- A Study to Evaluate the Safety and Tolerability of Valproic Acid in Trauma Patients(Part 2)TerminatedNCT02872428Phase 1
- Chidamide With ICE Regimen for Relapsed/Refractory Peripheral T Cell LymphomaStatus unknownNCT02856997Phase 2
- Ricolinostat, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable or Metastatic CholangiocarcinomaWithdrawnNCT02856568Phase 1
- Valproic Acid With Methylprenisonlone for the Treatment of Acute GVHDStatus unknownNCT02848105Phase 2
- HDAC Inhibitor Vorinostat in Resistant BRAF V600 Mutated Advanced MelanomaCompletedNCT02836548Phase 1/2
- Entinostat in Chinese Postmenopausal Women Patients With Locally Recurrent or Metastatic Breast CancerCompletedNCT02833155Phase 1
- Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast CancerCompletedNCT02820961Phase 1
- Clinical Trial of Chidamide Combined With CHOP in Peripheral T-cell Lymphoma PatientsCompletedNCT02809573Phase 1
- Induction Therapy for Multiple Myeloma With Carfilzomib, Lenalidomide,Dexamethasone,PanobinostatWithdrawnNCT02802163Phase 1/2
- Influence of Valproic Acid on Extinction-based Therapy in Patients With Fear of Spiders.CompletedNCT02789813Phase 2
- Trial of Duvelisib in Combination With Either Romidepsin or Bortezomib in Relapsed/Refractory T-cell LymphomasCompletedNCT02783625Phase 1
- Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal CarcinomaStatus unknownNCT02761291Phase 1
- Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)Status unknownNCT02759601Phase 1/2
- Ph1 Volasertib Plus Romidepsin in R/R PTCL and CTCLWithdrawnNCT02757248Phase 1
- Panobinostat in Combination With Carfilzomib and Dexamethasone in Relapsed or Relapsed and Refractory Multiple MyelomaWithdrawnNCT02756663Phase 2
- Chidamide Plus R-CHOP in Elderly DLBCLStatus unknownNCT02753647Phase 2
- Chidamide Plus Chemotherapy in the Treatment of Peripheral T-cell LymphomaStatus unknownNCT02753543Phase 2
- Chidamide Combined With VDDT Regimen in the Relapse and Refractory Diffuse Large B Cell LymphomaStatus unknownNCT02733380Phase 2
- Safety, Tolerability and Pharmacokinetics of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With ChemotherapyCompletedNCT02728492Phase 1
- The Effects of Butyrate on Children With ObesityStatus unknownNCT02721953Phase 2/3
- Pilot Trial of the Effect of Vorinostat and AGS-004 on Persistent HIV-1 InfectionTerminatedNCT02707900Phase 1
- Belinostat Combined With Azacitidine/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Refractory or Relapsed LymphomaWithdrawnNCT02701673Phase 1/2
- Efficacy Study of Pembrolizumab With Entinostat to Treat Metastatic Melanoma of the EyeCompletedNCT02697630Phase 2
- Safety Study of HBI-8000 in Japanese Patients With Non Hodgkin's LymphomaCompletedNCT02697552Phase 1
- Establish the PK of Belinostat in Patients With Wild-type, Heterozygous, and Homozygous UGT1A1*28 GenotypesCompletedNCT02680795Phase 1
- To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.TerminatedNCT02679131Phase 1
- Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic SyndromeTerminatedNCT02676323Phase 1
- Sodium Butyrate For Improving Cognitive Function In SchizophreniaWithdrawnNCT02654405Phase 2/3
- Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent GlioblastomaTerminatedNCT02648633Phase 1
- Safety and Efficacy Study of SHAPE Gel in Alopecia AreataStatus unknownNCT02636244Phase 2
- Selective HDAC6 Inhibitor ACY 241 in Combination With Nivolumab in Patients With Unresectable Non Small Cell Lung CancerTerminatedNCT02635061Phase 1
- ACY-1215 + Nab-paclitaxel in Metastatic Breast CancerCompletedNCT02632071Phase 1
- Valproic Acid Plus Cisplatin and Cetuximab in Recurrent and/or Metastatic Squamous Cell Carcinoma of Head and NeckStatus unknownNCT02624128Phase 2
- A Study to Assess the Feasibility of Romidepsin Combined With Brentuximab Vedotin in Cutaneous T-cell LymphomaCompletedNCT02616965Phase 1
- Study to Evaluate the Safety and Effect of HIVconsv Vaccines in Combination With Histone Deacetylase Inhibitor Romidepsin on the Viral Rebound Kinetic After Treatment Interruption in Early Treated HIV-1 Infected IndividualsCompletedNCT02616874Phase 1
- Chemoprevention of Head and Neck Squamous Cell Carcinoma (HNSCC) With Valproic AcidCompletedNCT02608736Early Phase 1
- Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic MalignanciesCompletedNCT02576496Phase 1
- Dose Escalation Study of HBI-8000 in Combination With Paclitaxel and Trastuzumab in Women With Advanced or Metastatic HER2+ Breast CancerWithdrawnNCT02569489Phase 1
- ACY 241 in Combination With Paclitaxel in Patients With Advanced Solid TumorsCompletedNCT02551185Phase 1
- A Phase Ib Study of Belinostat With RDHAP Chemotherapy (Dexamethasone, Cytarabine, Cisplatinum) in Adults With Relapsed or Refractory Diffuse Large B-cell LymphomaWithdrawnNCT02532192Phase 1
- Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian CancerCompletedNCT02520115Phase 1
- Chidamide in Combination With Antiretroviral Therapy for Eradication of the Latent HIV-1 ReservoirCompletedNCT02513901Phase 1/2
- Romidepsin Maintenance After Allogeneic Stem Cell TransplantationCompletedNCT02512497Phase 1
- Trial of Chidamide in Combination With Exemestane in Patients With Advanced Breast CancerCompletedNCT02482753Phase 3
- Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV InfectionCompletedNCT02475915Phase 1/2
- Controlled Trial of Valproate Versus Risperidone in Young Children With Bipolar DisorderCompletedNCT02456454Phase 3
- Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast CancerActive, not recruitingNCT02453620Phase 1
- A Dose-Escalation Study of OBP-801 in Patients With Advanced Solid TumorsStatus unknownNCT02414516Phase 1
- Epigenetic Reprogramming in Relapse AMLTerminatedNCT02412475Phase 1
- Resminostat (YHI-1001) in Combination With Sorafenib in Asian Patients With Advanced Hepatocellular Carcinoma (HCC)CompletedNCT02400788Phase 1/2
- Study of ACY-241 Alone and in Combination With Pomalidomide and Dexamethasone in Multiple MyelomaTerminatedNCT02400242Phase 1
- CINC424A2X01B Rollover ProtocolActive, not recruitingNCT02386800Phase 4
- Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid LeukemiaTerminatedNCT02381548Phase 1
- Pharmacovigilance in Gerontopsychiatric PatientsTerminatedNCT02374567Phase 3