Esketamine: all 235 studies that test it

Page 3 of 3. Open to participants first (79), then studies with results posted, then the rest; newest registration first within each.

• A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant DepressionWithdrawnNCT03852160Phase 3
• Intranasal Esketamine and Fentanyl for Pain in Minor TraumaStatus unknownNCT03421275Phase 4
• A Study to Assess the Effect of Ticlopidine on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy ParticipantsCompletedNCT03298906Phase 1
• Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal HysterectomyCompletedNCT03231683Phase 2
• Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery PatientsCompletedNCT02994173Phase 4
• Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly Japanese, and Healthy Younger Adult Japanese SubjectsCompletedNCT02857777Phase 1
• A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy ParticipantsCompletedNCT02737605Phase 1
• Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug UsersCompletedNCT02682225Phase 1
• A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male ParticipantsCompletedNCT02674295Phase 1
• The Neural Mechanisms of Anesthesia and Human Consciousness (Part 6)CompletedNCT02624401Phase 4
• A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered EsketamineCompletedNCT02611505Phase 1
• A Study to Assess the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered EsketamineCompletedNCT02606084Phase 1
• S Ketamine Use in Total Abdominal HysterectomyWithdrawnNCT02543385Not applicable
• Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative PainCompletedNCT02421913Phase 4
• Inhaled Nebulised S(+)-Ketamine for Postoperative AnalgesiaWithdrawnNCT02397356Phase 4
• Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly and and Healthy Younger Adult ParticipantsCompletedNCT02345148Phase 1
• A Study to Evaluate the Absolute Bioavailability of Intranasal and Oral Esketamine and the Effects of Clarithromycin on the Pharmacokinetics of Intranasal Esketamine in Healthy ParticipantsCompletedNCT02343289Phase 1
• Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy ParticipantsCompletedNCT02228239Phase 1
• A Pharmacokinetic, Safety and Tolerability Study of Esketamine in Healthy Elderly and Adult ParticipantsCompletedNCT02129088Phase 1
• A Study to Evaluate the Effect of Intranasal Esketamine on Cognitive Functioning in Healthy SubjectsCompletedNCT02094378Phase 1
• A Study to Evaluate the Pharmacokinetics of Intranasal Esketamine Administered With and Without a Nasal Guide on the Intranasal DeviceCompletedNCT02060929Phase 1
• AM-101 in the Treatment of Post-Acute Tinnitus 2CompletedNCT02040207Phase 3
• AM-101 in the Treatment of Acute Tinnitus 3CompletedNCT02040194Phase 3
• A Study to Assess the Pharmacokinetics of Intranasally Administered Esketamine in Healthy Japanese and Caucasian VolunteersCompletedNCT01980303Phase 1
• A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy ParticipantsCompletedNCT01780259Phase 1
• A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant DepressionCompletedNCT01640080Phase 2
• Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy VolunteersCompletedNCT01506921Not applicable
• Network Dysfunction, Schizophrenia and Pharmacological Magnetic Resonance Imaging (phMRI)CompletedNCT01394757Not applicable
• The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal MidazolamCompletedNCT01275547Phase 2/3
• Comparison of Single Versus Repeat Doses of AM-101 in the Treatment of Acute Inner Ear TinnitusCompletedNCT01270282Phase 2
• The Preemptive Analgetic Potency of Low Dose S-KetamineCompletedNCT01022840Phase 3
• Efficacy of AM 101 in Patients With Acute Inner Ear TinnitusCompletedNCT00860808Phase 2
• Pharmacokinetics and Pharmacodynamics of Nasally Applied EsketamineCompletedNCT00847418Phase 1
• Anesthetics and Auditory, Visceral, and Heat Evoked PotentialsCompletedNCT00534586Phase 4
• Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic SurgeryStatus unknownNCT00532662Phase 4

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