Antimetabolites: all 8,294 studies that test it

Page 83 of 83. Open to participants first (1,149), then studies with results posted, then the rest; newest registration first within each.

• Comparison of ddI Versus Zidovudine in HIV-Infected PatientsCompletedNCT00000979Phase 2
• A Study of Dideoxycytidine Plus Zidovudine in the Treatment of AIDS or Advanced AIDS Related Complex (ARC)CompletedNCT00000978Phase 1
• A Phase I Study of the Safety and Pharmacokinetics of Recombinant Human CD4-Immunoglobulin G (rCD4-IgG) Administered by Intravenous Bolus Injection in Combination With Oral Zidovudine in Patients With AIDS and AIDS-Related ComplexCompletedNCT00000976Phase 1
• The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDSCompletedNCT00000971Phase 1
• The Safety of Zidovudine Plus Interferon-Alpha in HIV-Infected ChildrenCompletedNCT00000967Phase 1
• The Effects of Zidovudine on the Blood of HIV-Infected PatientsCompletedNCT00000965Not applicable
• A Study of Dideoxyinosine (ddI) in HIV-Infected Children Who Have Not Had Success With Zidovudine or Who Cannot Take ZidovudineCompletedNCT00000963Phase 2
• The Safety and Effectiveness of Hyperimmune Anti-HIV Intravenous Immunoglobulin (HVIG) Plus Zidovudine in HIV-Infected InfantsTerminatedNCT00000961Phase 2
• The Safety and Effectiveness of Zidovudine in HIV-Infected Pregnant Women and Their InfantsCompletedNCT00000960Phase 3
• A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their InfantsCompletedNCT00000944Phase 1
• Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIVCompletedNCT00000940Phase 2
• Fortovase (Saquinavir) Given With Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their NewbornsCompletedNCT00000920Phase 1
• A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their BloodCompletedNCT00000916Phase 2
• Addition of Efavirenz or Nelfinavir to a Lamivudine/Zidovudine/Indinavir HIV Treatment RegimenCompletedNCT00000903Phase 3
• Safety and Effectiveness of Giving Indinavir Plus Stavudine Plus Lamivudine to HIV-Infected ChildrenCompletedNCT00000901Phase 1
• A Study to Evaluate the Effects of Different Methods of Birth Control on the Drug Actions of Zidovudine (an Anti-HIV Drug) in HIV-Positive Women and to Compare Zidovudine Metabolism in Men and WomenCompletedNCT00000897Not applicable
• Safety and Effectiveness of Ritonavir Plus Lamivudine Plus Zidovudine in HIV-Infected Pregnant Women and Their BabiesCompletedNCT00000888Phase 1
• A Study to Evaluate the Safety and Tolerance of Nelfinavir (NFV) Given With Zidovudine (ZDV) and Lamivudine (3TC) in HIV-Positive Pregnant Women and Their InfantsCompletedNCT00000887Phase 1
• Virologic and Immunologic Activity of Continued Lamivudine (3TC) vs Delavirdine (DLV) in Combination With Indinavir (IDV) and Zidovudine (ZDV) or Stavudine (d4T) in 3TC-Experienced SubjectsCompletedNCT00000882Phase 2
• A Study to Evaluate the Safety and Tolerance of Stavudine (d4T) in Combination With Lamivudine (3TC) in HIV-Positive Pregnant Women and Their InfantsCompletedNCT00000878Phase 1
• A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected WomenCompletedNCT00000864Phase 1
• A Study of Zidovudine During Labor and Delivery in HIV-Infected Pregnant WomenCompletedNCT00000862Phase 1
• A Study to Evaluate the Safety and Tolerability of Zidovudine (ZDV) in Premature Infants Born to HIV-Positive Women.CompletedNCT00000855Not applicable
• Comparison of Stavudine Used Alone or in Combination With Didanosine in HIV-Infected ChildrenCompletedNCT00000851Phase 2
• A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More MonthsCompletedNCT00000841Phase 3
• A Phase I Trial to Evaluate Didanosine (ddI) in HIV-Infected Pregnant WomenCompletedNCT00000839Phase 1
• Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or DidanosineCompletedNCT00000838Phase 2
• A Phase I Study of Methotrexate for HIV InfectionCompletedNCT00000834Phase 1
• A Phase I Study of Combination Therapy With Didanosine (ddI) and Ribavirin in HIV-Infected Children.CompletedNCT00000833Phase 1
• A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 InfectionCompletedNCT00000823Phase 2
• Evaluation of the Changes in HIV-1 Burden in Peripheral Blood and Lymphoid Tissue Following Zidovudine ( AZT ) Treatment in HIV-1-Infected Patients With CD4+ Cells Between 100 and 500 Cells/mm3.CompletedNCT00000818Phase 1
• A Phase II Double-Blind Study of Delavirdine Mesylate ( U-90152 ) in Combination With Zidovudine ( AZT ) and/or Didanosine ( ddI ) Versus AZT and ddI Combination TherapyCompletedNCT00000803Phase 2
