Vitamin A Deficiency clinical trials
The registry lists 67 studies for Vitamin A Deficiency across more than 10 countries. 7 are recruiting or about to start. 50 of them are mainly about Vitamin A Deficiency (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-26.
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Who runs them
USDA, Western Human Nutrition Research Center (5) · Johns Hopkins Bloomberg School of Public Health (5) · University of California, Davis (4) · University of Wisconsin, Madison (3) · Swiss Federal Institute of Technology (3) · Wageningen University (3) · Purdue University (3) · Newcastle University (2)
What is being tested here
Drugs under test in Vitamin A Deficiency studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Vitamin A | 2 | 3 | 10 |
| Phentolamine | 1 | 2 | 2 |
| Retinol palmitate | 0 | 0 | 2 |
| Beta Carotene | 0 | 0 | 1 |
| Vitamin E | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Aug 2027OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity · Phase 3 · Opus Genetics, Inc
- Jul 2027Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm Infants · University of Mississippi Medical Center
- Jul 2027Stem Cell Ophthalmology Treatment Study II · MD Stem Cells
- Aug 2027Vitamin A Supplementation in Allogeneic Stem Cell Transplantation. · Children's Hospital Medical Center, Cincinnati
Who these studies take
Of the 6 Vitamin A Deficiency studies recruiting now, 3 (50%) set no upper age limit and 3 (50%) stop at 75 or younger. 2 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (33%) | 2 (33%) |
| 18 | 4 (67%) | 4 (67%) |
| 30 | 4 (67%) | 4 (67%) |
| 40 | 4 (67%) | 4 (67%) |
| 50 | 4 (67%) | 4 (67%) |
| 65 | 3 (50%) | 3 (50%) |
| 75 | 3 (50%) | 3 (50%) |
| 85 | 3 (50%) | 3 (50%) |
Across all 67 studies, recruiting or not: 73% stop at 75 or younger and 73% at 65; 60% take children; 25% are for women only and 0% for men only; 73% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Vitamin A Deficiency studies take
Of 19 interventional studies with no phase under Vitamin A Deficiency, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo7–26 · 19 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 67. Browse all 67 → or search them.
- OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual AcuityRecruitingNCT07140783Phase 31 country
- Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.RecruitingNCT06450925Phase 21 country
- Vitamin A Supplementation and Breast Milk Vitamin A Levels in Mothers of Preterm InfantsNot yet recruitingNCT07736768Not applicable1 country
- Stem Cell Ophthalmology Treatment Study IIRecruitingNCT03011541Not applicable3 countries
- Effect of Vitamin A Supplementation on Idiopathic ScoliosisRecruitingNCT07335991Not applicable1 country
- Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual StimuliRecruitingNCT06961864Not applicable1 country
- Validation and Simplification of the Retinol Isotope Dilution Technique in Burkinabe SchoolchildrenRecruitingNCT067594931 country
- Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual DisturbancesCompletedNCT06349759Phase 31 country
- Effect of Consuming Vitamin A-fortified Sugar on Serum Retinol Levels in ChildrenCompletedNCT07860060Not applicable1 country
- Vitamin A Status in Patients With Vocal Fold LeukoplakiaActive, not recruitingNCT053232921 country
- The Effects of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East MalaysiaCompletedNCT03256123Not applicable1 country
- Knowledge of Students About Vitamin A and Assessment of Eye Manifestations in Quranic Schools (Khalwai) Khartoum State, Sudan 2022CompletedNCT069898791 country
- Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of GhanaCompletedNCT05178407Not applicable1 country
- Egg Intervention During Pregnancy in IndonesiaActive, not recruitingNCT04694235Not applicable1 country
- Prevalence Of Vitamin A Deficiency In Critically Ill Children With Sepsis And Its Association With Clinical OutcomesCompletedNCT063914371 country
