Drug
Asparaginase clinical trials
Also written Elspar, Colaspase, Kidrolase and MK-965.
- studies test it
- 45
- open now
- 2
- in phase 3
- 15
- first study started
- 1993
Keep track of what changes. Save the Asparaginase studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Other names
Combined with it in one product
Studies by the year they started
45 studies that test it; most in 2002 (5)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1995 | 1 |
| 1996 | 4 |
| 1997 | 1 |
| 1998 | 3 |
| 1999 | 3 |
| 2000 | 3 |
| 2002 | 5 |
| 2003 | 3 |
| 2005 | 2 |
| 2006 | 1 |
| 2007 | 2 |
| 2008 | 3 |
| 2010 | 1 |
| 2011 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 1 |
| 2019 | 2 |
| 2020 | 2 |
| 2023 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- Phase 2
- 20
- Phase 3
- 15
- Phase 4
- 4
- No phase
- 5
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 44
Children's Oncology Group (9) · St. Jude Children's Research Hospital (7) · National Cancer Institute (NCI) (5) · Dana-Farber Cancer Institute (3) · Goethe University (2) · SWOG Cancer Research Network (2) · The University of Hong Kong (2) · Chang Gung Memorial Hospital (1)
Often tested with
Tested in the same studies.
Dexamethasone (28) · Methotrexate (25) · Vincristine (24) · Mercaptopurine (23) · Cytarabine (22) · Cyclophosphamide (22) · Daunorubicin (20) · Etoposide (20)
Studies
Open first, then newest update. How each study uses Asparaginase is read from its arms, and is right about nine times in ten.
Testing it · 45
- Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in ChildrenRecruitingPhase 2Hee Young JuNCT06099366Written as induction: vincristine, L-asparaginase, dexamethasone, intrathecal Ara-C, intrathecal Methotrexate
- Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous LineageRecruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT04440267Written as L-Asparaginase
- Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down SyndromeActive, not recruitingPhase 3Children's Oncology GroupNCT02521493Written as Asparaginase
- Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedPhase 3National Cancer Institute (NCI)NCT01371981Written as Asparaginase
- PK, PD, Safety and Immunogenicity of Spectrila in Adults With Acute B-cell Lymphoblastic LeukaemiaTerminatedPhase 2medac GmbHNCT03156790Written as Spectrila®
- A Study in Adults With Untreated Acute Lymphoblastic LeukemiaCompletedPhase 2Dana-Farber Cancer InstituteNCT00136435Written as asparaginase
- ALL Adult Consortium Trial: Adult ALL TrialCompletedPhase 2Dana-Farber Cancer InstituteNCT00476190Written as E. coli Asparaginase
- Compassionate Use of Asparaginase and Pembrolizumab Combination Theaapy for Nasopharyngeal CarcinomaCompletedNot applicableChang Gung Memorial HospitalNCT06676293Written as asparaginase
- German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 4Goethe UniversityNCT00198978Written as Asparaginase
- German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)CompletedPhase 4Goethe UniversityNCT00198991Written as Asparaginase
- Asparaginase Activity Monitoring (AAM) in Adult Patients With Acute Lymphoblastic Leukemia (ALL)TerminatedPhase 2Gruppo Italiano Malattie EMatologiche dell'AdultoNCT03668392Written as Asparaginase
- Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedPhase 3Children's Oncology GroupNCT00369317Written as asparaginase
- Nivolumab in Combination With GDP/ L-asparaginase in NK/ T-cell LymphomaWithdrawnPhase 1National Cancer Centre, SingaporeNCT04230330Written as IV L-asparaginase
- VP-16, Ifosfamide, Dexamethasone, L-asparaginase Chemotherapy in Patients With Extranodal Natural Killer T Cell Lymphoma (VIDL+ASCT)Status unknownPhase 2Samsung Medical CenterNCT02544425Written as L-asparaginase
- Therapy for Newly Diagnosed Patients With Acute Lymphoblastic LeukemiaCompletedPhase 3St. Jude Children's Research HospitalNCT00137111Written as Doxorubicin, L-asparaginase, PEG-L-asparaginase, Erwinia asparaginase
- Pethema LAL-RI/2008: Treatment for Patients With Standard Risk Acute Lymphoblastic LeukemiaCompletedPhase 4PETHEMA FoundationNCT02036489Written as L-asparaginase
- Erwinia Asparaginase After Allergy to PEG-Asparaginase in Treating Young Patients With Acute Lymphoblastic LeukemiaCompletedNot applicableChildren's Oncology GroupNCT00537030Written as Asparaginase
- Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride With Asparaginase in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaWithdrawnPhase 2University of WashingtonNCT02538926Written as Asparaginase
- SIMPLE Chemotherapy for NK Lymphoma/LeukaemiaStatus unknownPhase 3The University of Hong KongNCT03623087Written as L-asparaginase
- Combination Chemotherapy Including Cisplatin, Ifosfamide, Gemcitabine, L-asparaginase, Etoposide and Dexamethasone as Treatment of Newly Diagnosed and Relapsed/Refractory Peripheral T Cell LymphomasStatus unknownPhase 4The University of Hong KongNCT03071822Written as L-asparaginase
