Drug
Amifostine clinical trials
Also written Ethyol and Ethiofos.
- studies test it
- 36
- open now
- 0
- in phase 3
- 5
- first study started
- 1995
How studies write it
Studies that test it under each name
Studies by the year they started
34 studies that test it; most in 1997 (5)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1996 | 1 |
| 1997 | 5 |
| 1998 | 3 |
| 1999 | 2 |
| 2000 | 1 |
| 2001 | 2 |
| 2002 | 3 |
| 2003 | 4 |
| 2004 | 2 |
| 2005 | 2 |
| 2006 | 3 |
| 2008 | 1 |
| 2010 | 1 |
| 2012 | 1 |
| 2014 | 1 |
| 2018 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 8
- Phase 2
- 23
- Phase 3
- 5
- Phase 4
- 2
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 3 · Other 33
M.D. Anderson Cancer Center (4) · Dana-Farber Cancer Institute (3) · National Cancer Institute (NCI) (3) · Jonsson Comprehensive Cancer Center (2) · University of Alabama at Birmingham (2) · Children's Oncology Group (2) · MedImmune LLC (2) · Mohan Suntharalingam (1)
Often tested with
Tested in the same studies.
Cisplatin (4) · Carboplatin (3) · Vincristine (3) · Filgrastim (3) · Etoposide (2) · Ifosfamide (2) · Cyclophosphamide (2) · Irinotecan (1)
Studies
Open first, then newest update. How each study uses Amifostine is read from its arms, and is right about nine times in ten.
Testing it · 36
- Study of Cytoreductive Surgery and Hyperthermic Intrathoracic Pleural Chemotherapy (HITC) With Escalating Doses for Children and Adolescents With Unilateral Pleural MalignancyCompletedPhase 1M.D. Anderson Cancer CenterNCT01998529Written as Amifostine
- A Study of Amifostine (Ethyol) in Patients With Colorectal CancerTerminatedPhase 2University of CincinnatiNCT00601198Written as Amifostine
- High Dose Chemotherapy With Amifostine and Autologous Stem Cell Transplantation for High Risk Relapsed Pediatric Solid Tumors and Brain TumorsTerminatedPhase 2Children's Hospital Medical Center, CincinnatiNCT05167370Written as Amifostine
- Prospective Study of Head and Neck Cancer Radiation Treatment With or Without AmifostineWithdrawnPhase 4Sun Pharmaceutical Industries LimitedNCT01288625Written as Amifostine
- Amifostine Plus Irinotecan in Treating Patients With Metastatic Colorectal CancerCompletedPhase 1/2Jonsson Comprehensive Cancer CenterNCT00003225Written as amifostine trihydrate
- Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and NeckCompletedPhase 1/2University of Alabama at BirminghamNCT00318890Written as Amifostine
- Radiation-protection Effect of Amifostine in Locally Advanced Rectal CancerStatus unknownPhase 2Fudan UniversityNCT03702985Written as Amifostine
- Amifostine in Treating Patients With Myelodysplastic SyndromeCompletedPhase 2M.D. Anderson Cancer CenterNCT00003048Written as Amifostine Trihydrate
- Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid TumorsTerminatedPhase 1Masonic Cancer Center, University of MinnesotaNCT00003926Written as amifostine trihydrate
- Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & DysphagiaTerminatedPhase 2Vanderbilt-Ingram Cancer CenterNCT00503776Written as amifostine trihydrate
- A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal NeuralgiaTerminatedPhase 3Stanford UniversityNCT01364259Written as Amifostine
- EVALUATION OF AMIFOSTINE FOR MUCOSAL AND HEMOPOETIC PROTECTION AND CARBOPLATIN, TAXOL, RADIOTHERAPY IN THE MANAGEMENT OF PATIENTS WITH HEAD AND NECK CANCER.(GCC 0202)CompletedPhase 2Mohan SuntharalingamNCT00270790Written as Amifostine
- High-dose ICE With AmifostineCompletedPhase 2Dana-Farber Cancer InstituteNCT00003657Written as Amifostine
- Amifostine in Treating Young Patients With Newly Diagnosed De Novo Myelodysplastic SyndromesCompletedPhase 2Children's Oncology GroupNCT00098683Written as amifostine trihydrate
- Amifostine in Treating Patients With Advanced Myelodysplastic SyndromeStatus unknownPhase 2Providence HospitalNCT00003123Written as amifostine trihydrate
- A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal ToxicityStatus unknownPhase 2Chinese Academy of Medical SciencesNCT01586117Written as Amifostine
- Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for CancerCompletedPhase 3Gynecologic Oncology GroupNCT00058071Written as amifostine trihydrate
- Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver CancerCompletedPhase 3Children's Oncology GroupNCT00003994Written as amifostine trihydrate
- Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By SurgeryCompletedPhase 1National Cancer Institute (NCI)NCT00217542Written as amifostine/azacitidine
- Amifostine in Treating Patients With Cancer Who Have Neurological Changes Caused by ChemotherapyCompletedPhase 4Rush North Shore Medical CenterNCT00003252Written as amifostine trihydrate
See all 36 studies that test Amifostine →
Given in every arm · 15 — Amifostine is usual care beside what is tested
- Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast CancerCompletedPhase 1City of Hope Medical CenterNCT00003927Written as amifostine trihydrate
- Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell TransplantationTerminatedPhase 1Eastern Cooperative Oncology GroupNCT00052884Written as amifostine trihydrate
- Amifostine & High-Dose Combination Chemotherapy in Treating Patients With Acute ML or CMLWithdrawnPhase 2Rush University Medical CenterNCT00003407Written as amifostine trihydrate
- Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal CancerCompletedPhase 3Children's Oncology GroupNCT00274937Written as Amifostine
- Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural MesotheliomaCompletedPhase 1Brigham and Women's HospitalNCT00571298Written as amifostine
- Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung CancerCompletedPhase 1/2Alliance for Clinical Trials in OncologyNCT00006012Written as amifostine trihydrate
- Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple MyelomaCompletedPhase 3Fred Hutchinson Cancer CenterNCT00217438Written as amifostine trihydrate
- Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical CancerCompletedPhase 1/2Radiation Therapy Oncology GroupNCT00012012Written as Amifostine trihydrate
- Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung CancerCompletedPhase 3Radiation Therapy Oncology GroupNCT00003313Written as amifostine trihydrate
- Gemcitabine, Cisplatin, and Amifostine Following Surgery in Treating Patients With Locally Advanced Bladder CancerCompletedPhase 2University of ChicagoNCT00006105Written as amifostine trihydrate
- Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous TherapyCompletedPhase 1National Cancer Institute (NCI)NCT00004919Written as amifostine trihydrate
- Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine CytoprotectCompletedPhase 1/2University of KentuckyNCT00003425Written as amifostine trihydrate
- Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Epithelial Ovarian Cancer or Primary Peritoneal CancerCompletedPhase 1/2University of ChicagoNCT00003136Written as amifostine trihydrate
- Paclitaxel and Radiation Therapy Plus Chemoprotection With Amifostine in Treating Patients With Stage III or Stage IV Head and Neck CancerCompletedPhase 1/2Massachusetts General HospitalNCT00003193Written as amifostine trihydrate
- S9720 Combination Chemotherapy in Treating Patients With Metastatic, Recurrent, or Refractory Endometrial CancerCompletedPhase 2SWOG Cancer Research NetworkNCT00003127Written as amifostine trihydrate
As the comparator · 1 — what is tested is compared with Amifostine
Codes
What other systems call Amifostine · ClinicalTrials.gg INT007455
- MeSH (NLM) D004999AmifostineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) M487QF2F4VAMIFOSTINEConfirmed FDA, NLM, Wikidata
- RxNorm 4126Confirmed FDA, Wikidata
- Wikidata Q47495771amifostine trihydrateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C488AmifostineConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D004999 | Amifostine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | M487QF2F4V | AMIFOSTINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 4126 | — | Confirmed FDA, Wikidata |
| Wikidata | Q47495771 | amifostine trihydrate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C488 | Amifostine | Confirmed FDA, Wikidata |
Also registered as amifostine anhydrous (UNII ILA426L95O · RxNorm 1545987) and amifostine monohydrate (UNII L693H6MM64).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.