BiologicalDrug
BTH1677 clinical trials
Also written BTH-1677 and Odetiglucan.
- studies test it
- 15
- open now
- 2
- in phase 3
- 1
- first study started
- 2007
Keep track of what changes. Save the BTH1677 studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Other names
Combined with it in one product
Studies by the year they started
15 studies that test it; most in 2017 (3)
| Year | Studies |
|---|---|
| 2007 | 1 |
| 2009 | 2 |
| 2011 | 2 |
| 2014 | 1 |
| 2017 | 3 |
| 2018 | 1 |
| 2021 | 2 |
| 2022 | 1 |
| 2025 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 6
- Phase 2
- 12
- Phase 3
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 10 · Other 5
HiberCell, Inc. (9) · Lawrence Feldman, MD (1) · Mayo Clinic (1) · Abramson Cancer Center at Penn Medicine (1) · University of Pennsylvania (1) · Hoffmann-La Roche (1) · University of Illinois at Chicago (1)
Often tested with
Tested in the same studies.
Pembrolizumab (5) · Irinotecan (1) · Alemtuzumab (1) · Rituximab (1) · Mitazalimab (1) · CDX-1140 (1) · Regorafenib (1) · Atezolizumab (1)
Studies
Open first, then newest update. How each study uses BTH1677 is read from its arms, and is right about nine times in ten.
Testing it · 15
- Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal AdenocarcinomaRecruitingPhase 2Abramson Cancer Center at Penn MedicineNCT07082439Written as Odetiglucan
- Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic CancerRecruitingPhase 2University of PennsylvaniaNCT07199764Written as Odetiglucan
- Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017CompletedPhase 1/2Lawrence Feldman, MDNCT03003468Written as Imprime PGG
- Safety/Efficacy Study of Imprime PGG With Cetuximab in Patients With Recurrent/Progressive Colorectal CarcinomaCompletedPhase 1/2HiberCell, Inc.NCT00545545Written as Imprime PGG 2 mg/kg
- Study of Imprime PGG and Pembrolizumab in Advanced Melanoma and Triple Negative Breast CancerCompletedPhase 2HiberCell, Inc.NCT02981303Written as Imprime PGG
- A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal AdenocarcinomaTerminatedPhase 1HiberCell, Inc.NCT05484011Written as odetiglucan
- A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)TerminatedPhase 1/2Hoffmann-La RocheNCT03555149Written as Imprime PGG
- Phase 2 Study of Imprime PGG and Pembrolizumab in Patients With HR+/HER2- Metastatic Breast Cancer (mBCA)CompletedPhase 2HiberCell, Inc.NCT05159778Written as Imprime PGG
- Study of Neoadjuvant Imprime PGG and Pembrolizumab for Stage III, Resectable MelanomaWithdrawnPhase 2HiberCell, Inc.NCT04995094Written as Imprime PGG
- Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic LeukemiaCompletedPhase 1/2Mayo ClinicNCT01269385Written as PGG beta-glucan
- Phase 2 Study of Imprime PGG & Pembrolizumab in Subjects With Adv SCCHN Who Failed Pembro Monotherapy or Experiencing SDTerminatedPhase 2HiberCell, Inc.NCT03246685Written as Imprime PGG
- Study of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal CancerTerminatedPhase 3HiberCell, Inc.NCT01309126Written as Imprime PGG + cetuximab
- Efficacy/Safety of Imprime PGG® Injection With Bevacizumab and Paclitaxel/Carboplatin in Patients With Untreated Advanced Non-Small Cell Lung Cancer (NSCLC)CompletedPhase 2HiberCell, Inc.NCT00874107Written as Imprime PGG® Injection
- Efficacy/Safety of Imprime PGG With Cetuximab & Paclitaxel/Carboplatin Therapy in Pts With Untreated Advanced Non-Small Cell Lung CancerCompletedPhase 2HiberCell, Inc.NCT00874848Written as Imprime PGG Injection
- (PM-01) IMPRIME PGG® With BTH1704 and Gemcitabine for Advanced Pancreatic CancerTerminatedPhase 1University of Illinois at ChicagoNCT02132403Written as IMPRIME PGG