Alkylating agents: all 3,295 studies that test it
Page 2 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.
- An Umbrella Study of Recurrent, Extensive Stage Small Cell Lung Cancer Based on Molecular TypingNot yet recruitingNCT07141771Phase 1/2
- Anlotinib Hydrochloride Capsules in Maintenance Treatment for Intermediate-High Risk Rhabdomyosarcoma in ChildrenNot yet recruitingNCT07137884Phase 2
- A Study to Evaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or OligodendrogliomaNot yet recruitingNCT07120984Phase 2
- Allogeneic CD7 CAR γδ T Cells Therapy Recurrent/Refractory LeukemiaNot yet recruitingNCT07120607Phase 1
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 1
- Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous DiseaseEnrolling by invitationNCT07113743Phase 1/2
- HS-IT101 Injection for Advanced NSCLC(FASTIL-Lung01)RecruitingNCT07105176Phase 1
- Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)RecruitingNCT07101432Phase 1
- Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin LymphomaRecruitingNCT07097363Phase 2
- GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young AdultsRecruitingNCT07087002Phase 1
- Reduced Intensity Conditioning for MDSNot yet recruitingNCT07085156Phase 2
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune DiseaseRecruitingNCT07085104Phase 1
- Efficacy and Safety of UCBT With TMI -Based Conditioning Regimen for Adults With Refractory/Relapsed Aplastic AnemiaNot yet recruitingNCT07078721Phase 2
- Research on the Application of 68Ga-PSMA-CYC PET Imaging in the Diagnosis, Staging, and Restaging of Prostate CancerRecruitingNCT07056790Phase 1/2
- A Phase II Clinical Study to Evaluate the Efficacy and Safety of Flazoparib Combined With Temozolomide After the Completion of Standard Concurrent Chemoradiotherapy (CCRT) in Newly Diagnosed GlioblastomaNot yet recruitingNCT07047066Phase 2
- Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory NeuroblastomaRecruitingNCT07027748Phase 1
- Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic TransplantationRecruitingNCT07025824Phase 2
- Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual DiseaseRecruitingNCT07025226Early Phase 1
- Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid TumorsRecruitingNCT07010523Not applicable
- Phase II Trial of Zanubrutinib, Obinutuzumab, Bendamustine (ZGB) as First-Line Therapy for Chronic Lymphocytic Leukemia: A Single-Center StudyNot yet recruitingNCT07003464Phase 2
- BrECADD Therapy in Stage 2 B-IV Hodgkin LymphomaRecruitingNCT07002216Phase 2
- Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell TransplantRecruitingNCT06996119Phase 1
- CAR19BCMA CAR-T Cells for the Treatment of R/R Plasma Cell Neoplasms and Lymphomas/Leukemias With Plasmacytic DifferentiationNot yet recruitingNCT06986434Early Phase 1
- Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn DiseaseNot yet recruitingNCT06986382Phase 1/2
- Nivo40-AVD for Advanced Classic Hodgkin LymphomaRecruitingNCT06984146Phase 2
- Safe Effective Therapy With Low-Dose Glucocorticoid in ANCA-Associated Vasculitis (SAFE-LOW)RecruitingNCT06983821Phase 3
- Obinutuzumab With CHOP Versus Obinutuzumab With Bendamustine in the Treatment of Newly Diagnosed Follicular Lymphoma Grade 3ANot yet recruitingNCT06961500Phase 2
- Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient StudyRecruitingNCT06959771Phase 1/2
- Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)Not yet recruitingNCT06954987Phase 2
- Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD)RecruitingNCT06954805Phase 2
- Zanubrutinib Combined With BR in the First-line Treatment of Waldenström's MacroglobulinemiaNot yet recruitingNCT06942507Not applicable
- Study of ABBV-637 or ABBV-155 With ERAS-801 for People With GlioblastomaRecruitingNCT06934889Phase 1
- Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD PreventionRecruitingNCT06926595Phase 2
- Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic MalignanciesRecruitingNCT06904066Phase 1
- Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid LeukemiaRecruitingNCT06871410Phase 1
- Thiotepa Combined With Busulfan and Fludarabine Conditioning Regimen for Haploidentical Hematopoietic Stem Cell Transplantation in Elderly Patients With High-Risk Acute Myeloid LeukemiaRecruitingNCT06869265Phase 2
- FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory RhabdomyosarcomaRecruitingNCT06865664Phase 1
- Embryonal Tumor With Multilayered RosettesRecruitingNCT06861244Phase 2
- Prostate Cryoablation Combined With Metronomic Cyclophosphamide for Metastatic Prostate CancerRecruitingNCT06854250Phase 2
- Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene TherapyEnrolling by invitationNCT06851767Phase 1/2
- IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)RecruitingNCT06849986Phase 2
- CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive LeukemiaRecruitingNCT06847269Phase 2
- Novel Allogenic CD19-targeting CAR-γδT Cell Therapy (QH103E) in r/r NHLRecruitingNCT06838832Phase 1/2
- Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)RecruitingNCT06835049Phase 2
- A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in IndiaRecruitingNCT06831370Phase 4
- Conditioning Regimen of Melphalan-busulfan and Fludarabine: a Randomized Study of Different Dose of MelphalanRecruitingNCT06829472Phase 3
- Early Use of Tacrolimus in HLA-Mismatched Haploidentical Allogeneic Hematopoietic Transplantation With Post-Transplant CyclophosphamideRecruitingNCT06828796Phase 2
- Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing SarcomaRecruitingNCT06827717Phase 2
- Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity ConditioningRecruitingNCT06815003Phase 2
