Cyclooxygenase Inhibitors: all 2,871 studies that test it

Page 4 of 29. Open to participants first (296), then studies with results posted, then the rest; newest registration first within each.

• Phase II Study of Ovulation in Obese WomenCompletedNCT06306131Phase 2Results posted
• Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative PainCompletedNCT05982392Phase 2/3Results posted
• Bioavailability and Safety Study Comparing Two Dose Levels of AMZ001 and One Dose Level of Diclofenac Sodium 1% Gel in Healthy ParticipantsCompletedNCT05968482Phase 1Results posted
• Postpartum ASA and NT-proBNPCompletedNCT05889468Phase 4Results posted
• A Bioequivalence Study of Two Ibuprofen Arginine Granules 400 mg Formulations Under Fasting and Fed Conditions in Chinese Healthy Adult SubjectsCompletedNCT05737069Phase 1Results posted
• Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven DaysCompletedNCT05695352Phase 2Results posted
• Rectal Indomethacin vs Intravenous KetorolacCompletedNCT05664074Phase 4Results posted
• Anti-Platelets in Chronic Obstructive Pulmonary DiseaseCompletedNCT05567562Phase 2Results posted
• A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to PlaceboCompletedNCT05485805Phase 3Results posted
• Evaluation the Effects of Various Treatments on RZL-012-Induced Adverse EventsCompletedNCT05476679Phase 1/2Results posted
• Safety and Pharmacokinetics of N1539 in Children 2 to <17 Years of Age Following SurgeryTerminatedNCT05315479Phase 4Results posted
• Meloxicam for Pain Management After Total Joint Arthroplasty (TJA)CompletedNCT05291598Phase 3Results posted
• Dosing of Ketorolac Impacts Post-cesarean paiN manaGemenet (KING)CompletedNCT05248984Phase 4Results posted
• Periarticular Bupivacaine + Meloxicam ER Solution Versus Standard Practice During Total Knee ArthroplastyCompletedNCT05188053Phase 4Results posted
• A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy ParticipantsCompletedNCT05093790Phase 2Results posted
• Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 PatientsTerminatedNCT05077969Phase 2Results posted
• Nonopioid Pain Control Regimen After Arthroscopic Hip ProceduresCompletedNCT05076110Phase 4Results posted
• A Study of Soticlestat With Itraconazole and Mefenamic Acid in Healthy AdultsCompletedNCT05064449Phase 1Results posted
• PET Imaging of Cyclooxygenase in Multiple SclerosisTerminatedNCT05062083Phase 2Results posted
• ASPIRED-XT: ASPirin Intervention for the REDuction of Colorectal Cancer Risk -EXTensionActive, not recruitingNCT05056896Early Phase 1Results posted
• A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.CompletedNCT05026320Phase 2Results posted
• WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?CompletedNCT04990791Phase 4Results posted
• NSAIDs vs Opioids for Post-op Pain in Supracondylar Humerus FracturesTerminatedNCT04905563Phase 4Results posted
• A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal PainCompletedNCT04860804Phase 4Results posted
• An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute HeadacheCompletedNCT04860713Phase 4Results posted
• PROUD Study - Preventing Opioid Use DisordersTerminatedNCT04766996Phase 4Results posted
• Arginine Supplementation to Improve Cardiovascular and Endothelial Function After NSAID TreatmentCompletedNCT04765644Phase 4Results posted
• Intramuscular Ketorolac at Two Single-Dose RegimensCompletedNCT04763876Phase 4Results posted
• Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral FracturesCompletedNCT04761302Phase 4Results posted
• Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate CancerCompletedNCT04731844Phase 2Results posted
• A Trial of Bardoxolone Methyl in Patients With CKD at Risk of Rapid Progression (MERLIN)CompletedNCT04702997Phase 2Results posted
• OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant PatientsCompletedNCT04694300Phase 4Results posted
• SPI-1005 for the Treatment of Meniere's DiseaseCompletedNCT04677972Phase 3Results posted
• The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDFTerminatedNCT04650893Phase 3Results posted
• Acute Low Back Pain. Topical Diclofenac and Oral Ibuprofen.CompletedNCT04611529Phase 4Results posted
• Adjunctive Acetylsalicylic Acid and Ibuprofen for TuberculosisTerminatedNCT04575519Phase 2Results posted
• Opioid-Free Anesthetic for TonsillectomyTerminatedNCT04528173Phase 4Results posted
• COVID-19 Positive Outpatient Thrombosis Prevention in Adults Aged 40-80TerminatedNCT04498273Phase 3Results posted
• Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell CarcinomaTerminatedNCT04495894Phase 2Results posted
• BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19)CompletedNCT04494646Phase 2Results posted
• SPI-1005 Treatment in Severe COVID-19 PatientsCompletedNCT04483973Phase 2Results posted
• Multimodal Pain Management After Robotic-Assisted Total Laparoscopic HysterectomyCompletedNCT04429022Phase 3Results posted
• Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy AdultsCompletedNCT04425902Phase 1Results posted
• Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE)TerminatedNCT04402385Phase 2Results posted
• Aspirin for Prevention of Venous Thromboembolism Among Ovarian Cancer Patients Receiving Neoadjuvant ChemotherapyCompletedNCT04352439Phase 4Results posted
• Study to Collect Information on How Well the Study Drug Naproxen Sodium Tablets Works Compared to Hydrocodone/Acetaminophen Tablets in Order to Relieve Pain in Participants Experiencing Moderate to Severe Pain After Having Their Wisdom Teeth RemovedCompletedNCT04307940Phase 4Results posted
• Human Cerebral Blood Flow RegulationCompletedNCT04265053Early Phase 1Results posted
