Vulvodynia clinical trials
The registry lists 117 studies for Vulvodynia across more than 10 countries. 21 are recruiting or about to start. 92 of them are mainly about Vulvodynia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
Université de Sherbrooke (8) · Western Galilee Hospital-Nahariya (7) · William Beaumont Hospitals (5) · University of British Columbia (4) · Uppsala University (3) · University of California, Los Angeles (3) · Centre Hospitalier Universitaire de Besancon (3) · Oregon Health and Science University (3)
What is being tested here
Drugs under test in Vulvodynia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Effectiveness of a Four-Session Focal Shock Wave Therapy Protocol in Women With Vulvodynia · Nantes University Hospital
- Dec 2026IncobotulinumtoxinA for Provoked Vestibulodynia With Overactive Pelvic Floor Muscle Dysfunction · Center for Vulvovaginal Disorders
- Dec 2026A Phase 2 Study to Evaluate the Efficacy and Safety of Pudafensine in Vulvodynia (Provoked Vestibulodynia) · Initiator Pharma
- Dec 2026Vulvodynia Intervention: the Effect of Multimodal Treatment for Provoked Vulvodynia · Karlstad University
- Dec 2026Young Vulvodynia: Effect and Efficacy of Multimodal Treatment. · Region Örebro County
- Jan 2027Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery · University of Miami
- Apr 2027Vestibulectomy Surgical Techniques Comparison Study · Oregon Health and Science University
- May 2027Vaginal Ecosystem and Network in the United States Study · Vaginal Biome Science
- Jun 2027Transcutaneous Genital Nerves Stimulation for the Treatment of Refractory Chronic Pelvic and Genital Pain in Women. · Prof. Dr. med. Marc Possover
- Jul 2027Prospective Data Bank Creation to Study Vaginal Conditions · Texas Tech University Health Sciences Center
Who these studies take
Of the 13 Vulvodynia studies recruiting now, 8 (62%) set no upper age limit and 5 (38%) stop at 75 or younger. 0 (0%) take children under 18. 12 (92%) are for women only and 0 (0%) for men only; 2 (15%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 12 (92%) | 1 (8%) |
| 30 | 13 (100%) | 1 (8%) |
| 40 | 12 (92%) | 1 (8%) |
| 50 | 11 (85%) | 1 (8%) |
| 65 | 9 (69%) | 1 (8%) |
| 75 | 9 (69%) | 1 (8%) |
| 85 | 8 (62%) | 1 (8%) |
Across all 117 studies, recruiting or not: 60% stop at 75 or younger and 54% at 65; 4% take children; 94% are for women only and 0% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Vulvodynia studies take
Of 32 interventional studies with no phase under Vulvodynia, half reached primary completion within 36 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 36 mo16–56 · 32 studies | — | 36 mo16–56 · 32 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Stopped1
- Remote Mindfulness Education PLVTerminatedOct 26, 2026NCT03541512
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 117. Browse all 117 → or search them.
- Integrated Care Pathway for Hormonally Mediated Vestibulodynia: a Feasibility and Acceptability PilotNot yet recruitingNCT07908901Not applicable1 country
- Transcutaneous Genital Nerves Stimulation for the Treatment of Refractory Chronic Pelvic and Genital Pain in Women.Not yet recruitingNCT07884305Not applicable1 country
- A Pilot Study on the Efficacy of Oral Low Dose Naltrexone for VulvodyniaNot yet recruitingNCT07862400Phase 21 country
- CPP Among Somali Women in Norway: SCEDNot yet recruitingNCT07820176Not applicable1 country
- Effectiveness of a Four-Session Focal Shock Wave Therapy Protocol in Women With VulvodyniaRecruitingNCT075537151 country
- Efficacy of Dry Needling in Reducing Pain During Sexual IntercourseRecruitingNCT07534345Not applicable1 country
- Biomodulation and Rehabilitation Interventions to tarGet Pelvic HealthRecruitingNCT06660212Not applicable1 country
- IncobotulinumtoxinA for Provoked Vestibulodynia With Overactive Pelvic Floor Muscle DysfunctionRecruitingNCT07486830Phase 21 country
- Topical Ketotifen 0.25% for Secondary VestibulodyniaRecruitingNCT07257029Phase 21 country
- Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal SurgeryRecruitingNCT07401134Phase 41 country
- Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?RecruitingNCT06999395Not applicable1 country
- Prospective Data Bank Creation to Study Vaginal ConditionsRecruitingNCT018292041 country
