Ascorbic Acid: all 408 studies that test it

Page 2 of 5. Open to participants first (60), then studies with results posted, then the rest; newest registration first within each.

• A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and EffectiveCompletedNCT01754987Phase 1/2Results posted
• Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung FunctionCompletedNCT01723696Phase 2/3Results posted
• Safety & Efficacy Study of Gemcitabine...With High Dose IV Vit. C (HDIVC)TerminatedNCT01654861Phase 1Results posted
• High Dose Vitamin C in the Critically Ill PatientTerminatedNCT01587963Phase 2Results posted
• Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic CaTerminatedNCT01555489Phase 2Results posted
• Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CATerminatedNCT01550510Phase 1/2Results posted
• Ascorbic Acid (Vitamin C) Infusion in Human SepsisCompletedNCT01434121Phase 1/2Results posted
• The Effect of High Dose Vitamin C on the Liver Function in Chronic Hepatitis PatientsCompletedNCT01413360Phase 4Results posted
• Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01398943Not applicableResults posted
• The Relationship of Hemoglobin A1c and Diabetic Wound HealingTerminatedNCT01350102Phase 4Results posted
• A Comparison of Solid and Soluble Forms of Cold and Influenza RemediesCompletedNCT01332578Phase 4Results posted
• Study of High Dose Vitamin C On Outcome in Cardiac Surgery PatientsCompletedNCT01167569Phase 4Results posted
• Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery ProceduresCompletedNCT01107730Phase 3Results posted
• Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac SurgeryCompletedNCT00953212Phase 3Results posted
• Respiratory and Autonomic Plasticity Following Intermittent HypoxiaCompletedNCT00860743Early Phase 1Results posted
• Quantitative in Vivo Biomarkers of Oxidative Stress in DiabetesCompletedNCT00845130Not applicableResults posted
• Influence of Endothelial Function on Central and Peripheral Causes Of Exercise Impairment in Type 2 DiabetesCompletedNCT00786019Not applicableResults posted
• Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma PatientsCompletedNCT00661544Phase 1/2Results posted
• Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL)TerminatedNCT00626444Phase 2Results posted
• Cephalon Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic SyndromeCompletedNCT00621023Phase 2Results posted
• A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial DysfunctionCompletedNCT00532844Phase 2Results posted
• Clinical Utility of Endothelial Dysfunction in PADTerminatedNCT00491751Phase 1Results posted
• Trial of Arsenic Trioxide With Ascorbic Acid in the Treatment of Adult Non-Acute Promyelocytic Leukemia (APL) Acute Myelogenous LeukemiaTerminatedNCT00184054Phase 2Results posted
• Comparison of Fractional CO2 Laser Monotherapy and Its Combination With Either Topical Vitamin C or Topical Timolol in the Treatment of Post-Acne Erythema: A Split Face StudyCompletedNCT07884565Phase 2
• Thiamine, Ascorbic Acid, and Their Combination on MMP-9/TIMP-1 and Inflammatory Balance in SepsisCompletedNCT07786350Not applicable
• Cerebral Hemodynamic Effects of Oxygen and Antioxidants (CHEOXANT)CompletedNCT07369232Not applicable
• Effect of Double Nutri® Liposomal Encapsulation Technology on Human Absorption of Vitamin C and Glutathione Liquid SachetCompletedNCT07302828Not applicable
• Effects of Dietary Nitrate and Vitamin C Co-supplementation on Blood Pressure and Endothelial Function in Overweight IndividualsCompletedNCT07242066Not applicable
• Oxidative DNA Damage Enhancement by Vitamin C Among Narghile Smokers and Non-smokersCompletedNCT07141823Not applicable
• The Effects of Vitamin C on Acute-Exercise in Postmenopausal FemalesTerminatedNCT07109115Not applicable
