Antimetabolites: all 8,294 studies that test it

Page 17 of 83. Open to participants first (1,149), then studies with results posted, then the rest; newest registration first within each.

• Pacritinib Combined With Decitabine or Cytarabine in Older Patients With AMLTerminatedNCT02532010Phase 2Results posted
• Albumin-Bound Paclitaxel and Gemcitabine in Patients With Untreated Stage IV or Recurrent Squamous Cell Lung CancersCompletedNCT02525653Phase 2Results posted
• Docetaxel and Capecitabine With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and NeckTerminatedNCT02524275Phase 2Results posted
• Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)CompletedNCT02522104Phase 4Results posted
• Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down SyndromeActive, not recruitingNCT02521493Phase 3Results posted
• ABT-450/Ritonavir/ ABT-267 (ABT-450/r/ABT-267) and ABT-333 Co-Administered With Ribavirin (RBV) in Treatment Naïve and Treatment Experienced Asian Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Compensated CirrhosisCompletedNCT02517528Phase 3Results posted
• A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLLActive, not recruitingNCT02514083Phase 2Results posted
• 8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT02509546Phase 1/2Results posted
• Leflunomide in Treating Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT02509052Phase 1/2Results posted
• Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple MyelomaCompletedNCT02506959Phase 2Results posted
• Effects of Abatacept in Patients With Early Rheumatoid ArthritisCompletedNCT02504268Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/r With or Without Dasabuvir and With or Without Ribavirin in Chronic Hepatitis C Virus Genotype 1 or 4 Infected Adults With Successfully Treated Early Stage Hepatocellular CarcinomaTerminatedNCT02504099Phase 3Results posted
• Study of TAS-102 or Placebo Plus BSC in Patients With Metastatic Gastric CancerCompletedNCT02500043Phase 3Results posted
• Phase 2a RDEA3170 and Allopurinol Combination Study in Gout SubjectsCompletedNCT02498652Phase 2Results posted
• Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CRCompletedNCT02497404Phase 2Results posted
• A Phase Ib, Open-label, Multicenter Study of the Safety and PK of the Combination of rhuMAb2c4 (Omnitarg), a Recombinant Humanized Antibody to HER2, and Capecitabine (Xeloda) in Patients With Advanced Solid TumorsCompletedNCT02494596Phase 1Results posted
• A Study to Evaluate Long-term Safety of CC-486 (Oral Azacitidine) in Subjects With Hematological DisordersCompletedNCT02494258Phase 2Results posted
• Ombitasvir/ABT-450/Ritonavir and Dasabuvir Therapy With Low Dose Ribavirin (RBV), Full Dose RBV or RBV Add-On in Treatment Naive Genotype 1a Hepatitis C Virus Infected AdultsCompletedNCT02493855Phase 2Results posted
• A Phase Ib/II Multicenter Open-label Study of Bemcentinib (BGB324) in Patients With AML or MDSCompletedNCT02488408Phase 1/2Results posted
• Prospective Study of Patients With Thrombocytopenia Following HSCTCompletedNCT02487563Phase 3Results posted
• Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination, With or Without Ribavirin, in Egyptian Adults With Chronic Genotype 4 HCV InfectionCompletedNCT02487030Phase 3Results posted
• A Study to Evaluate Treatment of Hepatitis C Virus Infection in Pediatric SubjectsCompletedNCT02486406Phase 2/3Results posted
• Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AMLTerminatedNCT02485353Not applicableResults posted
• CPI-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic SarcomaCompletedNCT02484391Phase 1Results posted
• An Investigational Immuno-therapy Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum-doublet Chemotherapy, Compared to Platinum Doublet Chemotherapy in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)CompletedNCT02477826Phase 3Results posted
• Ombitasvir/ABT-450 (Paritaprevir)/Ritonavir With Dasabuvir and Ribavirin (RBV) in Treatment Naive and Treatment Experienced Genotype 1a Hepatitis C Virus Infected AdultsCompletedNCT02476617Phase 3Results posted
• Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV InfectionCompletedNCT02472886Phase 3Results posted
• Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)CompletedNCT02464657Phase 1/2Results posted
• Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell TransplantationCompletedNCT02458235Phase 2Results posted
• Reversal of Hepatic Impairment in Patients With Hepatitis C Virus (HCV) and Early Decompensation of CirrhosisTerminatedNCT02455167Phase 3Results posted
• IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIACompletedNCT02451748Phase 4Results posted