See all 45 studies that test Asparaginase →
Given in every arm · 26 — Asparaginase is usual care beside what is tested
- Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic LeukemiaRecruitingPhase 3Alliance for Clinical Trials in OncologyNCT03150693Written as Pegylated L-Asparaginase
- Ma-Spore ALL 2020 StudyRecruitingPhase 2National University Hospital, SingaporeNCT06336395Written as L-Asparaginase
- PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic LymphomaActive, not recruitingPhase 1/2Therapeutic Advances in Childhood Leukemia ConsortiumNCT03817320Written as Asparaginase
- Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00557193Written as Asparaginase
- Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00381680Written as asparaginase
- Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First RemissionCompletedPhase 3Eastern Cooperative Oncology GroupNCT00002514Written as asparaginase
- Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic LeukemiaCompletedPhase 1/2National Cancer Institute (NCI)NCT00061945Written as asparaginase
- Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedPhase 3Children's Oncology GroupNCT00372593Written as asparaginase
- Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 2/3National Cancer Institute (NCI)NCT00720109Written as Asparaginase
- Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic LymphomaCompletedPhase 3Children's Oncology GroupNCT00004228Written as asparaginase
- Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)CompletedPhase 1/2Children's Oncology GroupNCT00098839Written as L-asparaginase
- Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedPhase 3Children's Oncology GroupNCT00002744Written as asparaginase
- Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaCompletedPhase 2National Cancer Institute (NCI)NCT00873093Written as L-asparaginase
- Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 StudyStatus unknownPhase 4National University Hospital, SingaporeNCT02894645Written as L-Asparaginase
- Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic LeukemiaCompletedPhase 2Alliance for Clinical Trials in OncologyNCT00003700Written as asparaginase
- Combination Chemotherapy Followed by Melphalan and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Acute Myeloid LeukemiaCompletedPhase 1Children's Oncology GroupNCT00004056Written as asparaginase
- CINJALL: Treatment for Children With Acute Lymphocytic LeukemiaCompletedPhase 2Rutgers, The State University of New JerseyNCT00176462Written as L-asparaginase
- Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic LeukemiaCompletedPhase 4Ruijin HospitalNCT01358253Written as L-asparaginase
- Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic LeukemiaCompletedPhase 3National Cancer Institute (NCI)NCT00022737Written as asparaginase
- Combination Chemotherapy and Imatinib Mesylate in Treating Children With Relapsed Acute Lymphoblastic LeukemiaCompletedNot applicableNational Cancer Institute (NCI)NCT00049569Written as asparaginase
Showing 20 of 26.
As the comparator · 7 — what is tested is compared with Asparaginase
- Comparing the Efficacy of VHAG and Traditional Chemotherapy Regimens in Newly Diagnosed ETP-ALLRecruitingPhase 3First Affiliated Hospital of Zhejiang UniversityNCT06361329Written as L-ASP
- Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic LeukemiaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT02101853Written as Asparaginase
- 05-001: Treatment of Acute Lymphoblastic Leukemia in ChildrenCompletedPhase 3Dana-Farber Cancer InstituteNCT00400946Written as asparaginase
- Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic LymphomaCompletedPhase 3National Cancer Institute (NCI)NCT00408005Written as Asparaginase
- GRASPA (Erythrocytes Encapsulating L-asparaginase) in Patients With Relapse of Acute Lymphoblastic LeukemiaCompletedPhase 2/3ERYtech PharmaNCT01518517Written as L-asparaginase
- Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008Status unknownNot applicableFederal Research Institute of Pediatric Hematology, Oncology and ImmunologyNCT01953770Written as E.coli L-asparaginase
- Comparative Efficacy and Safety of Two Asparaginase Preparations in Children With Previously Untreated Acute Lymphoblastic LeukaemiaCompletedPhase 3medac GmbHNCT00784017Written as asparaginase
Codes
What other systems call Asparaginase · ClinicalTrials.gg INT007027
- MeSH (NLM) D001215AsparaginaseOne source ClinicalTrials.gov
- UNII (FDA) G4FQ3CKY5RASPARAGINASEConfirmed FDA, Wikidata
- RxNorm 1156Confirmed FDA, Wikidata
- NCI Thesaurus C286AsparaginaseOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D001215 | Asparaginase | One source ClinicalTrials.gov |
| UNII (FDA) | G4FQ3CKY5R | ASPARAGINASE | Confirmed FDA, Wikidata |
| RxNorm | 1156 | — | Confirmed FDA, Wikidata |
| NCI Thesaurus | C286 | Asparaginase | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.