• Efficacy of Vitamin C Supplementation on Malondialdehid Levels and Disease Activity in SLE PatientsCompletedNCT07083622Not applicable
• Oral Vitamin C Administration on Erythropoietin Dosing Requirement in End-Stage Renal Disease Patients on Regular HemodialysisCompletedNCT07076108Not applicable
• Efficacy of Vitamin C Supplementation on Serum TNF-α Levels and Disease Activity in SLE PatientsCompletedNCT07071233Not applicable
• Efficacy of Vitamin C Supplementation on Serum IL-6 Levels and Disease Activity in Systemic Lupus Erythematosus PatientsCompletedNCT07071220Not applicable
• Does Vitamin C Improve Postoperative HealingCompletedNCT07012564Not applicable
• Impact of Vitamin C on Pain Detection and Tolerance ThresholdCompletedNCT06971315Not applicable
• High-dose Intravenous Vitamin C for the Treatment of Severe Acute PancreatitisActive, not recruitingNCT06897384Not applicable
• The Effect of Nutritional Supplementation on Actinic Purpura: A Pilot StudySuspendedNCT06840574Not applicable
• Role of Vitamin C Infusion in Postoperative Mechanically Ventilated Neonates With SepsisCompletedNCT06780345Not applicable
• Effects of Vitamin C on Shock Duration and Microcirculation in Patients With Vasoplegia Syndrome After Cardiac SurgeryCompletedNCT06723626Not applicable
• Comparison Between IPRF With Vit. C and IPRF Alone in Management of ID'PainCompletedNCT06345092Not applicable
• Vitamin C Deficiency in Septic ShockCompletedNCT06224881Phase 4
• Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock.CompletedNCT06152458Phase 4
• The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) PatientsActive, not recruitingNCT06074367Phase 4
• Vitamin C to Chemotherapy Related Anemia in Pancreatic CancerActive, not recruitingNCT06018883Phase 3
• The Effect of Vitamin C for Iron Supplementation During Pregnancy with Risk of AnemiaCompletedNCT05975125Not applicable
• A Study to Compare Liposomal Iron With Ferrous Ascorbate in the Treatment of Iron Deficiency Anemia in ChildrenStatus unknownNCT05957328Phase 3
• Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung CancerTerminatedNCT05849129Phase 2
• Comparison of Bioavailability of Liposomal and Traditional Formulation of Vitamin CCompletedNCT05843617Not applicable
• Vitamin c Supplementation in the Prevention of CRPS Following Distal Radius FracturesCompletedNCT05842395Phase 4
• Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival PhenotypeStatus unknownNCT05841303Phase 4
• An Investigator-initiated Trial to Assess the Effectiveness of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy ChildrenCompletedNCT05775237Not applicable
• Vitamin C on Acute and Chronic Post Mastectomy PainCompletedNCT05770596Not applicable
• Ascorbic Acid to Prevent Postreperfusion Syndrome in Liver TransplantationStatus unknownNCT05754242Phase 2
• Broccoli Seed Extract and Skin HealthCompletedNCT05745636Not applicable
• UVB-Induced MVP Release in Human SkinCompletedNCT05734235Phase 1
• Bowel Preparation Regimen for Colon Capsule Endoscopy ProcedureCompletedNCT05726097Phase 3
• Efficacy, Tolerability and Safety of Intravenous D-VC With ATO in Patients With Advanced/Metastatic Colorectal CancerStatus unknownNCT05721872Phase 1/2
• Efficacy of Megadose Vitamin C in Severe and Critical Ill COVID-19 Patients.Status unknownNCT05694975Phase 2/3
• Effect of Colon Delivered Vitamin C on Gut Microbiota and Related Health Biomarkers in Healthy Older AdultsCompletedNCT05598619Not applicable
• Vitamin C as add-on Therapy in Patients With Acute Herpes ZosterTerminatedNCT05561257Phase 2
• Evaluation of the Effect of Citicoline and Docosahexaenoic Acid (DHA) on the Visual Function of Patients With GlaucomaCompletedNCT05527106Not applicable
• The Impact of Intravenous Vitamin C Combined With Nerve Blocks on Postoperative Pain and Recovery After Total Knee ArthroplastyCompletedNCT05514197Not applicable