• A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ABT-493 and ABT-530 With and Without Ribavirin in Adults With HCV Who Failed a Prior DAA Containing TherapyCompletedNCT02446717Phase 2/3Results posted
• A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in US Veterans With Genotype 1 Chronic Hepatitis C Virus InfectionCompletedNCT02442284Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of Three Experimental Drugs in Adults With Hepatitis C Virus Infection, Who Are Either Treatment-naive or Treatment-experienced in BrazilCompletedNCT02442271Phase 3Results posted
• AML-02: Omacetaxine With Standard-of-Care Induction With Cytarabine & Idarubicin in Newly-Diagnosed AML PatientsTerminatedNCT02440568Phase 1/2Results posted
• Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger PatientsTerminatedNCT02433483Phase 2Results posted
• Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by SurgeryCompletedNCT02427841Phase 2Results posted
• Pemetrexed Disodium in Treating Patients With Stage IV Non-small Cell Lung Cancer and ECOG Performance Status 3CompletedNCT02426658Phase 2Results posted
• Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related DisordersActive, not recruitingNCT02425904Phase 2Results posted
• MK-3475 and Gemcitabine in Non-Small Cell Lung Cancer (NSCLC)Active, not recruitingNCT02422381Phase 1/2Results posted
• Evaluate if Response to Infliximab or Adalimumab May be Regained With an ImmunomodulatorTerminatedNCT02413047Not applicableResults posted
• Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract CancerCompletedNCT02412670Phase 2Results posted
• Lirilumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid LeukemiaTerminatedNCT02399917Phase 2Results posted
• Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Co-Administered With Sofosbuvir With and Without Ribavirin in Treatment-Naive HCV Genotype 1-Infected AdultsCompletedNCT02399345Phase 3Results posted
• Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRCCompletedNCT02394795Phase 3Results posted
• Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal CancerCompletedNCT02393755Phase 1/2Results posted
• Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary CancersCompletedNCT02392637Phase 2Results posted
• FLT PET/CT in Measuring Response in Patients With Previously Untreated Acute Myeloid LeukemiaActive, not recruitingNCT02392429Phase 2Results posted
• Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal Cancer Receiving Combination ChemotherapyTerminatedNCT02392377Phase 2Results posted
• Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) PainTerminatedNCT02385266Phase 4Results posted
• Regorafenib Plus Gemcitabine in Metastatic Pancreatic CancerTerminatedNCT02383433Phase 2Results posted
• Etanercept and Methotrexate in Combination or as Monotherapy in Psoriatic ArthritisCompletedNCT02376790Phase 3Results posted
• Improving Therapeutic Learning in Depression: Proof of ConceptCompletedNCT02376257Phase 2Results posted
• Study to Assess the Efficacy and Safety of the Epigenetic Modifying Effects of CC-486 (Oral Azacitidine) in Combination With FulvestrantTerminatedNCT02374099Phase 2Results posted
• Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis RemissionCompletedNCT02373813Phase 3Results posted
• A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML PatientsCompletedNCT02367456Phase 1Results posted
• Inflammation and Coronary Endothelial FunctionCompletedNCT02366091Phase 2Results posted
• Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and StomachTerminatedNCT02358863Not applicableResults posted
• Efficacy and Safety of Combination Grazoprevir (MK-5172)/Elbasvir (MK-8742) Versus Sofosbuvir + Pegylated Interferon + Ribavirin in Hepatitis C Virus Genotype 1, 4 or 6 Infection (MK-5172-077)CompletedNCT02358044Phase 3Results posted
• A Study of Pembrolizumab (MK-3475) for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck (MK-3475-048/KEYNOTE-048)CompletedNCT02358031Phase 3Results posted
• A Study of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Sofosbuvir and Ribavirin in Direct-Acting Antiviral Agent Treatment-Experienced Adults With Chronic Hepatitis C Virus InfectionCompletedNCT02356562Phase 2Results posted
• Tosedostat With Capecitabine in Patients With Metastatic Pancreatic AdenocarcinomaTerminatedNCT02352831Phase 1/2Results posted
• First-line Metastatic Pancreatic Cancer : FOLFIRINOX +/- LV5FU2 in Maintenance Versus FirgemCompletedNCT02352337Phase 2Results posted
• Study of Ibrutinib in Subjects With Acute Myeloid LeukemiaTerminatedNCT02351037Phase 2Results posted
• Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCTTerminatedNCT02349178Phase 2Results posted
• Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin LymphomaCompletedNCT02348216Phase 1/2Results posted