- Use of Topical Testosterone and Estrogen vs Estrogen Alone in Vulvodynia: a Randomized Controlled TrialNot yet recruitingNCT07260825Phase 2/31 country
- Vaginal Ecosystem and Network in the United States StudyEnrolling by invitationNCT064727652 countries
- VIBRating vs Traditional Therapy for Treatment of ENTry DyspareuniaRecruitingNCT06840314Not applicable1 country
- Vestibulodynia At High Resolution: Omics Approach to Improve DiagnosisRecruitingNCT068659631 country
- Application of Cheek Acupuncture in Vaginal Tightening SurgeryNot yet recruitingNCT06587711Not applicable1 country
- Light Emitting Diode in the Treatment of VulvodyniaNot yet recruitingNCT06337448Not applicable1 country
- Treatment and Mapping of Impostor PhenomenonRecruitingNCT05805696Not applicable1 country
- Effectiveness of Low-dose Naltrexone in Patients With Different Types of VulvodyniaRecruitingNCT05955313Phase 21 country
- Somatocognitive Therapy in Treatment of Provoked (Localized) Vestibulodynia - Randomized Clinical Trial (ProLoVe Study)RecruitingNCT04613713Not applicable1 country
- A Phase 2 Study to Evaluate the Efficacy and Safety of Pudafensine in Vulvodynia (Provoked Vestibulodynia)Active, not recruitingNCT07391241Phase 21 country
- Remote Mindfulness Education PLVTerminatedNCT03541512Not applicable1 country
- Vestibulectomy Surgical Techniques Comparison StudyActive, not recruitingNCT05343182Not applicable1 country
- Acupuncture in a Multidisciplinary Approach for Vulvodynia and Chronic Pelvic PainCompletedNCT05324280Not applicable1 country
- Lasertherapy for VulvodyniaActive, not recruitingNCT04711369Not applicable1 country
- Young Vulvodynia: Effect and Efficacy of Multimodal Treatment.Active, not recruitingNCT07092332Not applicable1 country
- Vulvodynia Intervention: the Effect of Multimodal Treatment for Provoked VulvodyniaActive, not recruitingNCT06981611Not applicable1 country
- Efficacy of High Intensity Laser for Provoked VestibulodyniaCompletedNCT05597358Not applicable1 country
- Investigating the Effectiveness of PelvicSense(R) on Pain and Sexual Outcomes in Provoked VestibulodyniaCompletedNCT05909514Not applicable1 country
- Vestibulodynia: Understanding Pathophysiology and Determining Appropriate TreatmentsCompletedNCT03844412Phase 21 country
- Multidisciplinary Treatment of Chronic Vulvar PainActive, not recruitingNCT03640624Not applicable1 country
- Vulvodynia Pain ThresholdsTerminatedNCT044612101 country
- Effect of Acupuncture on Patient Vulvodynia OutcomesCompletedNCT03364127Not applicable1 country
- Therapeutic Efficacy of Erbium:YAG Laser in Postpartum Patients With Episiotomy ScarsTerminatedNCT05793476Not applicable1 country
- Analysis of the Understanding of the French Version of the Vulvar Pain Assessment QuestionnaireCompletedNCT06476002Not applicable1 country
- Dry Needling for Provoked VestibulodyniaCompletedNCT05797480Not applicable1 country
- Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and VulvodyniaCompletedNCT061381711 country
- Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling SurgeryCompletedNCT05702827Phase 31 country
- Effect of Spinal Manipulation on Vulvar PainTerminatedNCT04016467Not applicable1 country
- Acupuncture for Vulvodynia: A Pre-pilot StudyCompletedNCT02704234Not applicable1 country
- Effects of Flourish HEC on Localized Provoked VulvodyniaCompletedNCT05478746Not applicable1 country
- Feasibility Study for Provoked VestibulodyniaCompletedNCT05342402Not applicable1 country
- Lipofilling as a Treatment for VestibulodyniaCompletedNCT03431779Not applicable1 country
- Pelvic Floor Myofascia: A New Player Involved in VulvodyniaCompletedNCT053506181 country
- Is Low Level Laser Therapy (LLLT) Effective for Reducing Pain Experienced by Women With Provoked Vestibulodynia?CompletedNCT04234542Not applicable1 country
- Internet-based Treatment for Provoked VestibulodyniaCompletedNCT04045041Not applicable1 country
- A Trial of Intravesical Therapy for Interstitial Cystitis in Patients With Generalized VulvodyniaWithdrawnNCT01048177Phase 21 country
- A Study of the Effects of Topical Capsaicin in the Treatment of Provoked VestibulodyniaTerminatedNCT02854670Phase 2/31 country
- A Pilot Study of the Effects of Botulinum Toxin in the Treatment of Provoked VestibulodyniaCompletedNCT02858219Phase 31 country