An interventional study of Citicoline and Docosahexaenoic Acid (DHA) in Glaucoma, sponsored by Institut Catala de Retina. Completed at 1 site in Spain. Open to participants aged 50 Years to 75 Years. Per ClinicalTrials.gov, last updated 2022-09-02.
Sponsored by Institut Catala de Retina · Not applicable, Interventional, and Supportive care
Pilot, single-blind, randomized and controlled study to evaluate the changes produced in the visual function of patients with glaucoma after oral administration for 3 months of citicoline and docosahexaenoic Acid (DHA) vs citicoline and docosahexaenoic Acid (DHA) vs vitamin C.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 73 is above the median of 65 across 1,272 interventional studies indexed under Glaucoma.
Browse Glaucoma studies →Institut Catala de Retina is the lead sponsor of 3 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with chronic, primary or secondary, open or closed angle glaucoma, diagnosed by meeting the following criteria:
Glaucoma with functional and structural damage.
Exclusion Criteria:
Cebrolux 800 is a food supplement based on citicoline (163 mg) that also contains vitamin A, E, C and B6.
Dietary Supplement: Citicoline
Brudypio 1.5g is a food supplement based on Omega-3 fatty acid in the form of triglycerides (DHA 70% \[350 mg\], EPA 8.5%, DPA 6%) that also contains vitamins (A, B1, B2, B3, B6, B9, B12, C, E), carotenoids ( lutein, zeaxanthin, lycopene), glutathione, coenzyme Q10 and minerals (Zn, Se, Cu, Mn).
Dietary Supplement: Docosahexaenoic Acid (DHA)
Cebrolux 800 and Brudypio 1.5g (see above).
Dietary Supplement: Citicoline and Docosahexaenoic Acid (DHA)
Vitamin C.
Dietary Supplement: Vitamin C
Every subject randomized into this group have to take 2 sachets of Cebrolux 800 (362 mg of citicoline per day), every day, for 3 months.
Also known as: Cebrolux 800
Every subject randomized into this group have to take 3 pills of Brudypio 1.5g (1050 mg of DHA per day), every day, for 3 months.
Also known as: Brudypio 1.5g
Every subject randomized into this group have to take 2 sachets of Cebrolux 800 and 3 pills of Brudypio 1.5g per day, every day, for 3 months.
Every subject randomized into this group have to take 1 pills of Vitamin C (500 mg per day), every day, for 3 months.
Also known as: L-ascorbic acid
Effect on Mean Defect (MD)
Evaluation of changes on the MD (decibels) with study treatment.
Time frame: From Baseline to Month 3.
Effect on Visual Field Index (VFI)
Evaluation of changes on the VFI (%) with study treatment.
Time frame: From Baseline to Month 3.
Evaluation of the changes produced in the intraocular pressure (IOP)
To compare IOP (mmHg) measurements with study treatment.
Time frame: From Baseline to Month 3.
Evaluation of tolerance
Describe the tolerance and the adverse events with study treatment.
Time frame: From Month 1 to Month 3
This study is completed, as verified in Sep 2022. You cannot join it, but the record below documents what was studied.
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