Drug
Avacopan clinical trials
Also written CCX168 and AMG 569.
- studies test it
- 22
- open now
- 6
- in phase 3
- 4
- first study started
- 2009
Keep track of what changes. Save the avacopan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
21 studies that test it; most in 2024 (4); 1 more planned to start later
| Year | Studies |
|---|---|
| 2009 | 1 |
| 2011 | 1 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 1 |
| 2017 | 3 |
| 2018 | 2 |
| 2019 | 1 |
| 2022 | 1 |
| 2024 | 4 |
| 2025 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 10
- Phase 2
- 7
- Phase 3
- 4
- Phase 4
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 16 · Other 6
Amgen (16) · Mayo Clinic (2) · University Hospital, Toulouse (1) · Robert Spiera, MD (1) · Chiba University (1) · Mario Negri Institute for Pharmacological Research (1)
Often tested with
Tested in the same studies.
Prednisolone (2) · Simvastatin (1) · Prednisone (1) · Rituximab (1)
Studies
Open first, then newest update. How each study uses avacopan is read from its arms, and is right about nine times in ten.
Testing it · 22
- Pharmacokinetics Of Emulsified Avacopan Applied By NG TubeRecruitingPhase 1Mayo ClinicNCT07556484Written as Avacopan
- Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)RecruitingPhase 2Mayo ClinicNCT06676579Written as Avacopan
- A Study to Evaluate Avacopan in Participants With ANCA-associated VasculitisRecruitingPhase 4AmgenNCT06072482Written as Avacopan
- TAVNEOS for Otolaryngologic Manifestations of Granulomatosis With PolyangiitisRecruitingPhase 2/3Robert Spiera, MDNCT07176546Written as Avacopan
- Avacopan Added to Standard-of-care Therapy in ANCA-associated Vasculitis With Severe Kidney InvolvementNot yet recruitingPhase 3University Hospital, ToulouseNCT07373262Written as Avacopan
- Avacopan vs Reduced-dose Glucocorticoids in ANCA-associated VasculitisRecruitingPhase 4Chiba UniversityNCT06611696Written as Avacopan, prednisolone and rituximab
- A Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (ESRD)CompletedPhase 1AmgenNCT06468826Written as Avacopan
- Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.Active, not recruitingPhase 3AmgenNCT06321601Written as Avacopan
- A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated VasculitisCompletedPhase 3AmgenNCT02994927Written as Avacopan
- Evaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa (AURORA)CompletedPhase 2AmgenNCT03852472Written as Avacopan
- Controlled Trial Evaluating Avacopan in C3 GlomerulopathyCompletedPhase 2AmgenNCT03301467Written as Avacopan
- Open-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS BlockadeCompletedPhase 2AmgenNCT02384317Written as CCX168
- A Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With ANCA-Associated VasculitisCompletedPhase 2AmgenNCT01363388Written as CCX168
- Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of SimvastatinCompletedPhase 1AmgenNCT06207682Written as Avacopan
- A Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX168 in Healthy ParticipantsCompletedPhase 1AmgenNCT06004960Written as [14C]CCX168
- A Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic ImpairmentCompletedPhase 1AmgenNCT06004934Written as Avacopan
- A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant MedicationsCompletedPhase 1AmgenNCT06004947Written as CCX168
- A Study to Assess the Effect of Avacopan at Therapeutic and Supratherapeutic Doses on the QT/QTc Interval in Healthy ParticipantsCompletedPhase 1AmgenNCT05988034Written as Avacopan
- A Study of CCX168 in Japanese and Caucasian Healthy Adult MalesCompletedPhase 1AmgenNCT05988008Written as CCX168
- A Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168CompletedPhase 1AmgenNCT05988021Written as CCX168
See all 22 studies that test avacopan →
As the comparator · 1 — what is tested is compared with avacopan
Codes
What other systems call avacopan · ClinicalTrials.gg INT000707
- MeSH (NLM) C000620232avacopanConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) O880NM097TAVACOPANConfirmed FDA, NLM, Wikidata
- RxNorm 2572100One source FDA
- Wikidata Q27285470avacopanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C174788AvacopanOne source FDA
- DrugBank DB15011One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000620232 | avacopan | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | O880NM097T | AVACOPAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2572100 | — | One source FDA |
| Wikidata | Q27285470 | avacopan | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C174788 | Avacopan | One source FDA |
| DrugBank | DB15011 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.