Esketamine: all 235 studies that test it
Page 1 of 3. Open to participants first (79), then studies with results posted, then the rest; newest registration first within each.
- Intravenous Ketamine for Acute Suicidal Crisis and Psychiatric Hospital Length of StayNot yet recruitingNCT07888933Phase 2
- Perioperative Esketamine Safety and Efficacy in Reducing Postoperative ENDometriosis PAIN (the ENDPAIN Trial): a Randomized Controlled Trial.Not yet recruitingNCT07881562Phase 4
- Intranasal Dexmedetomidine Combined With Esketamine for Emergence Quality After Suspension LaryngoscopyNot yet recruitingNCT07880938Not applicable
- Propofol or Esketamine: Tracheal Intubation ComparisonNot yet recruitingNCT07847255Phase 4
- Brain Activity and Changes in Consciousness During General AnesthesiaNot yet recruitingNCT07836205Phase 4
- The Effect of Intraoperative Infusion of Esketamine on Cholestatic Pruritus in Patients Undergoing Hepatobiliary SurgeryNot yet recruitingNCT07760740Not applicable
- Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric GastroscopyNot yet recruitingNCT07748884Phase 4
- Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.Not yet recruitingNCT07736352Not applicable
- A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant DepressionRecruitingNCT07716098Phase 3
- Esketamine Versus Sufentanil for Sedation in Patients Undergoing ERCPNot yet recruitingNCT07702240Not applicable
- The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline AnesthesiaNot yet recruitingNCT07699523Not applicable
- The Effect of Esketamine on Postoperative Cognitive Function in Elderly Patients Undergoing Oral and Maxillofacial SurgeryNot yet recruitingNCT07665099Not applicable
- The Effects of Different Anesthetics on the Brain's Neural NetworksNot yet recruitingNCT07644663Phase 4
- The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Open Thyroid SurgeryNot yet recruitingNCT07625826Not applicable
- Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive ImpairmentNot yet recruitingNCT07610343Phase 4
- The Effect of Intraoperative Esketamine Infusion on Pruritus in Elderly Surgical PatientsNot yet recruitingNCT07597486Not applicable
- Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After SurgeryNot yet recruitingNCT07576543Phase 4
- Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After SurgeryNot yet recruitingNCT07576517Phase 4
- Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in ChildrenNot yet recruitingNCT07570160Phase 4
- The Effect of a Single Intravenous Injection of Esketamine During Cesarean Section on Postoperative Pruritus in Patients With Intrahepatic Cholestasis of PregnancyNot yet recruitingNCT07560722Not applicable
- Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic SurgeryNot yet recruitingNCT07374458Not applicable
- Effect of Esketamine on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Severe DepressionNot yet recruitingNCT07374211Not applicable
- Effect of Continuous Intraoperative Esketamine Infusion on Perioperative Negative Emotions in Breast Cancer Surgery Patients With Mild-to-Severe DepressionNot yet recruitingNCT07374198Not applicable
- Effect of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer SurgeryNot yet recruitingNCT07367542Not applicable
- The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavioral Changes in Children With Autism Spectrum DisorderRecruitingNCT07324057Not applicable
- Effect of Esketamine on Postoperative Sleep in Postmenopausal WomenRecruitingNCT07315074Not applicable
- Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of RecoveryRecruitingNCT07308756Phase 4
- Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic StudyRecruitingNCT07247968Early Phase 1
- A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderRecruitingNCT07227454Phase 3
- The Effect of Esketamine Combined With Dexmedetomidine on Postoperative Recovery Quality in Patients Undergoing Thoracoscopic SurgeryEnrolling by invitationNCT07125573Not applicable
- Esketamine Versus Crisis Response Planning Versus Enhanced Treatment as Usual for Suicide Prevention: A Pragmatic Randomized Trial in a Brazilian Municipality (SAVE)RecruitingNCT07120477Phase 4
- Efficacy and Safety of S-ketamine in Elderly Patients Undergoing Non-cardiac Surgery: a RCT（ESSENCE）Not yet recruitingNCT07063108Phase 4
- Etomidate and Esketamine on Postoperative Pain After Tonsillectomy Undergoing ChildrenNot yet recruitingNCT07062601Not applicable
- Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal SurgeryNot yet recruitingNCT06958393Phase 4
- Esketamine Combined With PRF of DRG for Acute/Subacute Zoster-associated PainNot yet recruitingNCT06914206Not applicable
- Esketamine Combined With PRF for Trigeminal Postherpetic NeuralgiaNot yet recruitingNCT06914180Not applicable
- Esketamine Combined Pregabalin and Duloxetine for Postherpetic NeuralgiaRecruitingNCT06896994Not applicable
- Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal NeuralgiaRecruitingNCT06890897Not applicable
- Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac SurgeryRecruitingNCT06859892Phase 4
- Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General AnesthesiaRecruitingNCT06853431Phase 4
- Effects of Esketamine on Oxygenation and Quality of Recovery in Patients Undergoing Thoracoscopic SurgeryNot yet recruitingNCT06822088Phase 4
- Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT)RecruitingNCT06817239Not applicable
- Efficacy of Esketamine for Patients With Irritable Bowel SyndromeRecruitingNCT06788444Not applicable
- Personalized DBS Targeting for Treating DepressionRecruitingNCT06784388Early Phase 1
- Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac ArrestRecruitingNCT06744361Phase 2
- PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence StudyRecruitingNCT06713616Phase 3
- Effects of Esketamine on Postoperative Behavioral Changes in Children Undergoing Tonsillectomy and/or AdenoidectomyRecruitingNCT06579937Phase 4
- Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's DiseaseRecruitingNCT06543563Not applicable
- Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord InjuryNot yet recruitingNCT06531837Not applicable
- Effects of Esketamine on Consciousness-related Brain Network Characteristics in Patients With Prolonged Disorders of ConsciousnessRecruitingNCT06473285Not applicable
- Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU PatientsNot yet recruitingNCT06468436Not applicable
- To Investigate the Effect of Esketamine Hydrochloride on Pulmonary ComplicationsRecruitingNCT06467513Phase 4
- Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal SurgeryRecruitingNCT06451627Not applicable
- Effects of Esketamine on Recovery of Consciousness After Propofol AnesthesiaRecruitingNCT06430645Not applicable
- Effect of Dexmedetomidine and Esketamine on Catheter-related Bladder DiscomfortRecruitingNCT06399185Phase 4
- Effect of Esketamine on Conscious State in Patients With pDoCRecruitingNCT06389344Not applicable
- ED50 of Esketamine for Laser Treatment in ChildrenNot yet recruitingNCT06294639Not applicable
- Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant DepressionRecruitingNCT06278779Phase 4
- Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve GastrectomyNot yet recruitingNCT06199011Not applicable
- Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT StudyRecruitingNCT06161805Phase 3
- Esketamine Combined With Pregabalin on CPSP in Spinal Patients.Not yet recruitingNCT06117917Phase 2/3
- Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in PatientsRecruitingNCT06108830Not applicable
- Positioning of Esketamine Treatment in the Real-world Management of DepressionRecruitingNCT06103760Phase 4
- Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm OutcomesRecruitingNCT06087510Phase 4
- Effect of Esketamine on Reducing Postoperative Anxiety and Depression in Adolescent PatientsNot yet recruitingNCT06073015Early Phase 1
- The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.RecruitingNCT05973851Phase 3
- Effect of Quadratus Lumborum Block With Compound Lidocaine and Esketamine on Pain After Colorectal SurgeryNot yet recruitingNCT05964985Not applicable
- Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative SedationRecruitingNCT05925283Phase 4
- Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With HypospadiasRecruitingNCT05922605Phase 4
- Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock PatientsRecruitingNCT05839366Phase 3
- Effects of Epidural Labor Analgesia With Esketamine on the Incidence of Postpartum Depression in ParturientsRecruitingNCT05826327Phase 4
- Analgesic Effect of Esketamine in DCSB in Adultscontrolled StudyNot yet recruitingNCT05603975Not applicable
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment FailureRecruitingNCT05603104Phase 3
- Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With DepressionRecruitingNCT05450432Phase 4
- The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain InjuryRecruitingNCT05095857Phase 4
- Safety and Efficacy Evaluation of S (+) - Ketamine in ChildrenEnrolling by invitationNCT04834427Phase 4
- Imaging Neural Correlates of Ketamine Using PET/MRRecruitingNCT04587778Phase 1
- Effect of Esketamine on Postoperative Depression、Gut Microbiota、Bispectral Index Data of Depression Patients Undergoing Breast Cancer Operation (ESPOD-BI)RecruitingNCT04303325Phase 4
- Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity SurgeryRecruitingNCT03756961Not applicable
- Esketamine Induction Intubation in ICU Patients.CompletedNCT05464979Early Phase 1Results posted
- A Long-Term Extension Study for Participants With Treatment-resistant Major Depressive Disorder Who Are Continuing Esketamine Nasal Spray TreatmentCompletedNCT04829318Phase 4Results posted
- A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant DepressionCompletedNCT04599855Phase 4Results posted
- A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive DisorderCompletedNCT04338321Phase 3Results posted
- A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionCompletedNCT03434041Phase 3Results posted
- Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for SuicideCompletedNCT03185819Phase 2Results posted
- 54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideCompletedNCT03097133Phase 3Results posted
- 54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideCompletedNCT03039192Phase 3Results posted
- A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant DepressionCompletedNCT02918318Phase 2Results posted
- A Long-term Safety Study of Esketamine Nasal Spray in Treatment-resistant DepressionCompletedNCT02782104Phase 3Results posted
- A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant DepressionCompletedNCT02497287Phase 3Results posted
- A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant DepressionCompletedNCT02493868Phase 3Results posted
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant DepressionCompletedNCT02422186Phase 3Results posted
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionCompletedNCT02418585Phase 3Results posted
- A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant DepressionCompletedNCT02417064Phase 3Results posted
- A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for SuicideCompletedNCT02133001Phase 2Results posted
- A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant DepressionCompletedNCT01998958Phase 2Results posted
- AM-101 in the Treatment of Post-Acute Tinnitus 1CompletedNCT01934010Phase 3Results posted
- AM-101 in the Treatment of Acute Tinnitus 2CompletedNCT01803646Phase 3Results posted
- Effect of Perioperative i.v. Low-dose S(+) KetamineCompletedNCT00354029Phase 4Results posted
- Clinical Study of Esketamine in Patients With Sepsis Undergoing Invasive Mechanical VentilationActive, not recruitingNCT07556172Phase 4