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CompletedNCT04820465Updated Mar 29, 2021

Anemia in Older Adults

An observational study in Anemia, Nutritional Deficiency and Inflammation, sponsored by Instituto Nacional de Salud Publica, Mexico. Completed. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-03-29.

Sponsored by Instituto Nacional de Salud Publica, Mexico · Observational

Study type
Observational
Model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
829
Ages
60 Years and older
Sex
All
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Study summary

A cross-sectional study with 829 older Mexican adults were recruited from July to September 2015, from four localities in the southern region of México. Older adults were interviewed at their homes and a fasting blood sample was obtained for analysis of micronutrient status (iron deficiency, vitamin B12 deficiency, folate deficiency, vitamin A deficiency and biomarkers of inflammation). The aim of the study was to identify the main causes of anemia in older adults with higher rates of anemia according to the recent data of the Mexican National Health and Nutrition Survey.

Read the detailed description

A survey with cross-sectional design was applied in 829 older Mexican adults, recruited during the period July to September 2015, from four localities in the southern region of México: including Champotón, Campeche, Mérida, and Valladolid. Older adults were interviewed at their homes to collect nutrition, health, cognitive and dietary information. Anthropometric measures and functionallity tests were also collected. A finger prick capillary blood sample was collected to measure hemoblobin in situ using HemoCue. Anemia was defined according to WHO criteria. A fasting venous blood sample was collected in 803 older adults. Serum was separated and frozen at -20°C to measure ferritin, retinol, vitamin B12, folate, iron, soluble transferrin receptor, C-reactive protein, interleukin 6, alpha glycoprotein 1, hepcidin, erythropoietin in the laboratory of nutrition of the National Institute of Public Health.

The study protocol was approved by Research, Biosecurity and Ethics Committees of the National Institute of Public Health. Participants received a detailed explanation of the study procedures and signed an informed consent form prior to data collection.

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Conditions studied

  • Anemia
  • Nutritional Deficiency
  • Inflammation

Keywords

  • Anemia
  • Older mexican adults
  • Vitamin A deficiency
  • Iron deficiency
  • Vitamin B12 deficiency
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In context

Anemia

1,810 studies on the registry are indexed under Anemia; 215 are open to participants now.

This study's enrollment of 829 is above the median of 270 across 368 observational studies indexed under Anemia.

Browse Anemia studies →

Lead sponsor

Instituto Nacional de Salud Publica, Mexico is the lead sponsor of 31 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
60 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Older adults >=60 years living in urban localities from the southern region of Mexico ( Champotón, Valladolid, Campeche and Yucatán) were visited at their homes. 60% of the total sample were women and the rest men.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Community-dwelling older adults who wish to participate in the study
  • Ambulatory older adultos
  • Older adult with own decision making

Exclusion criteria

Exclusion Criteria:

  • Non demented
  • Non oxygen dependent
  • No disability
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Study design

Observational model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
829 participants (actual)
Patient registry
No

Interventions

  • OtherNon available due to cross-sectional study design

    Non available since this study (survey) has a cross-sectional design

06

What researchers measure

Primary outcomes

  1. Anemia

    Hemoglobin measure in capillary blood sample

    Time frame: July- September 2015

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Gonzalez RP, De la Cruz-Gongora V, Rodriguez AS. Serum retinol levels are associated with cognitive function among community-dwelling older Mexican adults. Nutr Neurosci. 2022 Sep;25(9):1881-1888. doi: 10.1080/1028415X.2021.1913315. Epub 2021 Apr 13. PubMed 33847257 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 29, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04820465
Lead sponsor
Instituto Nacional de Salud Publica, Mexico
Responsible party
Vanessa De la Cruz (Researcher in Medical Science Level D, Instituto Nacional de Salud Publica, Mexico) — Principal investigator
First posted
Mar 29, 2021
Start date
Jul 2015
Primary completion
Sep 2015
Completion
Sep 2015
Last update
Mar 29, 2021

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2021. You cannot join it, but the record below documents what was studied.

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