• A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural MesotheliomaCompletedNCT02347917Phase 1/2Results posted
• Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II StudyTerminatedNCT02345460Phase 2Results posted
• Deferasirox, Cholecalciferol, and Azacitidine in the Treatment of Newly Diagnosed AML Patients Over 65TerminatedNCT02341495Phase 2Results posted
• Evaluate the Efficacy and Safety of TG-2349 in Subjects With Hepatitis C InfectionCompletedNCT02340962Phase 2Results posted
• Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal CarcinomaCompletedNCT02337946Phase 2Results posted
• Treatment of Hemoglobin SC Disease With HydroxyureaTerminatedNCT02336373Phase 2Results posted
• Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Virus (HCV) Genotype (GT) 3, GT4, GT5, and GT6 Infection (MK-3682-012)CompletedNCT02332720Phase 2Results posted
• New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System InvolvementCompletedNCT02329080Phase 2Results posted
• Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid LeukemiaCompletedNCT02328755Phase 1/2Results posted
• Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic CancerCompletedNCT02324543Phase 1/2Results posted
• Phase III Study of TAS-118 Plus Oxaliplatin Versus S-1 Plus Cisplatin in Patients With Advanced Gastric CancerCompletedNCT02322593Phase 3Results posted
• Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS)TerminatedNCT02319369Phase 1Results posted
• Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal AdenocarcinomaTerminatedNCT02319304Phase 2Results posted
• Safety and Efficacy Study of the Combination Daclatasvir (60 mg), Sofosbuvir (400 mg) and Ribavirin (Weight-based Dosing) for 12 or 16 Weeks in Subjects With Genotype 3 Chronic HCV Infection With or Without Prior Treatment Experience and Advanced Fibrosis or Compensated CirrhosisCompletedNCT02319031Phase 3Results posted
• Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube CancerCompletedNCT02312245Phase 2Results posted
• Ribavirin for Patients With Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related MalignanciesCompletedNCT02308241Not applicableResults posted
• An Investigational Immuno-therapy Study of Ulocuplumab in Combination With Low Dose Cytarabine in Patients With Newly Diagnosed Acute Myeloid LeukemiaTerminatedNCT02305563Phase 1/2Results posted
• Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserineCompletedNCT02304432Early Phase 1Results posted
• Study to Evaluate the Safety and Efficacy of Daclatasvir/Sofosbuvir/Ribavirin for 16 Versus 24 Weeks for HCV Genotype 3 CirrhoticsCompletedNCT02304159Phase 4Results posted
• SARC018: A Study of Mocetinostat and Gemcitabine in Patients With Metastatic LeiomyosarcomaCompletedNCT02303262Phase 2Results posted
• Phase 2 Nab® -Paclitaxel (Abraxane®) Plus Gemcitabine in Subjects With Locally Advanced Pancreatic Cancer (LAPC)CompletedNCT02301143Phase 2Results posted
• Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder CancerCompletedNCT02300610Phase 1Results posted
• Locally Advanced Breast Cancer: Individualized Treatment Based On Tumor Molecular CharacteristicsTerminatedNCT02297230Phase 1/2Results posted
• A Study Assessing the Efficacy and Safety of Sarilumab Added to MTX in Japanese Patients With Moderately to Severely Active Rheumatoid Arthritis (SARIL-RA-KAKEHASI)CompletedNCT02293902Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir With Sofosbuvir With or Without Ribavirin in Adults With Chronic Hepatitis C Virus InfectionCompletedNCT02292719Phase 2Results posted
• A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC)CompletedNCT02291289Phase 2Results posted
• Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal AdenocarcinomaCompletedNCT02289898Phase 2Results posted
• A Study Evaluating Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naïve Participants With Acute Myelogenous LeukemiaCompletedNCT02287233Phase 1/2Results posted
• CPX-351 in Treating Patients With Newly Diagnosed, High-Risk Acute Myeloid LeukemiaCompletedNCT02286726Phase 2Results posted
• T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated CancersCompletedNCT02280811Phase 1/2Results posted
• RDEA3170 and Allopurinol Combination Study in Gout SubjectsCompletedNCT02279641Phase 1Results posted
• A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate TherapyCompletedNCT02277444Phase 3Results posted
• Safety and Efficacy of CC-486 in Previously Treated Patients With Locally Advanced or Metastatic Nasopharyngeal CarcinomaCompletedNCT02269943Phase 2Results posted
• Phase II Decitabine (DAC) Versus Azacitidine (AZA) in Myelodysplastic Syndrome (MDS)CompletedNCT02269280Phase 2Results posted

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