An interventional study of liquid vinegar and vinegar pill in Visceral Obesity, Tooth Erosion and Insulin Resistance, sponsored by Carol Johnston. Completed. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-08-28.
Sponsored by Carol Johnston · Not applicable, Interventional, and Prevention
The purpose of this study is to test the potential ability of vinegar to significantly decrease visceral fat in healthy adults with "central obesity". During the 8-week trial, participants will either consume a low-dose vinegar pill (control treatment) or a vinegar drink twice per day.
Research Aim and Hypothesis H1 Daily vinegar consumption will be associated with loss in visceral fat (as measured by DXA) after 8 weeks compared to the placebo treatment (low-vinegar pill) in a group of healthy adults with "central obesity".
H2 Daily vinegar consumption will be associated with a decrease in abdominal circumference after 8 weeks compared to the placebo treatment (low-vinegar pill) in a group of healthy adults with "central obesity".
This randomized, placebo-controlled experimental trial will last 8 weeks. At the initial visit (consenting visit lasting about 20 minutes) the participant will sign the consent and complete a short health questionnaire and a short questionnaire on tooth erosion. Body height and weight and waist circumference will also be measured. Qualifying participants will be stratified by gender, age, weight, and waist circumference, then randomized into two groups: the intervention group, vinegar drinks (VIN) or the control group, vinegar pills (CON). The participants will know which treatment they are given but they will not know which group (control vs. placebo) they are in. Those who receive the VIN will be instructed to drink 2 tablespoons of red wine vinegar (provided) mixed with water twice each day for weeks 1 to 8 of the trial. Those in the CON group will be instructed to take one vinegar pill (provided) each day for weeks 1-8 of the trial. Participants will be instructed to maintain their current diet and exercise habits during the study.
294 studies on the registry are indexed under Obesity, Abdominal; 45 are open to participants now.
This study's enrollment of 102 is above the median of 58 across 234 interventional studies indexed under Obesity, Abdominal.
Browse Obesity, Abdominal studies →This is the only study on the registry with Carol Johnston as lead sponsor.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in this arm were instructed to drink 2 tablespoons of red wine vinegar (provided) mixed with water twice each day for weeks 1 to 8 of the trial.
Dietary Supplement: liquid vinegar
Participants in the control group were instructed to take one vinegar pill (provided) each day for weeks 1-8 of the trial.
Dietary Supplement: vinegar pill
6% red wine vinegar (2 tablespoons providing 1.7 g acetic acid)
Also known as: VIN
Apple Cider Vinegar Tablets (1 tablet providing 0.0225 g acetic acid)
Also known as: CON
visceral adiposity
visceral fat as measured by DXA
Time frame: change after 8 weeks of treatment
tooth erosion
dental exam using Basic Erosion Wear Examination (BEWE)
Time frame: change after 8 weeks of treatment
insulin resistance
measurement of insulin resistance using HOMA-IR (fasting glucose and fasting insulin index)
Time frame: change after 8 weeks of treatment
No study locations are listed for this record.
This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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