Drug
Bivalirudin clinical trials
Also written Angiomax and Angiox.
- studies test it
- 55
- open now
- 5
- in phase 3
- 18
- first study started
- 1999
Keep track of what changes. Save the bivalirudin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
55 studies that test it; most in 2019 (7)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 3 |
| 2005 | 2 |
| 2007 | 2 |
| 2008 | 4 |
| 2009 | 3 |
| 2010 | 3 |
| 2012 | 6 |
| 2013 | 1 |
| 2014 | 2 |
| 2015 | 1 |
| 2016 | 2 |
| 2018 | 3 |
| 2019 | 7 |
| 2020 | 3 |
| 2021 | 2 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 2 |
| 2025 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 5
- Phase 3
- 18
- Phase 4
- 22
- No phase
- 7
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 17 · Other 38
The Medicines Company (14) · Shenyang Northern Hospital (2) · Deutsches Herzzentrum Muenchen (2) · First Affiliated Hospital Xi'an Jiaotong University (2) · The First Affiliated Hospital of Dalian Medical University (2) · NYU Langone Health (1) · Beijing Anzhen Hospital (1) · University of Texas Southwestern Medical Center (1)
Often tested with
Tested in the same studies.
Heparin (10) · Clopidogrel (2) · Prasugrel (2) · Adenosine (1) · Enoxaparin (1) · Ticagrelor (1) · Aspirin (1) · Abciximab (1)
Studies
Open first, then newest update. How each study uses bivalirudin is read from its arms, and is right about nine times in ten.
Testing it · 55
- Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp SystemRecruitingPhase 2Stanford UniversityNCT06080074Written as Bivalirudin
- BivaLirudin versUS Heparin in Extracorporeal Membrane OxygenationRecruitingPhase 2Sydney Local Health DistrictNCT05959252Written as Bivalirudin
- Use of Bivalirudin for Anticoagulation in Patients With Extracorporeal Membrane OxygenationRecruitingNot applicableXiaotong HouNCT06275555Written as bivalirudin
- A Study on the Impact of Bivalirudin Usage During PCI for High-risk Plaques on Post-PCI Coronary Microcirculation.RecruitingPhase 4Peking University First HospitalNCT05984537Written as Bivalirudin
- Bivalirudin with Prolonged Infusion During PCI Versus Heparin After Fibrinolytic TherapyNot yet recruitingNot applicableFirst Affiliated Hospital Xi'an Jiaotong UniversityNCT06861374Written as Bivalirudin
- A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular DysfunctionActive, not recruitingNot applicableNYU Langone HealthNCT03537586Written as Bivalirudin
- Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCICompletedNot applicableShenyang Northern HospitalNCT03822975Written as Bivalirudin
- Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCICompletedPhase 4Beijing Anzhen HospitalNCT03664180Written as Bivalirudin
- Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric ECMOCompletedPhase 4University of Texas Southwestern Medical CenterNCT03318393Written as Bivalirudin
- Bivalirudin Versus Enoxaparin in Critically Ill COVID-19 PatientsCompletedNot applicableUniversity Magna GraeciaNCT05334654Written as Bivalirudin
- Safety and Efficacy of Bivalirudin During Short-term Intervention of Non-infarction Related Artery After PPCI of STEMIStatus unknownNot applicableFirst Affiliated Hospital Xi'an Jiaotong UniversityNCT04475835Written as Bivalirudin
- Reduce Bolus Injection of BivalirudinCompletedPhase 4Han Yaling, MDNCT03588611Written as Bivalirudin
- Bivalirudin vs Heparin in ECMO PatientsWithdrawnPhase 1Johns Hopkins UniversityNCT03707418Written as Bivalirudin Injection [Angiomax]
- Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis Syndrome (HIT/HITTS) PatientsWithdrawnPhase 4The Medicines CompanyNCT00759083Written as bivalirudin
- Efficacy and Safety of Bivalirudin Versus Heparin During Coil Embolization in Patients With Ruptured Intracranial AneurysmsStatus unknownPhase 3Changhai HospitalNCT04532333Written as Bivalirudin 250 MG Injection
- Anticoagulation in Patients Suffering From COVID-19 Disease The ANTI-CO TrialStatus unknownPhase 4Hamad Medical CorporationNCT04445935Written as Bivalirudin Injection
- Multi-center Application of Bivalirudin in Left Atrial Appendage OcclusionStatus unknownPhase 4Shanghai Zhongshan HospitalNCT04195997Written as Bivalirudin
- Bivalirudin in Late PCI for Oatients With STEMIStatus unknownPhase 4Second Xiangya Hospital of Central South UniversityNCT04185077Written as Bivalirudin
- Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.Status unknownPhase 4The First Affiliated Hospital of Dalian Medical UniversityNCT04046029Written as Bivalirudin
- Safety and Efficacy of Bivalirudin Versus Heparin for Systemic Anticoagulation in Extracorporeal Membrane OxygenationStatus unknownPhase 4Legacy Health SystemNCT03965208Written as Bivalirudin
See all 55 studies that test bivalirudin →
Given in every arm · 1 — bivalirudin is usual care beside what is tested
As the comparator · 3 — what is tested is compared with bivalirudin
- Anticoagulant Treatments and Percutaneous Coronary AngioplastyTerminatedPhase 4Centre Hospitalier de PAUNCT00669149Written as bivalirudin + clopidogrel + aspirin
- A Study To Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCITerminatedPhase 3Regado Biosciences, Inc.NCT01848106Written as Bivalirudin
- Randomized Comparison of Abciximab Plus Heparin With Bivalirudin in Acute Coronary SyndromeCompletedPhase 4Deutsches Herzzentrum MuenchenNCT00373451Written as Bivalirudin
Codes
What other systems call bivalirudin · ClinicalTrials.gg INT003633
- MeSH (NLM) C074619bivalirudinConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) TN9BEX005GBIVALIRUDINConfirmed FDA, NLM
- RxNorm 60819One source FDA
- NCI Thesaurus C47415BivalirudinOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C074619 | bivalirudin | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | TN9BEX005G | BIVALIRUDIN | Confirmed FDA, NLM |
| RxNorm | 60819 | — | One source FDA |
| NCI Thesaurus | C47415 | Bivalirudin | One source FDA |
Also registered as bivalirudin trifluoroacetate (UNII 8631NP8608 · RxNorm 2380556).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.