Diuretics: all 808 studies that test it

Page 3 of 9. Open to participants first (101), then studies with results posted, then the rest; newest registration first within each.

• Mineralocorticoid Receptor and Obesity Induced Cardiovascular ComplicationsCompletedNCT01406015Not applicableResults posted
• Predicting Successful Sleep Apnea Treatment With Acetazolamide in Heart Failure PatientsCompletedNCT01377987Not applicableResults posted
• Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN)CompletedNCT01371747Phase 2Results posted
• Feasibility of an Integrated Patient Care (IPC) System Using Daily Filling PressuresCompletedNCT01370564Phase 2Results posted
• Preservation of Ovarian Function After Hematopoietic Cell TransplantTerminatedNCT01343368Phase 2Results posted
• Measurement of Kidney Blood Flow and Oxygen Levels by MRICompletedNCT01318967Not applicableResults posted
• Long-Term Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Hypertension and Kidney DiseaseCompletedNCT01309828Phase 3Results posted
• MK-0954E Study in Participants With Hypertension (MK-0954E-357)CompletedNCT01302691Phase 3Results posted
• Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained MenCompletedNCT01294319Phase 2Results posted
• Intracranial Pressure in Experimental Models of HeadacheCompletedNCT01288781Not applicableResults posted
• Pharmacodynamics and Pharmacokinetics of Empagliflozin and Torasemide in Patients With Type 2 DiabetesCompletedNCT01276288Phase 1Results posted
• The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney InjuryCompletedNCT01275729Not applicableResults posted
• A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly PeopleTerminatedNCT01259297Phase 3Results posted
• Pharmacogenomic Evaluation of Antihypertensive Responses 2CompletedNCT01203852Phase 4Results posted
• Safety and Efficacy of Chlorthalidone + Amiloride to Elderly Patients Treatment With Arterial HypertensionCompletedNCT01191450Phase 3Results posted
• A Study to Investigate the Pharmacodynamic and Pharmacokinetic Interaction Between Aliskiren and Furosemide in Patients With Heart FailureCompletedNCT01125514Phase 2Results posted
• Aldosterone and the Metabolic SyndromeCompletedNCT01103245Phase 1Results posted
• Spironolactone in Adult Congenital Heart DiseaseCompletedNCT01069510Phase 2Results posted
• The Effect of Spironolactone on Blood Pressure in Type-2 Diabetics With Resistant HypertensionCompletedNCT01062763Phase 3Results posted
• Furosemide vs Placebo for Brain RelaxationTerminatedNCT01054404Not applicableResults posted
• Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.CompletedNCT01033071Phase 3Results posted
• Idiopathic Intracranial Hypertension Treatment TrialCompletedNCT01003639Phase 2/3Results posted
• Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential HypertensionCompletedNCT00996281Phase 3Results posted
• The Effects of Decreasing the Lasix Dose on the Cardiorenal SystemCompletedNCT00982423Phase 1/2Results posted
• Aliskiren/Amlodipine/Hydrochlorothiazide (HCTZ) Versus Aliskiren/Amlodipine in US Minority Patients With Stage II Systolic HypertensionCompletedNCT00942994Phase 4Results posted
• Valsartan/Amlodipine As Compared to Losartan Treatment in Stage 2 Systolic HypertensionCompletedNCT00931710Phase 4Results posted
• Telmisartan 80mg Plus Hydrochlorothiazide 25mg First Line in Moderate or Severe HypertensionCompletedNCT00926289Phase 4Results posted
• Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart FailureTerminatedNCT00904488Phase 4Results posted
• Valsartan Intensified Primary Care Reduction of Blood Pressure StudyCompletedNCT00902304Phase 4Results posted
• Salt Loading and Thiazide Intervention StudyCompletedNCT00896389Phase 4Results posted
• Metabolic Effects of Antihypertensive Drugs on People With Metabolic Syndrome (The MEAD Study)CompletedNCT00887510Phase 4Results posted
• Clinical and Therapeutic Implications of Fibrosis in Hypertrophic CardiomyopathyCompletedNCT00879060Phase 4Results posted
• Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)CompletedNCT00871871Phase 1Results posted
