Antimetabolites: all 8,294 studies that test it

Page 19 of 83. Open to participants first (1,149), then studies with results posted, then the rest; newest registration first within each.

• Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS)TerminatedNCT02010645Phase 2Results posted
• Ledipasvir/Sofosbuvir Fixed-Dose Combination Plus Ribavirin in Participants With Chronic HCV With Advanced Liver Disease or Post-Liver TransplantCompletedNCT02010255Phase 2Results posted
• Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and MyelodysplasiaCompletedNCT02007863Not applicableResults posted
• A Study of MabThera/Rituxan (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis and Inadequate Response to DMARD TherapyCompletedNCT02006706Phase 3Results posted
• A Study of Herceptin (Trastuzumab) Combination Therapy in Patients With Metastatic Urothelial CancerCompletedNCT02006667Phase 2Results posted
• Volasertib + Decitabine in Patients With Acute Myeloid Leukemia (AML)TerminatedNCT02003573Phase 1Results posted
• STAR Cape+BKM120 MBC With Brain MetCompletedNCT02000882Phase 2Results posted
• Romidepsin Plus Oral 5-Azacitidine in Relapsed/Refractory Lymphoid MalignanciesTerminatedNCT01998035Phase 1/2Results posted
• A Study of Subcutaneous RoActemra/Actemra (Tocilizumab) as Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Patients With Active Rheumatoid ArthritisCompletedNCT01995201Phase 3Results posted
• Fludarabine / Total Body Irradiation Regimen for ALLO HCT in Acute Lymphoblastic LeukemiaCompletedNCT01991457Phase 2Results posted
• Does Allopurinol Prolong a Treated, Acute Gout Flare?CompletedNCT01988402Phase 4Results posted
• A Study on Safety and Efficacy of Tocilizumab (RoActemra/Actemra) Alone or in Combination With Non-Biologic Antirheumatics in Participants With Rheumatoid ArthritisCompletedNCT01987479Phase 3Results posted
• Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin in Participants With Chronic Genotype 1 HCV Who Participated in a Prior Gilead-Sponsored HCV Treatment StudyCompletedNCT01987453Phase 2Results posted
• Ledipasvir/Sofosbuvir Fixed-Dose Combination With Ribavirin or GS-9669 in Subjects With Chronic Genotype 1 HCV InfectionCompletedNCT01984294Phase 2Results posted
• Aza-SAHA-GBM With AutoSCT for Refractory LymphomaCompletedNCT01983969Phase 1/2Results posted
• Tepotinib With Gefitinib in Participants With Locally Advanced or Metastatic NSCLC (INSIGHT)CompletedNCT01982955Phase 1/2Results posted
• D-Cycloserine Augmentation of Cognitive Behavioral Therapy for DelusionsCompletedNCT01981759Phase 4Results posted
• Novel Use Of Hydroxyurea in an African Region With MalariaCompletedNCT01976416Phase 3Results posted
• Efficacy and Safety of Sofosbuvir/Ledipasvir ± Ribavirin in Japanese Participants With Chronic Genotype 1 HCV InfectionCompletedNCT01975675Phase 3Results posted
• Study of Melphalan HCl for Injection (Propylene Glycol-free), Carmustine, Etoposide, Cytarabine (BEAM Regimen) and Autologous Stem Cell Transplantation for LymphomaCompletedNCT01969435Phase 2Results posted
• Realizing Effectiveness Across Continents With Hydroxyurea (REACH)Active, not recruitingNCT01966731Phase 1/2Results posted
• Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination ± Ribavirin in Cirrhotic Subjects With Chronic Genotype 1 HCV InfectionCompletedNCT01965535Phase 2Results posted
• Chemotherapy for Relapsed Epstein Barr Virus Associated LymphomaTerminatedNCT01964755Phase 2Results posted
• Phase II Clofarabine and Cytarabine for Newly Diagnosed Acute Myeloid LeukemiaTerminatedNCT01960387Phase 2Results posted
• Gemcitabine Hydrochloride, Docetaxel, and Radiation Therapy in Treating Patients With Uterine Sarcoma That Has Been Removed By SurgeryTerminatedNCT01958580Not applicableResults posted
• Sofosbuvir Plus Ribavirin, or Ledipasvir/Sofosbuvir in Adults With HCV Infection and Renal InsufficiencyCompletedNCT01958281Phase 2Results posted
• Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMMLTerminatedNCT01957644Phase 1Results posted
• Study of Trifluridine/Tipiracil (TAS-102) in Patients With Metastatic Colorectal Cancer in AsiaCompletedNCT01955837Phase 3Results posted
• Study of Aflibercept as Maintenance Therapy Following Induction With Aflibercept in Combination With XELOX, as First-Line Treatment for Metastatic Colorectal Cancer PatientTerminatedNCT01955629Phase 1/2Results posted
• Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD PreventionCompletedNCT01951885Phase 3Results posted
• A Clinical Study in Three-arm of Lurbinectedin (PM01183) Alone or in Combination With Gemcitabine and a Control Arm With Docetaxel as Second Line Treatment in Non-Small Cell Lung Cancer (NSCLC) PatientsCompletedNCT01951157Phase 2Results posted
• Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 StudyTerminatedNCT01949870Phase 1Results posted
• Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV MedicationsCompletedNCT01949116Phase 2Results posted
• Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid MalignanciesTerminatedNCT01947140Phase 1/2Results posted
• Short Duration Versus Standard Response-Guided Therapy With Boceprevir Combined With PegIntron and Ribavirin in Previously Untreated Non-Cirrhotic Asian Participants With Chronic HCV Genotype 1 (MK-3034-107)CompletedNCT01945294Phase 3Results posted
• Enhancing Panic and Smoking Reduction Treatment With D-CycloserineCompletedNCT01944423Early Phase 1Results posted
• A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid ArthritisCompletedNCT01941095Phase 3Results posted
• A Multipart, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/r/ABT-267 With and Without ABT-333 Coadministered With and Without Ribavirin in Adult With Genotype 1 or 4 Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 CoinfectionCompletedNCT01939197Phase 2/3Results posted
• Gemcitabine Pharmacokinetics After Preoperative Chemoradiation TherapyTerminatedNCT01938716Not applicableResults posted
• Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder CancerCompletedNCT01938573Phase 1/2Results posted
• Ledipasvir/Sofosbuvir Fixed-Dose Combination + Ribavirin in Subjects With Chronic HCV With Advanced Liver Disease or Post-Liver TransplantCompletedNCT01938430Phase 2Results posted
• Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung CancerTerminatedNCT01935947Phase 2Results posted
• Efficacy and Safety of Combination Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin (RBV) in Genotype 2 Hepatitis C Infection (MK-5172-047)CompletedNCT01932762Phase 2Results posted
• Phase II Study of Capecitabine and Cisplatin to Treat Metastatic Triple Negative Breast CancerStatus unknownNCT01928680Phase 2Results posted
• Phase II Anti-PD1 Epigenetic Therapy Study in NSCLC.CompletedNCT01928576Phase 2Results posted
• D-cycloserine and Treatment of Feeding DisordersCompletedNCT01923896Phase 1/2Results posted
• Radiolabeled Monoclonal Antibody and Combination Chemotherapy Before Stem Cell Transplant in Treating Patients With High-Risk Lymphoid MalignanciesCompletedNCT01921387Phase 1/2Results posted
• Dacomitinib + Pemetrexed for Patients With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)TerminatedNCT01918761Phase 1Results posted
• Study of Gemcitabine, Carboplatin, and Panitumumab (GCaP) as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder CancerTerminatedNCT01916109Phase 2Results posted
• Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)CompletedNCT01912274Phase 2Results posted
• An Open-label, Single Arm, Phase 2 Study to Evaluate ABT-450/r/ABT-267 and ABT-333 With Ribavirin (RBV) in Adults With Genotype 1 HCV Infection Taking Methadone or BuprenorphineCompletedNCT01911845Phase 2Results posted
• Safety and Efficacy of Sofosbuvir Plus Velpatasvir With or Without Ribavirin in Treatment-experienced Subjects With Chronic HCV InfectionCompletedNCT01909804Phase 2Results posted
• Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous LeukemiaCompletedNCT01904136Phase 1/2Results posted
• Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)TerminatedNCT01898793Phase 1/2Results posted
• Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic CancerTerminatedNCT01897454Phase 2Results posted
• Safety and Efficacy Study of Sofosbuvir Plus Ribavirin in Treatment-Naive Adults With Genotype 1 and 3 Chronic HCV InfectionCompletedNCT01896193Phase 3Results posted
• Nab-Pac+Cis+Gem in Pts w Previously Untreated Metastatic PDACompletedNCT01893801Phase 1/2Results posted
• Study of Vosaroxin and Decitabine in Older Patients With Acute Myeloid Leukemia and High-risk Myelodysplastic SyndromeCompletedNCT01893320Phase 1/2Results posted
• Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeCompletedNCT01892371Phase 1/2Results posted
• Capecitabine With Digoxin for Metastatic Breast CancerTerminatedNCT01887288Phase 2Results posted
• Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic LeukemiaActive, not recruitingNCT01885689Phase 2Results posted
• Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)CompletedNCT01881230Phase 2/3Results posted
• Study of Vorinostat in Combination With Gemcitabine and Docetaxel in Advanced SarcomaCompletedNCT01879085Phase 1/2Results posted
• Stem Cell Transplantation for Sickle Cell AnemiaCompletedNCT01877837Phase 3Results posted
• Dasatinib, Cytarabine, and Idarubicin in Treating Patients With High-Risk Acute Myeloid LeukemiaTerminatedNCT01876953Phase 1/2Results posted