- Impact of Food-to-Food Fortified Cereal Products on Diet Quality in Rural Niger VillagesCompletedNCT058939011 country
- Senegal Market Study for Food-to-Food Fortified (F2F) Instant Porridge FloursCompletedNCT058720611 country
- Impact of Food-to-Food Fortified Cereal Products on Diet Quality in Eldoret, KenyaCompletedNCT058826821 country
- Effect Of Multiple Biofortified Food Crops On Micronutrient Status And Immune Function Among Indian Infants and Their MothersActive, not recruitingNCT02648893Not applicable1 country
- Iron and Vitamin A in School ChildrenCompletedNCT04137354Not applicable1 country
- Efficacy of Yellow Cassava to Improve Vitamin A Status of Kenyan School ChildrenCompletedNCT01614483Not applicable1 country
- Single-dose Postpartum Vitamin A Supplementation of Mothers and NeonatesCompletedNCT00198718Phase 2
- Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural BangladeshCompletedNCT00128557Phase 31 country
- Comparison of Different Refraction Measurements in AdultsCompletedNCT044345211 country
- Nutritional Status and Bouillon Use in Northern GhanaCompletedNCT046327711 country
- Efficacy and Safety of Vitamin A Treatment for Children With SepsisStatus unknownNCT04127968Not applicable
- Individualized Dietary Intervention in Breastfeeding Women: Body Weight and Vitamin A StoresCompletedNCT03640104Not applicable1 country
- Anemia in Older AdultsCompletedNCT04820465
- Retinol Status in Preterm Infants and MothersCompletedNCT04780958Not applicable1 country
- Bioefficacy of Beta-cryptoxanthin From Biofortified MaizeStatus unknownNCT04153968Not applicable1 country
- Liver and Bone Retinol Levels in Guatemalan Adolescents and AdultsStatus unknownNCT044382002 countries
- The Efficacy of Pro-vitamin A Biofortified Cassava on Vitamin A Status in Nigerian Preschool ChildrenCompletedNCT02627222Not applicable1 country
- Estimating Average Vitamin A Requirements in Indonesian and American WomenCompletedNCT04123210Not applicable2 countries
- Effects of EED on Zn Absorption and Retention in Children From a Standard DoseCompletedNCT027600952 countries
- The Correlation Between Vitamin A / E Levels and PreeclampsiaStatus unknownNCT03971604Not applicable1 country
- Effects of Fat-soluble Vitamins Supplementation on Common Complications and Neural Development in Very Low Birth Weight InfantsStatus unknownNCT03876704Phase 31 country
- Nutritional Outcomes After Vitamin A Supplementation in Subjects With SCDCompletedNCT03632876Not applicable1 country
- Nutributter Programming to Prevent Undernutrition: an EvaluationCompletedNCT01552512Not applicable1 country
- Sub Regional Micronutrient Survey in EthiopiaStatus unknownNCT033536622 countries
- Using Stable Isotopes to Assess the Effectiveness of Vitamin A Supplementation in CameroonCompletedNCT03383744Not applicable
- Using Stable Isotope Techniques to Monitor and Assess the Vitamin A Status of Children Susceptible to InfectionCompletedNCT02363985Not applicable1 country
- Vitamin A Liver Reserves and Serum Markers of Vitamin A in US Adults at Time of DeathCompletedNCT033050421 country
- Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) MethodCompletedNCT02996513Not applicable1 country
- Efficacy of Biofortified Maize to Improve Maternal and Infant Vitamin A StatusCompletedNCT02804490Phase 31 country
- Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive AgeCompletedNCT00453648Not applicable
- Vitamin A to Reduce HIV in Vaginal Secretions and Prevent Viral TransmissionCompletedNCT00053612Phase 2
- Stopping Postpartum Vitamin A Supplementation: Missing Concealed BenefitCompletedNCT02043223Phase 2/31 country
- Vitamin A Equivalence of the Provitamin A in Biofortified BananasCompletedNCT02702622Not applicable
- Newly Formulated, Extruded Fortified-blended Foods for Food Aid: the MFFAPP Tanzania Efficacy StudyCompletedNCT02847962Not applicable
- Efficacy of Vitamin A in Fortified Extruded Rice in School ChildrenCompletedNCT01199445Early Phase 11 country