- Human Leukocyte Antigen (HLA) Mismatched Unrelated Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT06809712Phase 1
- Human Leukocyte Antigen (HLA) Mismatched Related Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT06809699Phase 1
- Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell TransplantationRecruitingNCT06807606Phase 2
- Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)RecruitingNCT06802315Phase 2
- Non-Inferiority Study on MRNA-lncRNA Model in Low-Risk Triple-Negative Breast Cancer PatientsNot yet recruitingNCT06795503Phase 3
- Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Colon CancerRecruitingNCT06783491Phase 3
- Chemoablation Or Bladder Resection With Adjuvant Chemotherapy in Recurrent Non-Muscle Invasive Bladder CancerRecruitingNCT06781879Phase 4
- CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic LeukemiaRecruitingNCT06777979Phase 1
- Metronomic Cyclophosphamide With Pembrolizumab in Checkpoint Inhibitor Refractory MelanomaRecruitingNCT06771544Phase 2
- BV in the Treatment of Relapsed/refractory Hodgkin LymphomaNot yet recruitingNCT06761911Phase 4
- A Study of CAR T-Cells in Relapsed/Refractory Hematologic MalignancyRecruitingNCT06756321Early Phase 1
- Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with HemoblastosisRecruitingNCT06756152Phase 2/3
- Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin LymphomaRecruitingNCT06745076Phase 2
- Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment ExhaustionRecruitingNCT06739395Phase 2
- Efficacy of Organoid-Based Chemotherapy Drug Precision Screening to Guide Treatment for Thyroid CancerNot yet recruitingNCT06713057Phase 2
- Irinotecan Liposomes Combined with Temozolomide and Vincristine in the Treatment of Pediatric Patients with Solid TumorsNot yet recruitingNCT06710821Phase 1
- In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE TrialRecruitingNCT06704191Phase 1/2
- Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC PatientsRecruitingNCT06696794Phase 3
- Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer PatientsRecruitingNCT06690840Phase 2
- CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell TransplantRecruitingNCT06687772Phase 2
- Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLCRecruitingNCT06681220Phase 1/2
- Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation SurgeryNot yet recruitingNCT06680245Phase 3
- Phase 1 Dose Escalation and Expansion Study of PRAME T Cell Receptor (TCR) Engineered NK Cells in Participants With Recurrent and/or Refractory Melanoma (PRAMETIME-Mel)RecruitingNCT06660420Phase 1
- Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary BlastomaRecruitingNCT06647953Phase 3
- High-dose Methotrexate Combined with Thiotepa and Zanubrutinib in the Treatment of Newly Diagnosed PCNSL (MTZ)Not yet recruitingNCT06646211Phase 2
- CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular CarcinomaNot yet recruitingNCT06641453Phase 1/2
- Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal FunctionRecruitingNCT06623630Phase 1
- The Efficacy and Safety of Treatment With Telitacicept in Primary Membranous NephropathyNot yet recruitingNCT06614985Phase 2
- Twice-per-weekSelinexor, 2 Days MelphalanNot yet recruitingNCT06613035Phase 3
- Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant DiseaseRecruitingNCT06607458Phase 2
- R-CMOP in Patients With Newly Diagnosed Diffuse Large B-cell LymphomaRecruitingNCT06594640Phase 1/2
- Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WMRecruitingNCT06561347Phase 2
- MRD Guided De-intensification of Bendamustine/Rituximab for Indolent Non-Hodgkin LymphomaNot yet recruitingNCT06557330Phase 2
- A Study of Selinexor in Combination With Temozolomide and Anti-PD-1 Antibody in Patients With Relapsed/Refractory Primary Central Nervous System LymphomaRecruitingNCT06556199Phase 1/2
- A Study of Zanubrutinib in Combination With Polatuzumab Vedotin, Bendamustine and Rituximab in the Treatment of Relapsed/Refractory Diffuse Large B-cell LymphomaRecruitingNCT06554600Phase 2
- Anti-CD19-CAR-T Cells in Subjects with Relapsed/Refractory B Cell MalignanciesRecruitingNCT06532630Early Phase 1
- N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With NeuroblastomaRecruitingNCT06528496Phase 2
- Study to Evaluate the Non-inferiority of Low-dose HIPEC Versus High-dose HIPEC in the Treatment of PMP (HIPEC-PMP)RecruitingNCT06513065Phase 3
- Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCLRecruitingNCT06500273Phase 2
- Bendamustine and Rituximab With or Without Orelabrutinib in MCL TreatmentRecruitingNCT06496308Phase 3
- The Sagittarius TrialRecruitingNCT06490536Phase 3
- BeFluBu vs FluBuRux Conditioning in Haploidentical HCTRecruitingNCT06477549Phase 2
- LCAR-M61S and LCAR-M61D in Treatment of Relapsed/Refractory Multiple MyelomaNot yet recruitingNCT06472479Not applicable
- RIC With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory PTCL.RecruitingNCT06468267Phase 2
- NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) TrialRecruitingNCT06450041Phase 2
- STARLITE for Unresectable High-Grade GliomasRecruitingNCT06428045Phase 1
- Lomustine in Addition to Standard of Care in Patients With MGMT Methylated GlioblastomaRecruitingNCT06419946Phase 3
- Obinutuzumab Combined With Bendamustine in the Treatment of Mature B-cell LymphomaRecruitingNCT06415708Phase 2
- MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.RecruitingNCT06412497Phase 2
- Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent GlioblastomaRecruitingNCT06410248Phase 1
- Sequential Therapies Modeled on Evolutionary Dynamics for Breast CancerRecruitingNCT06409390Phase 2