Histamine H1 Antagonists: all 350 studies that test it
Page 1 of 4. Open to participants first (49), then studies with results posted, then the rest; newest registration first within each.
- Metronomic Temozolomide With Dexbrompheniramine for Recurrent High-Grade Glioma/GlioblastomaNot yet recruitingNCT07859059Phase 1/2
- Ebastine for Adjuvant Treatment of Tumor Budding-Positive Liver Cancer After SurgeryNot yet recruitingNCT07734766Phase 4
- Neonatal White Matter Injury Trial (WRAP)RecruitingNCT07688746Phase 1
- Comparison of Propranolol, Flunarizine and Their Combination in Preventing Migraine in Adults in a Tertiary Care Hospital in BangladeshNot yet recruitingNCT07655700Phase 4
- A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingNCT07542756Phase 4
- Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester AbortionsRecruitingNCT07542730Phase 4
- Antihistamine for Prevention of HTR After Blood Primed CPBRecruitingNCT07536152Phase 4
- Mast Cell Treatment in Post-tick Bite Illness (PTBI)Not yet recruitingNCT07526558Phase 2
- Repurposing Mirtazapine in Rett SyndromeRecruitingNCT07430046Phase 2
- Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung CancerNot yet recruitingNCT07358689Phase 2
- Comparative Efficacy of Flunarizine and Propanolol in Pediatric MigraineRecruitingNCT07354126Not applicable
- Histamines and Central HemodynamicsRecruitingNCT07285031Not applicable
- Topical Ketotifen 0.25% for Secondary VestibulodyniaRecruitingNCT07257029Phase 2
- Effect of Ebastine in Patients With Diarrhea Predominant Irritable Bowel SyndromeRecruitingNCT07114055Phase 2/3
- Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration RepairsRecruitingNCT06910241Phase 3
- Phase III Clinical Study of Cetirizine Hydrochloride Injection in Treatment of Acute UrticariaRecruitingNCT06819774Phase 3
- Study of Tislelizumab and Platinum-based Chemotherapy Combination With H1 Receptor Antagonist（Diphenhydramine）in Advanced and Metastatic Non-Small Cell Lung CancerNot yet recruitingNCT06704620Phase 3
- Anticholinergics for Cervical Edema in LaborRecruitingNCT06702670Phase 2/3
- Study on the Effectiveness of Tranilast in the Treatment of Medium to Large Volume Benign Prostatic HyperplasiaRecruitingNCT06689514Early Phase 1
- Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a NeuromodulatorRecruitingNCT06684470Early Phase 1
- Study on Hibernation-like Therapy Based on Mechanical ThrombectomyRecruitingNCT06663631Phase 1
- Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial NeoplasmsNot yet recruitingNCT06643689Phase 2
- Clemastine for Improving White Matter and Boosting Antidepressant Response in Late-life DepressionRecruitingNCT06591091Phase 2
- Evaluating the Effect of Mirtazapine on Anxiety in Parkinson's Disease PatientsRecruitingNCT06530290Phase 2
- Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary CareNot yet recruitingNCT06499116Phase 4
- Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate CancerRecruitingNCT06480110Phase 1/2
- The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled TrialNot yet recruitingNCT06395064Not applicable
- Diphenhydramine in Catheter Related Bladder DiscomfortEnrolling by invitationNCT06345261Not applicable
- Mirtazapine for the Treatment of Methamphetamine Use in Opioid Use Disorder Patients Receiving Medication Assisted TreatmentRecruitingNCT06323837Phase 2
- Combining Clemastine and Aerobic Exercise to Treat Cognitive Dysfunction in Schizophrenia by Targeting Myelin PlasticityNot yet recruitingNCT06315972Phase 2
- Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of RosaceaEnrolling by invitationNCT06307288Phase 4
- Over-the-Counter Antihistamines & Heat StressRecruitingNCT06217367Phase 4
- Elucidating Mechanisms That Underlie the Symptomatology of Functional Dyspepsia Using Novel Techniques and Its Therapeutic Validation Using NeuromodulatorsRecruitingNCT06213948Phase 1
- Efficacy of Flunarizine Vs Amitriptyline in Prophylaxis of Migraine ProphylaxisNot yet recruitingNCT06162819Not applicable
- Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair TherapyNot yet recruitingNCT06065670Phase 1/2
- Efficacy of Hydroxyzine for Patients With Panic DisorderNot yet recruitingNCT05737511Phase 4
- Antazoline in Comparison to Propafenone in Pharmacological Cardioversion of Atrial Fibrillation.RecruitingNCT05720572Phase 4
- Tranilast as a Radiosensitizer in Reradiation of Nasopharyngeal CarcinomaRecruitingNCT05626829Phase 2
- The Possible Protective Role of Ketotifen Against Oxaliplatin Induced Peripheral NeuropathyRecruitingNCT05624138Phase 3
- A Study of Mianserin in Combination With SSRIs in Depression With Sleep ProblemsRecruitingNCT05599126Phase 4
- Trial of Diphenhydramine for Sleep in Children With AutismRecruitingNCT05501678Phase 2
- Serotonin Receptor Blockers in Ischemic Mitral RegurgitationRecruitingNCT05469165Phase 2
- Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair TherapyRecruitingNCT05359653Phase 1/2
- Comparing Olanzapine and Mirtazapine in the Improvement of Unintentional Weight Loss for Patients with Advanced Stage CancerEnrolling by invitationNCT05170919Phase 2
- Improving Sleep After TKA Using Mirtazapine and QuetiapineNot yet recruitingNCT04728581Not applicable
- Decoding Pain Sensitivity in Migraine With Multimodal Brainstem-based NeurosignatureRecruitingNCT04702971Phase 4
- Stem Cell Transplantation in Crohn's DiseaseRecruitingNCT04224558Phase 1/2
- Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)RecruitingNCT02521311Phase 2
- Ketotifen for Children With Functional Dyspepsia in Association With Duodenal EosinophiliaRecruitingNCT02484248Phase 3
- Pediatric Oncology Nutrition Intervention TrialCompletedNCT06175273Phase 2/3Results posted
- Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic ConjunctivitisCompletedNCT05591755Phase 3Results posted
- Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic ModelingTerminatedNCT05219604Phase 4Results posted
- Treatment of Pruritus With Intramuscular PromethazineCompletedNCT04805073Phase 4Results posted
- Role of Mirtazapine in Ameliorating Sleep Disordered BreathingCompletedNCT04799782Phase 2Results posted
- Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated DataCompletedNCT04606264Phase 3Results posted
- Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V DiphenhydramineCompletedNCT04189588Phase 2Results posted
- Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to OcrelizumabCompletedNCT04175834Phase 3Results posted
- Nutrition and Pharmacological Algorithm for Oncology Patients StudyTerminatedNCT04155008Phase 4Results posted
- Total Joint Arthroplasty and SleepCompletedNCT03968939Phase 4Results posted
- 5HT2CR Balance in Brain Connectivity in Cocaine DependenceCompletedNCT03921151Phase 1/2Results posted
- Cannabinoids vs. Placebo on Persistent Post-surgical Pain Following TKA: A Pilot RCTCompletedNCT03825965Phase 3Results posted
- Comparison of Therapeutic Effects of Greater Occipital Nerve Block, Topiramate, and Flunarizine on Episodic MigraineCompletedNCT03712917Not applicableResults posted
- TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency SettingCompletedNCT03639558Phase 4Results posted
- A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and VehicleCompletedNCT03489941Phase 3Results posted
- Clinical Evaluation of Etafilcon A With KetotifenCompletedNCT03388138Phase 2Results posted
- A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMTTerminatedNCT03368664Phase 3Results posted
- Safety and Efficacy of Isatuximab in Lymphoblastic LeukemiaTerminatedNCT02999633Phase 2Results posted
- Treg Therapy in Subclinical Inflammation in Kidney TransplantationCompletedNCT02711826Phase 1/2Results posted
- A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and ComorbidityCompletedNCT02655354Not applicableResults posted
- Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication TrialCompletedNCT02646449Phase 2Results posted
- Effectiveness of Triple Therapy With Palonosetron for PON ProphylaxisCompletedNCT02635828Phase 4Results posted
- Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted
- Evaluation of Diphenhydramine Hydrochloride Effects in Subjects With Occasional SleeplessnessCompletedNCT02578186Phase 4Results posted
- Effects of Cyproheptadine on Growth and Behavior in Pediatric Feeding DisordersTerminatedNCT02568007Phase 4Results posted
- Altering Activation Patterns Post-strokeCompletedNCT02418949Not applicableResults posted
- Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute MigraineCompletedNCT02389829Phase 4Results posted
- Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen PlanusCompletedNCT02329600Phase 3Results posted
- A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal MicroscopyCompletedNCT02308501Phase 4Results posted
- A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.CompletedNCT02295280Not applicableResults posted
- Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD.CompletedNCT02185131Phase 2Results posted
- Histamine Glutamate Antagonism in StrokeCompletedNCT02142712Phase 2Results posted
- Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity LevelsCompletedNCT02136420Phase 4Results posted
- Study of Promethazine for Treatment of Diabetic GastroparesisTerminatedNCT02130622Phase 2Results posted
- Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple SclerosisCompletedNCT02040298Phase 2Results posted
- Diphenhydramine as an Adjunctive Sedative in Patients on Chronic OpioidsCompletedNCT01967433Phase 4Results posted
- Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal VolunteersCompletedNCT01888497Phase 3Results posted
- Diphenhydramine for Acute MigraineCompletedNCT01825941Phase 4Results posted
- Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing ColonoscopyCompletedNCT01769586Not applicableResults posted
- A Trial to Explore Symptomatic Therapy for Application Site Reaction to SPM962 in Healthy SubjectCompletedNCT01737931Phase 1Results posted
- A Study to Evaluate the Efficacy of Lastacaft® Compared to Pataday™ and Placebo in Patients With Acute Allergic ConjunctivitisCompletedNCT01732757Phase 4Results posted
- Pilot Study on the Use of Artificial Tears to Treat Dry Eye in Glaucoma PatientsCompletedNCT01682460Phase 4Results posted
- A Placebo-controlled Crossover Trial Using Cyproheptadine To Treat Children With Functional Abdominal PainTerminatedNCT01675050Phase 2Results posted
- Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot StudyCompletedNCT01553318Phase 3Results posted
- Reletex Versus Standard of Care Therapy for Post-Operative Nausea Control in Patients Undergoing Foregut SurgeryCompletedNCT01510379Not applicableResults posted
- Treatment on Iatrogenic Weight Gain and Dyslipidaemia Associated With OlanzapineTerminatedNCT01491490Phase 2Results posted
- A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic ConjunctivitisCompletedNCT01470118Phase 4Results posted
- A Dose Ranging Effect of Preoperative Diphenhydramine on Postoperative Quality of Recovery After Ambulatory SurgeryCompletedNCT01451762Not applicableResults posted
- Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and FluCompletedNCT01448057Phase 3Results posted
- Meclizine as a Potential Smoking Cessation TreatmentCompletedNCT01443858Phase 2Results posted
- A Long-term Study of DE-114 Ophthalmic Solution in Patients With Allergic ConjunctivitisCompletedNCT01363713Phase 3Results posted