• Capecitabine, Cyclophosphamide, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With HER2-Positive Metastatic Breast CancerTerminatedNCT01873833Phase 2Results posted
• Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal CancerTerminatedNCT01871571Phase 2Results posted
• Phase II Trial for Large ER-Negative Breast CancersCompletedNCT01869192Phase 2Results posted
• Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive ChemotherapyCompletedNCT01869114Phase 2Results posted
• Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid TumorsCompletedNCT01862328Phase 1Results posted
• Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC)CompletedNCT01862315Phase 2Results posted
• Neoadjuvant Chemo for Non-metastatic Non-small Cell Lung CancerTerminatedNCT01860040Phase 2Results posted
• Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in ChildrenCompletedNCT01858740Phase 2Results posted
• Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal CarcinomaCompletedNCT01858025Early Phase 1Results posted
• A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTXCompletedNCT01855789Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of Three Experimental Drugs Compared With Telaprevir (a Licensed Product) in People With Hepatitis C Virus Infection Who Have Not Had Treatment BeforeCompletedNCT01854697Phase 3Results posted
• A Study of Pegasys (Peginterferon Alfa-2a) Administered Alone or in Combination With Copegus (Ribavirin) in Patients With Chronic Hepatitis C Who Have Participated in Previous Pegasys TrialsCompletedNCT01853254Phase 3Results posted
• A Study of Decitabine (DACOGEN) in Sequential Administration With Cytarabine in Children With Relapsed or Refractory Acute Myeloid LeukemiaTerminatedNCT01853228Phase 1/2Results posted
• Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)CompletedNCT01851330Phase 3Results posted
• Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic CancerTerminatedNCT01851174Phase 2Results posted
• Non-Myeloablative Conditioning and Bone Marrow TransplantationActive, not recruitingNCT01850108Not applicableResults posted
• Safety, Tolerability, and Efficacy of 12-weeks of Sovaprevir, ACH-3102, and Ribavirin in Treatment-naive GT-1 HCV ParticipantsCompletedNCT01849562Phase 2Results posted
• Metformin+Cytarabine for the Treatment of Relapsed/Refractory AMLTerminatedNCT01849276Phase 1Results posted
• Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid LeukemiaTerminatedNCT01846624Phase 2Results posted
• Trial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)CompletedNCT01845805Phase 2Results posted
• Quinacrine-Capecitabine Combinatorial Therapy for Advanced Stage Colorectal AdenocarcinomaTerminatedNCT01844076Phase 1/2Results posted
• A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic AdenocarcinomaCompletedNCT01839799Phase 2Results posted
• Sofosbuvir Plus Ribavirin Administered for Either 12 or 24 Weeks in Treatment-Naive and Treatment-Experienced Egyptian Adults With Chronic Genotype 4 Hepatitis C Virus (HCV) InfectionCompletedNCT01838590Phase 3Results posted
• Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).CompletedNCT01835587Phase 1/2Results posted
• NMDA Antagonists in Bipolar DepressionCompletedNCT01833897Phase 4Results posted
• Efficacy, Safety and Tolerability of Ribavirin Monotherapy Followed by Combined Treatment With Ribavirin and Hydroxychloroquine in Patients Infected With Hepatitis CTerminatedNCT01833845Phase 1/2Results posted
• A Japanese Phase 1 Trial of TH-302 in Subjects With Solid Tumors and Pancreatic CancerCompletedNCT01833546Phase 1Results posted
• A Study to Evaluate Chronic Hepatitis C Infection in Adults With Genotype 1a InfectionCompletedNCT01833533Phase 3Results posted
• Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromesCompletedNCT01831232Not applicableResults posted
• Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)CompletedNCT01829503Phase 2Results posted
• Methotrexate and Mycophenolate Mofetil for UVEITISCompletedNCT01829295Phase 3Results posted
• Capecitabine Pharmacokinetics(PK)-Actual Versus Ideal Body WeightCompletedNCT01828554Not applicableResults posted
• First Line Gemcitabine, Cisplatin and MEK162 in Advanced Biliary Tract CarcinomaCompletedNCT01828034Phase 1/2Results posted
• Efficacy and Safety of Sofosbuvir Containing Regimens for the Treatment of Chronic HCV Infection in Participants With Chronic Genotype 1, 2, 3, or 6 HCV InfectionCompletedNCT01826981Phase 2Results posted
• Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine TumorsCompletedNCT01824875Phase 2Results posted

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