• Effect of Ascorbic Acid Final Flush on Post-operative Pain in Mandibular Molars.Status unknownNCT05478044Not applicable
• Treatment of Non-Anemic Iron Deficiency in PregnancyCompletedNCT05423249Not applicable
• The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on HaemodialysisStatus unknownNCT05350124Phase 3
• Effectiveness of Vitamin C Supplementation in Treatment of RicketsCompletedNCT05310760Phase 2/3
• Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of LifeCompletedNCT05242562Not applicable
• Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.CompletedNCT05215743Phase 1
• Clinical Efficacy of Megadose Vitamin C in SepsisCompletedNCT05194189Phase 2
• Vitamin C, Hydrocortisone and Thiamine in Patients With Septic ShockTerminatedNCT05192213Phase 3
• Antioxidants Vitamins and Muscle DamageCompletedNCT05127928Not applicable
• Vitamin C 4 Care HomesWithdrawnNCT05122481Not applicable
• The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With PeriodontitisStatus unknownNCT05009355Early Phase 1
• Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in AfricaStatus unknownNCT04999137Phase 2
• Hmong Microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C)CompletedNCT04938024Not applicable
• Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest SurvivorsCompletedNCT04921189Phase 2
• High Doses Vitamin C and Tissular Repair in Surgical PatientsCompletedNCT04896359Not applicable
• Gemcitabine With Ascorbate Including AdolescentsWithdrawnNCT04877587Early Phase 1
• Antioxidant Vitaminas and Hypertrophy Adaptations to Resistance TrainingCompletedNCT04828642Not applicable
• Vitamin D, Omega-3, and Combination Vitamins B, C and Zinc Supplementation for the Treatment and Prevention of COVID-19WithdrawnNCT04828538Not applicable
• Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal CancerStatus unknownNCT04801511Phase 2
• High-dose Intravenous Vitamin C in Patients With Septic ShockStatus unknownNCT04796636Phase 1
• The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional InterventionCompletedNCT04783792Not applicable
• The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In SepsisCompletedNCT04773717Not applicable
• FLIO and the Influence of Oral Lutein Supplementation on Macular PigmentCompletedNCT04761341Phase 4
• Parenteral Ascorbic Acid Repletion in TransplantatIonWithdrawnNCT04756063Phase 4
• Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative StudyCompletedNCT04697992Not applicable
• Role of Mega Dose of Vitamin C in Critical COVID-19 PatientsCompletedNCT04682574Not applicable
• Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)Active, not recruitingNCT04634227Early Phase 1
• Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon CleansingCompletedNCT04598880Phase 4
• Impact of Vitamin C on Biomarkers of Neurologic Injury in Survivors of Cardiac ArrestStatus unknownNCT04563000Phase 2
• RCT,Double Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMUStatus unknownNCT04558424Not applicable
• The Effect of Melatonin and Vitamin C on COVID-19CompletedNCT04530539Not applicable
• Perioperative Vitamin C Lung TransplantWithdrawnNCT04505878Phase 2
• Efficacy of Vitamin C on AKI Outcomes in Critically Ill Cirrhotics With Multidrug-resistant Bacterial Infections.CompletedNCT04494451Not applicable
• Potentiation of Chemotherapy in Brain Tumors by ZincStatus unknownNCT04488783Not applicable
• 16 Weeks' Dietary Supplementation With Iron and Iron + Vitamin C on Cerebral Blood Flow and Energy Expenditure in Women of Reproductive AgeCompletedNCT04477018Not applicable
• Can Vitamin C Reduce the Risk of Postoperative Shoulder Stiffness?TerminatedNCT04472000Phase 4
• Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-beingCompletedNCT04469010Not applicable

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