• Methadone Effects on Zidovudine (ZDV, AZT) DispositionCompletedNCT00000800Phase 1
• A Phase II Double-Blind Study of Two Doses of SC-49483 in Combination With Zidovudine (ZDV) Versus ZDVCompletedNCT00000791Phase 2
• A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV InfectionCompletedNCT00000789Phase 2
• A Phase I Open-Label Study of the Safety, Tolerance, and Pharmacokinetic Interactions of Combination Didanosine and Ribavirin in HIV-Positive IndividualsCompletedNCT00000772Phase 1
• A Comparative Study of a Combination of Zidovudine, Didanosine, and Double-Blinded Nevirapine Versus a Combination of Zidovudine and DidanosineCompletedNCT00000770Phase 2
• Pilot Study to Evaluate the Efficacy of Zidovudine in Preventing CD4+ Lymphocyte Decline in Patients With Primary HIV Infection. (One Treatment Arm Receives Placebo)CompletedNCT00000765Not applicable
• A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected WomenCompletedNCT00000758Phase 3
• A Randomized Phase II Study of Two Doses of Interferon Alfa-2a (IFN Alfa-2a) in Combination With Zidovudine (AZT) and Dideoxycytidine (ddC) Versus AZT and ddC Only in Patients With HIV Infection and Less Than 400 CD4 Cells/mm3CompletedNCT00000754Phase 2
• A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)CompletedNCT00000751Phase 3
• A Phase III Study to Evaluate the Safety, Tolerance, and Efficacy of Early Treatment With Zidovudine (AZT) in Asymptomatic Infants With HIV InfectionCompletedNCT00000750Phase 3
• A Phase I Concentration-Controlled Trial to Assess the Safety, Tolerance, Pharmacokinetics and Development of Decreased HIV-1 Susceptibility to the Combination of Atevirdine Mesylate (U-87201E), Zidovudine (AZT), and Didanosine (ddI)CompletedNCT00000742Phase 1
• Safety and Efficacy of Zidovudine for Asymptomatic HIV-Infected IndividualsCompletedNCT00000736Phase 3
• Evaluation of the Interaction Between High Dose Sulfamethoxazole/Trimethoprim and ZidovudineCompletedNCT00000734Not applicable
• Phase I Pharmacokinetic and Tolerance Study of Ribavirin in Human Immunodeficiency Virus (HIV) - Infected PatientsCompletedNCT00000733Phase 1
• Evaluation of the Interaction Between Low Dose Sulfamethoxazole-Trimethoprim and ZidovudineCompletedNCT00000732Not applicable
• Evaluation of the Interaction Between Acetaminophen and ZidovudineCompletedNCT00000731Not applicable
• Phase I Trial of the Combination of Zidovudine and Recombinant Interleukin-2 in Patients With Persistent Generalized LymphadenopathyCompletedNCT00000728Phase 1
• A Double-Blind, Placebo-Controlled Trial To Evaluate Intravenous Gamma Globulin in Children With Symptomatic HIV Infection Receiving ZidovudineCompletedNCT00000720Phase 3
• A Trial of Alternating 2',3'-Dideoxycytidine and Zidovudine in the Treatment of Patients With Advanced HIV DiseaseCompletedNCT00000719Not applicable
• A Multicenter Trial To Evaluate Oral Retrovir in the Treatment of Children With Symptomatic HIV InfectionCompletedNCT00000716Phase 2
• A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3CompletedNCT00000712Phase 2
• Granulocyte-Macrophage Colony-Stimulating Factor and Zidovudine: A Phase I Study of Concurrent Administration in Patients With AIDS and Severe ARCCompletedNCT00000711Phase 1
• A Phase I Safety, Efficacy, and Pharmacokinetic Study of 2',3'-Dideoxyinosine (ddI) Administered Twice Daily to Patients With AIDS or AIDS Related ComplexCompletedNCT00000710Phase 1
• An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte CountsCompletedNCT00000709Phase 3
• Safety and Effectiveness of Azidothymidine (AZT) in HIV-Positive Patients With HemophiliaCompletedNCT00000705Phase 1
• A Multicenter Dose Ranging Clinical Trial of 2',3'-Dideoxycytidine in the Treatment of Patients With AIDS and Advanced ARC.CompletedNCT00000704Phase 1
• A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) InfectionCompletedNCT00000702Phase 3
• A Phase I Evaluation of Azidothymidine (AZT) in Children With Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)CompletedNCT00000701Phase 1
• A Multi-Center Clinical Trial To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients With AIDS Post First Episode PCPCompletedNCT00000700Phase 3
• A Phase I/II Trial of Ribavirin (With Escalation) + Isoprinosine in Asymptomatic HIV-Viremic PatientsCompletedNCT00000699Phase 1
