DrugBiological
Efineptakin alfa clinical trials
Also written NT-I7 and TJ107.
- studies test it
- 29
- open now
- 1
- in phase 3
- 0
- first study started
- 2016
Keep track of what changes. Save the efineptakin alfa studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Combined with it in one product
Studies by the year they started
29 studies that test it; most in 2021 (8)
| Year | Studies |
|---|---|
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 4 |
| 2019 | 4 |
| 2020 | 4 |
| 2021 | 8 |
| 2022 | 3 |
| 2023 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 20
- Phase 2
- 12
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 18 · Other 11
Genexine, Inc. (8) · NeoImmuneTech (6) · Washington University School of Medicine (3) · TJ Biopharma Co., Ltd. (3) · Mayo Clinic (1) · Yonsei University (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Hyunseok Kang, MD (1)
Often tested with
Tested in the same studies.
Pembrolizumab (4) · Gosha-jinki-gan (3) · HPV E6/E7 DNA Vaccine GX-188E (2) · Atezolizumab (2) · Bevacizumab (1) · Tisagenlecleucel (1) · Axicabtagene ciloleucel (1) · Lisocabtagene maraleucel (1)
Studies
Open first, then newest update. How each study uses efineptakin alfa is read from its arms, and is right about nine times in ten.
Testing it · 29
- Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel)RecruitingPhase 1Washington University School of MedicineNCT07200089Written as NT-I7
- Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent GlioblastomaActive, not recruitingPhase 2Mayo ClinicNCT05465954Written as Efineptakin alfa
- Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell TherapyCompletedPhase 1NeoImmuneTechNCT05075603Written as Efineptakin alfa
- NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLCTerminatedPhase 2NeoImmuneTechNCT04984811Written as efineptakin alfa
- NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid TumorsCompletedPhase 1/2NeoImmuneTechNCT04332653Written as NT-I7
- Trial of the Combination of GX-188E Vaccination, GX-I7 and Pembrolizumab in Patients With Advanced, Resectable HPV Type 16 and/or 18 Positive Head and Neck CancerActive, not recruitingPhase 2Yonsei UniversityNCT05286060Written as GX-188E, GX-I7, Pembrolizumab
- rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-severe Lymphopenic Gliomas Following Radiation and TemozolomideActive, not recruitingPhase 1/2Washington University School of MedicineNCT03687957Written as rhIL-7-hyFc
- NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients With Progressive Multifocal LeukoencephalopathyCompletedEarly Phase 1National Institute of Neurological Disorders and Stroke (NINDS)NCT04781309Written as NT-I7
- High-Risk Skin Cancers With Atezolizumab Plus NT-I7TerminatedPhase 1/2NeoImmuneTechNCT03901573Written as NT-I7
- NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing SurgeryTerminatedPhase 1Hyunseok Kang, MDNCT04588038Written as Efineptakin alfa
- NT-I7 in Combination With Nivolumab in Advanced Gastric, Gastro-Esophageal Junction or Esophageal AdenocarcinomaTerminatedPhase 1NeoImmuneTechNCT04594811Written as NT-I7
- NT-I7 for Kaposi Sarcoma in Patients With or Without HIVTerminatedPhase 1Fred Hutchinson Cancer CenterNCT04893018Written as Efineptakin alfa
- A Study to Evaluate the Efficacy and Safety of TJ107 in Lympopenic Patients With Newly Diagnosed Glioblastoma Who Completed Standard Concurrent Chemoradiotherapy (CCRT)Active, not recruitingPhase 2TJ Biopharma Co., Ltd.NCT04600817Written as TJ107
- Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid TumorsActive, not recruitingPhase 2TJ Biopharma Co., Ltd.NCT05145907Written as TJ107 +Pembrolizumab
- Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TJ107 in Chinese Patients With Advanced Solid TumorsCompletedPhase 1/2TJ Biopharma Co., Ltd.NCT04001075Written as TJ107
- Vaccine Response With NT-I7WithdrawnPhase 1National Cancer Institute (NCI)NCT04054752Written as Recombinant human IL-7-hyFc (NT-I7)
- Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade GliomasTerminatedPhase 1Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT02659800Written as NT-I7
- A Trial of NT-I7 in COVID-19 (SPESELPIS)TerminatedPhase 1NeoImmuneTechNCT04501796Written as Double-Blind NT-I7
- GX-I7 in Combination With Bevacizumab in Recurrent Glioblastoma (GBM) PatientsActive, not recruitingPhase 2Genexine, Inc.NCT05191784Written as GX-I7
- Safety and Preliminary Efficacy Study of GX-I7 in Patients With COVID-19TerminatedPhase 1Genexine, Inc.NCT04730427Written as GX-I7
See all 29 studies that test efineptakin alfa →
Given in every arm · 2 — efineptakin alfa is usual care beside what is tested
- Phase 1 Study Evaluating Safety and Tolerability of SL-T10, GX-I7, and Pembrolizumab Triple Combination in mCRPC.Status unknownPhase 1SL VAXiGENNCT06344715Written as GX-I7
- Study of GX-I7 in Combination With Pembrolizumab in Refractory or Relapsed (R/R) TNBC Subjects(GX-I7-CA-006/KEYNOTE-899)CompletedPhase 1/2Genexine, Inc.NCT03752723Written as GX-I7
Codes
What other systems call efineptakin alfa · ClinicalTrials.gg INT001518
- MeSH (NLM) C000712767efineptakin alfaConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 3K3WC6MT6PEFINEPTAKIN ALFAConfirmed FDA, NLM
- NCI Thesaurus C151927Efineptakin alfaOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000712767 | efineptakin alfa | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 3K3WC6MT6P | EFINEPTAKIN ALFA | Confirmed FDA, NLM |
| NCI Thesaurus | C151927 | Efineptakin alfa | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.