An interventional study of Cyruta Plus: A Whole-Food Based Vitamin C supplement containing organic buckwheat (aerial parts) juice powder, organic buckwheat flour, bovine adrenal Cytosol™ extract, oat flour, honey, ascorbic acid and Low Dose Vitamin C in Skin Health, Skin Aging of Face and Hands and Healthy, sponsored by Standard Process Inc.. Suspended at 1 site in United States. Open to participants aged 55 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-02-23.
Sponsored by Standard Process Inc. · Not applicable, Interventional, and Other
Purpura is a macule or papule of blood in the skin. It is mostly seen in mature skin that is often prone to significant bruising. Small lesions of less than 5 mm are called petechiae and larger ones, found mostly in subcutaneous tissue, are called ecchymosis. Actinic purpura occurs almost exclusively in elderly populations. This single-blind randomized clinical trial evaluates the effect of an 8-week nutritional supplement intervention in comparison with isolated vitamin C supplements on actinic purpura in older adults. We will enroll thirty (30) otherwise healthy participants, both male and female, aged 55 years and older. Changes in participants' skin condition will be assessed at visit 1 (baseline), visit 2 (4-week), and visit 3 (8-week) using questionnaires, standard digital photography, and clinical grading of the skin lesions.
38 studies on the registry are indexed under Ecchymosis; 6 are open to participants now.
This study's planned enrollment of 30 is below the median of 66 across 34 interventional studies indexed under Ecchymosis.
Browse Ecchymosis studies →Standard Process Inc. is the lead sponsor of 11 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
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The human immunodeficiency virus, which weakens the immune system.
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Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Clinically significant
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Total of 27 mg daily
Dietary Supplement: Cyruta Plus: A Whole-Food Based Vitamin C supplement containing organic buckwheat (aerial parts) juice powder, organic buckwheat flour, bovine adrenal Cytosol™ extract, oat flour, honey, ascorbic acid
Total of 27 mg daily
Dietary Supplement: Low Dose Vitamin C
Total of 500 mg daily
Dietary Supplement: High Dose Vitamin C
27 mg vitamin C, organic buckwheat (aerial parts) juice powder, organic buckwheat flour, bovine adrenal Cytosol™ extract, oat flour, honey, ascorbic acid, and calcium stearate
27 mg ascorbic acid
500 mg ascorbic acid
Primary Endpoint
The number of participants who report a reduction in the number of purpura lesions as evaluated through dermatological examination before and after supplementation.
Time frame: 8 weeks
Secondary Endpoint
Average decrease in actinic purpura lesion measurements in millimeters across participants.
Time frame: 8 weeks
Plan to share: No
No publications or documents are linked to this record.
Started Apr 2025 (actual). Primary completion is estimated for Apr 2026, 12 months after the start.
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This study is suspended, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Ascorbic Acid
Standard Process Inc.