Cyclooxygenase Inhibitors: all 2,871 studies that test it

Page 2 of 29. Open to participants first (296), then studies with results posted, then the rest; newest registration first within each.

• Aspirin for Patients With Metabolic Dysfunction-Associated Steatotic Liver DiseaseRecruitingNCT06935994Phase 2
• Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomized-controlled Orphan Drug Platform Trial for Orodental Sequelae (Reverse-fibrose)RecruitingNCT06912763Phase 2
• Topical Diclofenac for Prevention of Radiation-induced DermatitisRecruitingNCT06905561Not applicable
• Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal CancerRecruitingNCT06903858Phase 2
• Non Steroidal Anti-inflammatory Drugs in the Prevention of Bone Pain Flares After Palliative RadiotherapyNot yet recruitingNCT06903585Phase 2
• A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving ChemotherapyRecruitingNCT06866964Phase 2
• NSAID Use for Treating Dysmenorrhea and Preventing Chronic Pelvic Pain (NSAID HEAL)RecruitingNCT06861920Phase 4
• Oral Ketorolac for IUD Pain ReductionEnrolling by invitationNCT06853327Phase 2
• Antimicrobial Effect of Curcumin Versus Chlorohexidine on Oral MicrobiomeNot yet recruitingNCT06847984Not applicable
• The Effect of Curcumin on Inflammatory Markers in Hemodialysis PatientsNot yet recruitingNCT06829186Phase 2
• Comparison of the Efficacy of Diclofenac Sodium and Subcutaneous 5% Dextrose Injection in Low Back Pain.Enrolling by invitationNCT06829030Phase 1/2
• Ketorolac at Lower Doses for Analgesic Pain Control in ICU: A Pilot Feasibility StudyRecruitingNCT06819956Phase 3
• Aspirin in Acute Pneumonia in the Elderly: a Multicenter, Double-blind, Randomized, Placebo-controlled Trial.Not yet recruitingNCT06774846Phase 3
• Genotype-Guided Abbreviated DAPT Versus Un-Guided De-escalation Therapy in Patients With ACS and HBRNot yet recruitingNCT06763744Phase 4
• Safety and Effectiveness of Early Aspirin Administration After Mitral Valve RepairRecruitingNCT06738992Phase 4
• Non-steroidal Anti-inflammatory Drugs in PleurodesisRecruitingNCT06731647Phase 2
• Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent ImmunotherapyRecruitingNCT06731270Phase 2
• Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical SurgeriesNot yet recruitingNCT06729047Phase 1/2
• Levonorgestrel-piroxicam Versus Ulipristal Acetate for Emergency ContraceptionRecruitingNCT06727734Phase 3
• Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent ImplantationRecruitingNCT06723145Phase 4
• Celecoxib for Prevention of Progression in Peutz-Jeghers SyndromeRecruitingNCT06722534Not applicable
• Effect of Genotype-Guided Oral P2Y12 Inhibitor Selection vs Conventional Clopidogrel Therapy in Symptomatic ICADRecruitingNCT06714526Not applicable
• Amniotic Suspension Allograft Injection for Knee OsteoarthritisRecruitingNCT06704893Phase 3
• Stony Brook Medicine Anti-Inflammatory TrialNot yet recruitingNCT06699966Phase 4
• Non-Steroidal Anti-Inflammatory Drugs in Acute MyocarditisRecruitingNCT06686862Phase 3
• ASpirin Use and stAtin Strategy for Primary Prevention in Severe Coronary Calcium Score on Computed TomographyRecruitingNCT06676280Phase 4
• Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids TrialRecruitingNCT06671002Phase 4
• Combined Ketorolac and Lidocaine Paracervical Block for Office HysteroscopyEnrolling by invitationNCT06653400Phase 1
• Efficacy and Safety of Parecoxib vs. Indomethacin in Preventing Post-ERCP PancreatitisNot yet recruitingNCT06623513Phase 2
• Bioequivalence of Two Formulations of Parecoxib in Healthy Volunteers Under Fasting ConditionsNot yet recruitingNCT06600282Phase 4
• Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral CurcuminRecruitingNCT06595355Phase 2/3
• Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell DiseaseNot yet recruitingNCT06579703Phase 4
• Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid HemorrhageRecruitingNCT06579274Phase 2
• The Effects of Patient and Visit Characteristics on Health Outcomes in Knee OsteoarthritisRecruitingNCT06574191Not applicable
• Single-dose Prophylactic INdomethacin in Extremely Preterm InfantsNot yet recruitingNCT06572917Phase 2
• Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)RecruitingNCT06548971Phase 3
• Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic DiseaseRecruitingNCT06541691Not applicable
• Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood DisturbanceRecruitingNCT06531863Early Phase 1
• Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord InjuryNot yet recruitingNCT06531837Not applicable
• Effect of Low Molecular Heparin on Pregnancy Outcome With Protein S DeficiencyNot yet recruitingNCT06531525Phase 2
• Short Versus Long Antiplatelet Therapy After TAVIRecruitingNCT06518317Phase 3
• Ketorolac Effects on Post-operative Pain and Lumbar FusionRecruitingNCT06513208Phase 4
• An Bioequivalence Study of Loxoprofen Sodium Patches in Healthy VolunteersNot yet recruitingNCT06510413Phase 1
• Celecoxib for ENT Pain ManagementRecruitingNCT06505187Phase 2
• Comparing the Difference in Pain Control in the Pediatric General Surgery Population: to Alternate or Combine Acetaminophen and Ibuprofen?Not yet recruitingNCT06505148Phase 4
• Evaluation of the Effect of Intra-ligamentary Injection of Diclofenac Potassium Versus Articaine on Anaesthetic Efficacy in Mandibular Molars With Symptomatic Irreversible Pulpitis.Not yet recruitingNCT06500871Early Phase 1
• Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCTNot yet recruitingNCT06498440Phase 4
• The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue MorbidityRecruitingNCT06494878Phase 3
• Pain Control After Lumbar Spine FusionEnrolling by invitationNCT06484192Phase 4
• Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean SectionRecruitingNCT06479122Phase 4
• TPO-RA Treatment on Immune Tolerance Induction of ITP Patients With Sustained Platelet Recovery After Treatment TerminationRecruitingNCT06478537Phase 2
• Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIALRecruitingNCT06468202Phase 4
• IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary SyndromeRecruitingNCT06451198Phase 4
• APPLE: Aspirin to Prevent Pregnancy Loss and PreeclampsiaRecruitingNCT06408181Phase 3
• The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in CombinationNot yet recruitingNCT06401499Phase 4
• Use of 81 vs 325mg of ASA in Treatment of BCVINot yet recruitingNCT06383650Early Phase 1
• Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic SurgeriesRecruitingNCT06379425Phase 4
• NonNarcotic Pain Control in Percutaneous Needle Tenotomy of ElbowRecruitingNCT06373978Phase 4
• Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) ArthritisEnrolling by invitationNCT06359665Phase 1
• Intracutaneous Sterile Water and Diclofenac Sodium Injections in Renal ColicNot yet recruitingNCT06342648Not applicable
• SPI-1005 in Adults Receiving Cochlear ImplantRecruitingNCT06340633Phase 2
• Bioequivalence Study of Generic Celecoxib 200 mg CapsulesNot yet recruitingNCT06337422Phase 1
• Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency DepartmentNot yet recruitingNCT06315920Phase 3
• Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17Not yet recruitingNCT06312761Phase 1/2
• Treatment With Aspirin After Preeclampsia: TAP TrialRecruitingNCT06281665Phase 4
• Highest Efficacy of Dual Antiplatelet Therapy After Carotid Artery Stenting in High Bleeding Risk PatientsRecruitingNCT06276374Not applicable