• Multimodal Pain Study in Free Flap PatientsCompletedNCT04246697Phase 4Results posted
• Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL SurgeryCompletedNCT04246554Phase 3Results posted
• Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus SurgeryCompletedNCT04246541Phase 3Results posted
• Trial of Indomethacin in Chronic PancreatitisCompletedNCT04207060Phase 1/2Results posted
• Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant UsersCompletedNCT04205929Phase 4Results posted
• Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck CancerTerminatedNCT04162873Phase 2Results posted
• Mechanistic Characterization of Uterine PainCompletedNCT04145518Phase 4Results posted
• Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth RemovedCompletedNCT04132336Phase 2Results posted
• Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized TrialTerminatedNCT04115644Phase 4Results posted
• Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 TrialsTerminatedNCT04115098Phase 2Results posted
• Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent RemovalCompletedNCT04112160Phase 2Results posted
• Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory MelanomaTerminatedNCT04093323Phase 2Results posted
• Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast CancerCompletedNCT04081389Phase 1Results posted
• Low Doses of Aspirin in the Prevention of PreeclampsiaCompletedNCT04070573Phase 3Results posted
• The ARIES HeartMate 3 Pump IDE StudyCompletedNCT04069156Not applicableResults posted
• Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial PainCompletedNCT04066426Phase 4Results posted
• Symptomatic Management of Lyme ArthritisTerminatedNCT04038346Phase 3Results posted
• Aspirin for the Treatment of Nonalcoholic Fatty Liver DiseaseCompletedNCT04031729Phase 1/2Results posted
• A Multimodal Analgesia Protocol Adapted for Ambulatory SurgeryCompletedNCT04015908Phase 4Results posted
• Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDASTerminatedNCT04015596Phase 4Results posted
• ICE-T Pain Regimen for Total Laparoscopic HysterectomyCompletedNCT03987022Phase 4Results posted
• Oral Ketorolac for Arthroscopic Rotator Cuff RepairCompletedNCT03967847Phase 3Results posted
• Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese GravidaCompletedNCT03961360Phase 2/3Results posted
• A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCONTerminatedNCT03918447Phase 3Results posted
• Subacromial Methylprednisolone Versus Ketorolac for Shoulder ImpingementTerminatedNCT03913702Phase 2Results posted
• Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal ConditionsTerminatedNCT03912428Phase 1Results posted
• Study of Post-Herniorrhaphy Non-opioid MMA RegimensCompletedNCT03907176Phase 3Results posted
• Role of ASpirin in Placental and Maternal Endothelial Cell Regulation IN Pre-eclampsiaCompletedNCT03893630Phase 2Results posted
• Study of Ketorolac Versus Opioid for Pain After EndoscopyCompletedNCT03888144Phase 4Results posted
• Naproxen Sodium/Acetaminophen Proof of Concept Dosing StudyCompletedNCT03879408Phase 2Results posted
• The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to EndotoxinCompletedNCT03869268Phase 4Results posted
• A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain.CompletedNCT03861611Phase 4Results posted
• Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing UrethroplastyCompletedNCT03859024Phase 4Results posted
• Aspirin for Exercise in Multiple Sclerosis (ASPIRE)CompletedNCT03824938Phase 3Results posted
• Nonopioid Analgesia After Anterior Cruciate Ligament ReconstructionCompletedNCT03818932Phase 2/3Results posted
• Nonopioid Analgesia After Rotator Cuff RepairCompletedNCT03818919Phase 2Results posted
• IV Ketorolac on Platelet Function Post-Cesarean DeliveryCompletedNCT03805607Phase 4Results posted
• Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third MolarsCompletedNCT03785756Phase 3Results posted
• Pain Control Following Sinus SurgeryCompletedNCT03783702Phase 4Results posted
• Inflammation and Daily Life StudyCompletedNCT03771612Early Phase 1Results posted
• Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius FractureTerminatedNCT03749616Phase 4Results posted
• An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)TerminatedNCT03749447Phase 3Results posted
• Actual Use and Compliance Study Of Ibuprofen 600 Mg Immediate Release/Extended Release Tablets In At-Risk OTC ConsumersTerminatedNCT03722238Phase 3Results posted
• Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus ArteriosusTerminatedNCT03701074Phase 2Results posted
• NSAIDs vs. Coxibs in the Presence of AspirinTerminatedNCT03699293Phase 4Results posted
• Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder PainCompletedNCT03697720Phase 4Results posted
• Knee Injection RCTTerminatedNCT03694821Phase 4Results posted
• Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma SurgeryCompletedNCT03693404Phase 4Results posted
• A Study to Compare the Amount of Meloxicam in the Blood When it is Taken as Capsules or as TabletsCompletedNCT03684265Phase 1Results posted
• Increased Ketorolac Administration After Cesarean Section and Its Effect on Opioid Use: a Randomized Control TrialCompletedNCT03678675Phase 3Results posted
• Inflammatory Markers in Trauma Patient OutcomesCompletedNCT03671746Phase 1Results posted
• Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor NephrectomyCompletedNCT03669081Phase 2Results posted
• Photodynamic Therapy-Induced Immune Modulation: Part IIITerminatedNCT03643744Phase 1Results posted

← Cyclooxygenase Inhibitors overview