• Role of Mineralocorticoid Receptor in Diabetic Cardiovascular DiseaseCompletedNCT00865124Not applicableResults posted
• Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe HypertensionCompletedNCT00847626Phase 3Results posted
• Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe HypertensionCompletedNCT00846365Phase 3Results posted
• A Translational Approach to Gitelman SyndromeCompletedNCT00822107Not applicableResults posted
• Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe HypertensionCompletedNCT00818883Phase 3Results posted
• Aliskiren HCTZ Compared to Amlodipine in Patients With Stage 2 Systolic Hypertension and Diabetes MellitusCompletedNCT00787605Phase 4Results posted
• Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-severe HypertensionCompletedNCT00765674Phase 3Results posted
• Blood Pressure Lowering of Aliskiren Hydrochlorothiazide (HCTZ) Versus Amlodipine in Stage 2 Hypertension in African AmericansCompletedNCT00739596Phase 4Results posted
• Efficacy and Safety of the Combination Aliskiren (300 mg) and Hydrochlorothiazide (25mg) to Aliskiren (300mg) Monotherapy in Patients With Staged II HypertensionCompletedNCT00705575Phase 3Results posted
• Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Compared to Valsartan Monotherapy or Hydrochlorothiazide Monotherapy in Elderly (>70) With Mild-moderate Hypertension.CompletedNCT00698646Phase 4Results posted
• Protocol to Assess the Severity of Acute Kidney InjuryCompletedNCT00673244Not applicableResults posted
• A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential HypertensionCompletedNCT00667719Phase 3Results posted
• Black Education and Treatment of Hypertension (BEAT HTN)CompletedNCT00661895Phase 4Results posted
• 18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 DiabeticsCompletedNCT00654745Phase 4Results posted
• Candesartan Effect in Second Stage Arterial HypertensionCompletedNCT00621153Phase 4Results posted
• Effect of Licorice and Hydrochlorothiazide on Plasma PotassiumCompletedNCT00605202Phase 4Results posted
• Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential HypertensionCompletedNCT00591773Phase 3Results posted
• Mechanisms of Ramipril Reduction in the Onset of Type 2 DiabetesTerminatedNCT00574834Early Phase 1Results posted
• Effect of Aldosterone on Energy Starvation in Heart FailureCompletedNCT00574119Phase 4Results posted
• Nephropathy In Type 2 Diabetes and Cardio-renal EventsCompletedNCT00535925Phase 4Results posted
• The Vascular Effects of Carvedilol Controlled Release (CR) in Abdominally Obese Hypertensive PatientsCompletedNCT00459056Phase 3Results posted
• Safety/Efficacy of Valsartan/Hydrochlorothiazide Combination Compared to Hydrochlorothiazide in Obese Hypertensive AdultsCompletedNCT00439738Phase 4Results posted
• Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and PlaceboCompletedNCT00434967Phase 3Results posted
• Combination of Olmesartan and Hydrochlorothiazide in Essential HypertensionCompletedNCT00430950Phase 3Results posted
• Use of the Combination of Olmesartan and Hydrochlorothiazide in Essential HypertensionCompletedNCT00430508Phase 3Results posted
• An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Elderly Patients With HypertensionCompletedNCT00412932Phase 4Results posted
• An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Patients With Type II DiabetesCompletedNCT00403481Phase 4Results posted
• Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive PatientsCompletedNCT00396656Phase 3Results posted
• Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs AloneCompletedNCT00391846Phase 4Results posted
• A Safety and Tolerability Study of the Combination of Aliskiren/Valsartan in Patients With High Blood Pressure, Followed by Long-term Safety and Tolerability of Aliskiren, Valsartan and Hydrochlorothiazide.CompletedNCT00386607Phase 3Results posted
• The Effects of Potassium Citrate on Bone MetabolismCompletedNCT00357331Phase 4Results posted
• Obese Hypertension Study (0954-315)CompletedNCT00289887Phase 3Results posted
