Drug
Glucarpidase clinical trials
- studies test it
- 13
- open now
- 1
- in phase 3
- 1
- first study started
- 1993
Keep track of what changes. Save the glucarpidase studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
13 studies that test it; most in 2008 (4)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 2000 | 1 |
| 2007 | 2 |
| 2008 | 4 |
| 2019 | 1 |
| 2021 | 3 |
| 2022 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 5
- Phase 2
- 8
- Phase 3
- 1
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 13
BTG International Inc. (3) · University College, London (2) · OHSU Knight Cancer Institute (1) · Charite University, Berlin, Germany (1) · Nordic Society for Pediatric Hematology and Oncology (1) · National Cancer Institute (NCI) (1) · Assistance Publique - Hôpitaux de Paris (1) · Fox Chase Cancer Center (1)
Often tested with
Tested in the same studies.
Methotrexate (3) · Gamma-Glutamyl Hydrolase (2) · Leucovorin (1)
Studies
Open first, then newest update. How each study uses glucarpidase is read from its arms, and is right about nine times in ten.
Testing it · 13
- Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System LymphomaRecruitingPhase 1Assistance Publique - Hôpitaux de ParisNCT05135858Written as Glucarpidase
- Glucarpidase After High-Dose Methotrexate in Patients With OsteosarcomaCompletedEarly Phase 1OHSU Knight Cancer InstituteNCT03960177Written as Glucarpidase
- A Phase I/II Study to Investigate the Use of VORAXAZE™ As Intended Intervention in Patients with CNSLCompletedPhase 1/2Charite University, Berlin, GermanyNCT04841434Written as Voraxaze Injectable Product
- Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNSTerminatedPhase 2Fundacion CRIS de Investigación para Vencer el CáncerNCT05022797Written as Glucarpidase 1000 UNT [Voraxaze]
- HM-178: Assessing Methods for Improvement in Methotrexate Toxicity Management and Detection of Central Nervous System Involvement of Aggressive LymphomaSuspendedPhase 2Fox Chase Cancer CenterNCT04668768Written as Glucarpidase
- Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without VoraxazeCompletedPhase 1BTG International Inc.NCT00634504Written as glucarpidase, high-dose methotrexate, leucovorin
- Glucarpidase Effect on Severe Delayed HDM-clearance in Children Treated With High-dose Mtx in ALLCompletedPhase 3Nordic Society for Pediatric Hematology and OncologyNCT01305655Written as Glucarpidase
- Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?TerminatedPhase 2University College, LondonNCT02022358Written as Glucarpidase
- Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal MethotrexateCompletedNot applicableNational Cancer Institute (NCI)NCT00018967Written as glucarpidase
- High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in OsteosarcomaTerminatedPhase 2BTG International Inc.NCT00634322Written as glucarpidase
- Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate ClearanceCompletedPhase 2BTG International Inc.NCT00219791Written as glucarpidase (50 Units/kg)
- Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System LymphomaCompletedPhase 1/2University College, LondonNCT00727831Written as glucarpidase
- Voraxaze for Delayed Methotrexate ClearanceTerminatedPhase 1/2M.D. Anderson Cancer CenterNCT00424645Written as Voraxaze (Glucarpidase)