• A Phase I/II Open Label Study To Evaluate the Antiviral Potential of Combination Low-Dose Therapy With Zidovudine and Interferon-Alpha 2A in Patients With Symptomatic HIV DiseaseCompletedNCT00000696Phase 1
• Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDSCompletedNCT00000693Not applicable
• Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's SarcomaCompletedNCT00000687Phase 2
• A Study of d4T in Patients With AIDS or AIDS-Related Complex Who Cannot Take AZTTerminatedNCT00000686Phase 1
• A Study of Zidovudine in HIV-Infected Patients With Kidney ProblemsWithdrawnNCT00000685Phase 1
• A Randomized, Unblinded Trial of Zidovudine Versus ddC in the Treatment of Patients Status Post PCP Who Received Long-Term Zidovudine Therapy in Protocol ACTG 002CompletedNCT00000682Phase 3
• (Ro 24-2027) A Randomized, Double-Blind, Comparative Study of Dideoxycytidine (ddC) Versus Zidovudine (AZT) in Patients With AIDS or Advanced ARCCompletedNCT00000679Phase 2
• Dideoxycytidine ( Ro 24-2027 ) A Randomized, Open-Label, Comparative Study of Dideoxycytidine ( ddC ) Versus Zidovudine ( AZT ) in Patients With AIDS or Advanced ARC Who Have Received Long-Term AZT Therapy.CompletedNCT00000678Phase 2
• An Efficacy Study of 2',3'-Dideoxyinosine (ddI) (BMY-40900) Administered Orally Twice Daily to Zidovudine Intolerant Patients With AIDS or AIDS-Related ComplexCompletedNCT00000672Phase 2
• A Phase II Efficacy Study Comparing 2',3'-Dideoxyinosine (ddI) (BMY-40900) and Zidovudine Therapy of Patients With HIV Infection Who Have Been on Long Term Zidovudine TreatmentCompletedNCT00000671Phase 2
• Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four WeeksCompletedNCT00000670Not applicable
• A Phase I Safety and Pharmacokinetics Study of 2',3'-Dideoxyinosine (ddI) Administered Twice Daily to Infants and Children With AIDS or Symptomatic HIV InfectionCompletedNCT00000669Phase 1
• Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine in HIV Positive, Asymptomatic and Symptomatic IndividualsCompletedNCT00000664Phase 1
• A Treatment IND for Retrovir Brand Zidovudine (AZT) Therapy of Pediatric Patients With HIV DiseaseCompletedNCT00000662Not applicable
• The Pharmacokinetics of Zidovudine and Oxazepam Alone and in Combination in the HIV-Infected PatientCompletedNCT00000661Phase 1
• Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia ComplexCompletedNCT00000657Phase 2
• A Phase I/II, Open Label Study to Evaluate the Antiviral Potential of Combination Zidovudine and 2' 3'-Dideoxyinosine (Didanosine) in Patients With Asymptomatic HIV DiseaseCompletedNCT00000656Phase 1
• A Trial of Two Doses of 2',3'-Dideoxycytidine (ddC) in the Treatment of Children With Symptomatic HIV Infection Who Are Intolerant of AZT and/or Who Show Progressive Disease While on AZTCompletedNCT00000653Phase 2
• A Phase I Study to Evaluate the Safety and Toxicity of the Combination of Zidovudine and 2',3'-Dideoxyinosine (Didanosine) in Children With HIV InfectionCompletedNCT00000652Phase 1
• A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV TherapyCompletedNCT00000651Phase 3
• An Open-Label, Staggered Rising Dose Cohort Study Assessing the Pharmacokinetics, Safety, and Tolerance of BI-RG-587 in Combination With Zidovudine in Patients With HIV Infection (CD4+ Cell Count < 400/mm3)CompletedNCT00000649Phase 1
• An Open Trial Combining Zidovudine, Interferon-alfa, and Recombinant CD4-IgG With Transplantation of Syngeneic Bone Marrow and Peripheral Blood Lymphocytes From Healthy gp160-Immunized Donors in the Treatment of Patients With HIV InfectionCompletedNCT00000647Not applicable
• A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal MeningitisCompletedNCT00000639Not applicable
• A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected ChildrenCompletedNCT00000637Phase 3
• Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical TrifluridineCompletedNCT00000635Not applicable
• The Effects of Valproic Acid on Zidovudine Glucuronidation and Pharmacokinetics in HIV-Infected Patients.CompletedNCT00000629Phase 1
• A Pharmacokinetic Study of L-697,661 Alone and in Combination With ZidovudineCompletedNCT00000628Phase 1
• Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG)CompletedNCT00000602Phase 2
• Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH)CompletedNCT00000586Phase 3
• Glycine and D-Cycloserine in SchizophreniaWithdrawnNCT00000372Phase 3
• Neurobiology of Opioid Dependence: 3 - 3WithdrawnNCT00000194Phase 2
• Fluorouracil Filtering Surgery Study (FFSS)CompletedNCT00000122Phase 3

← Antimetabolites overview