• Optimal Treatment of Acute Skeletal Muscle InjuryNot yet recruitingNCT06274151Not applicable
• Treatment of Topical Ketorolac Gel in Acute Gouty FlareNot yet recruitingNCT06273813Phase 1
• A Combination of Ibuprofen With Curcumin Covered With Liquorice Root Supplementation in the Management of Postoperative Dental Pain in AdultsNot yet recruitingNCT06269406Not applicable
• Low Dose Aspirin for Prevention of Early Pregnancy LossRecruitingNCT06261203Not applicable
• Aspirin Dose Comparison in Elderly PCI Patients: 30mg vs. 75mg in Acute Coronary SyndromeRecruitingNCT06254391Phase 2
• Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee OsteoarthritisRecruitingNCT06245109Phase 4
• The Antimicrobial Potential of Diclofenac Sodium as an Intracanal MedicamentRecruitingNCT06207253Phase 2/3
• Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma PatientsRecruitingNCT06201676Phase 4
• The Effect of Aspirin on Recurrent Acute PancreatitisRecruitingNCT06185621Not applicable
• Daily Aspirin Treatment After PreeclampsiaRecruitingNCT06168461Early Phase 1
• Effects of Antiplatelet and Antioxidant Agents on Drusen Progression: A Pilot, Prospective Cohort StudyRecruitingNCT06165068Phase 3
• Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal PainRecruitingNCT06160778Phase 3
• Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone DiseaseRecruitingNCT06158620Phase 1/2
• Comparision Between Paracetamol and Ibuprofen in Closure of Patent Ductus ArteriosusNot yet recruitingNCT06152796Phase 2
• Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)RecruitingNCT06150898Phase 2
• Lovenox With Aspirin in Thawed Blastocyst TransferRecruitingNCT06133803Phase 4
• PFA 100 Evaluation and Reference Interval HOACNYEnrolling by invitationNCT06100510Phase 4
• Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar DepressionRecruitingNCT06088732Phase 1/2
• Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 DiabetesRecruitingNCT06082063Phase 3
• Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint PainRecruitingNCT06081101Early Phase 1
• Curcumin Supplementation in Cervical CancerRecruitingNCT06080841Not applicable
• Study of the Protective Effect of Low-dose Aspirin on Renal Function in Patients With Early Diabetic NephropathyNot yet recruitingNCT06068439Phase 2/3
• Dexketoprofen and Ibuprofen in Long Bone FracturesRecruitingNCT06060236Phase 4
• A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)RecruitingNCT06055894Not applicable
• Contribution of UGT2B17 to the Pharmacokinetics of DiclofenacRecruitingNCT06053411Early Phase 1
• Assessing Ketorolac (Toradol) at Oocyte RetrievalRecruitingNCT06026553Phase 1
• Effect of Hebal and Synthetic Medicamentss on Enterococcus FeacalisNot yet recruitingNCT06006663Phase 2/3
• NSAID Injection Versus Corticosteroid Injection for Basilar Thumb ArthritisRecruitingNCT05992883Phase 3
• The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measurements, Concentrations of Thyroid Hormones, Anti-TPO, and Systemic Inflammation in Plasma and NFK-B in Peripheral Blood Mononuclear Cells in Patients With HashimatoNot yet recruitingNCT05975866Not applicable
• Role of Curcumin in Paclitaxel Induced PNNot yet recruitingNCT05966441Phase 2
• Efficacy, Safety and Tolerability Study of Meloxicam Injection in Subjects After Abdominal SurgeryNot yet recruitingNCT05950152Phase 2
• Concomitant Curcumin Palliative Radiotherapy in Advanced Cervical Cancer TrialRecruitingNCT05947513Not applicable
• Randomized Comparison of Morning Versus Bedtime Administration of Aspirin: A Cardiovascular Circadian Chronotherapy (C3) TrialRecruitingNCT05932472Phase 4
• Aspirin for Postpartum Patients With PreeclampsiaRecruitingNCT05924971Phase 2

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