• Pharmacogenomic Evaluation of Antihypertensive ResponsesCompletedNCT00246519Phase 4Results posted
• Spironolactone in Patients With Single Ventricle HeartCompletedNCT00211081Not applicableResults posted
• Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)CompletedNCT00141778Phase 2/3Results posted
• PIE II: Pharmacological Intervention in the Elderly IICompletedNCT00123955Phase 3Results posted
• Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic FunctionCompletedNCT00094302Phase 3Results posted
• Low-Dose Spironolactone in Hemodialysis Patients With Resistant HypertensionCompletedNCT07888504Phase 4
• Acetazolamide to Reduce Spinal Fluid Leaks After Spine Surgery.CompletedNCT07876713Phase 4
• Study of Antihypertensive Treatment and Cardiovascular Risk in Chinese Prehypertensive PopulationCompletedNCT07652567Not applicable
• Albumin and Furosemide for Preventing Ovarian Hyperstimulation Syndrome in ICSI PatientsCompletedNCT07568886Not applicable
• Effectiveness of Valsartan Alone vs Combination Therapy in Hypertensive Heart DiseaseCompletedNCT07544888Phase 1
• The Role of Acetazolamide in Mitigating Inflammation and Innate Immune Activation at High AltitudeActive, not recruitingNCT07517068Early Phase 1
• A Clinical Study of the Effect of MK-2828 on Rosuvastatin or Furosemide in Healthy People (MK-2828-005)CompletedNCT07431866Phase 1
• Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Management of Renal StonesCompletedNCT07336485Not applicable
• Unmitigated Aldosterone Signaling During Standard Clinical MRA DosingActive, not recruitingNCT07281014Phase 4
• Study to Compare Bioavailability and Pharmacokinetics of a Novel Furosemide Regimen Administered Subcutaneously Versus the Same Dose (80 mg) Administered Intravenously in Healthy VolunteersCompletedNCT07269496Phase 1
• Pharmacokinetics, Safety and Tolerability of Concurrent Doses of BIA 5-1058 and FurosemideCompletedNCT07173738Phase 1
• Bioavailability and Bioequivalence Study of Extended Release Torsemide and SpironolactoneCompletedNCT07046975Phase 3
• Bioavailability and Bioequivalence Study of ER Torsemide and Spironolactone FDC Tablet in Healthy SubjectsCompletedNCT07015671Phase 3
• Efficacy of Bumetanide in Children With Autism Spectrum Disorder Guided by Peripheral Blood Biomarkers and Machine Learning ModelsCompletedNCT07005414Phase 2
• Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of SaruparibActive, not recruitingNCT06899061Phase 1
• Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep ApneaActive, not recruitingNCT06776432Phase 2
• The Role of Furosemide Stress Test in the Intensive Care ClinicCompletedNCT06765031Not applicable
• A Crossover Study of Patients With HF to Compare Natriuretic Effects of IR Torsemide vs. ER Torsemide Over 12 HrsWithdrawnNCT06708611Phase 4
• Bioequivalence Study of Spironolactone Tablets in Healthy SubjectsCompletedNCT06579053Phase 1
• HighCycle Study: Effect of Acetazolamide on Acute Mountain Sickness in Women Compared to MenCompletedNCT06499727Phase 4
• HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to MenCompletedNCT06498531Phase 4
• HighCycle: Effect of Acetazolamide on Pulmonary Artery Pressure in Women Compared to MenCompletedNCT06498505Phase 4
• Natriuretic Effect of Amiloride in Relation to the Alpha Adducin Gene (ADD-AMI) RS4961 VariantCompletedNCT06416735Phase 3
• Pharmacogenetics of Torasemide and Spironolactone in Hypertension TreatmentCompletedNCT06413082Phase 3
• Acamprosate and Methazolamide for Essential TremorWithdrawnNCT06312800Phase 2
• Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.CompletedNCT06287580Early Phase 1
• The Impact of Inhaled Furosemide and Perorally Administered Levodropropizine on Dyspnea in Patients With Respiratory DiseasesStatus unknownNCT06252454Phase 2/3
• The AXIS Study: the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in RetinoschisisCompletedNCT06114537Phase 2
• Managing Opioid Related Sleep Apnea With AcetazolamideCompletedNCT06043830Phase 2
• Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure.CompletedNCT06024889Phase 1/2

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