Thalassemia: all 422 studies
Page 1 of 5. Open to participants first (69), then studies with results posted, then the rest; newest registration first within each.
- Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent β-ThalassemiaRecruitingNCT07884773Phase 3
- Native T1 Mapping and ECV in Chronic Hemolytic AnemiaNot yet recruitingNCT07882303
- Clinical, Economic,and Psychosocial Burden of Thalassemia in SohagNot yet recruitingNCT07796022
- Low-Dose Liposomal Amphotericin B for Invasive Fungal Infection Prophylaxis in Neutropenic ChildrenRecruitingNCT07725263
- Dexamethasone, Intravenous Injection of Human Immunoglobulin, and Increased Infusion of Mononuclear Cells to Reduce Donor Specific Antibodies in Haploidentical Hematopoietic Stem Cell TransplantationNot yet recruitingNCT07698080Phase 2
- Safety and Efficacy of Hemoglobin F Inducers in Patients With Beta ThalassemiaRecruitingNCT07673302Not applicable
- The Effect of Motivational Interviewing on Treatment Adherence and Self-Efficacy Among Omani Adults With ThalassemiaNot yet recruitingNCT07660224Not applicable
- A Study of SNH-119014 in Adult Participants With Non-transfusion-dependent Thalassemia (NTDT)Not yet recruitingNCT07579949Phase 2
- Evaluation of the Quality of Life in Patients With Chronic Iron Overload Due to Hemoglobinopathies in Greece.Not yet recruitingNCT07352878
- Integrative Diagnosis for SCD and Other RADsRecruitingNCT07206095
- The Effect of Laughter Yoga in Beta Thalassaemia Major Patients: a Randomised Controlled TrialNot yet recruitingNCT06980662Not applicable
- A Multiple Ascending Dose Study of 9MW3011 in Patients With Non-transfusion-dependent β-thalassemiaRecruitingNCT06772766Phase 1
- Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemiaRecruitingNCT06734520Not applicable
- Thalassaemia SeverityNot yet recruitingNCT06720480
- A Pilot Study on the Safety and Efficacy of YOLT-204 for Transfusion-Dependent Beta-ThalassemiaNot yet recruitingNCT06678165Early Phase 1
- Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene TherapyEnrolling by invitationNCT06664541
- Evaluation of Recombinant Humanized Anti-CD25 Monoclonal Antibody for Preventing Graft-versus-host Disease After Haploidentical/matched Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients with Transfusion-dependent ThalassemiaRecruitingNCT06657391Phase 2
- Evaluating Safety and Efficacy of Lentiviral-transduced CD34+ HSCs in Β-thalassaemia Patients.RecruitingNCT06655662Phase 1
- A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or ThalassaemiaRecruitingNCT06609226Phase 3
- Psychiatric Problems in Thalassemic ChildrenNot yet recruitingNCT06601556
- Genetic Profile of Alpha Thalassemia Children at Sohag University Hospital .RecruitingNCT06591936
- Adherence of Beta Thalssemia Patients to Oral Chelation TherapyRecruitingNCT06568926Not applicable
- FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare DiseasesRecruitingNCT06539169
- Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta ThalassemiaRecruitingNCT06490627Phase 2
- Inspiratory Muscle Training in Children With Beta ThalasemiaRecruitingNCT06466304Not applicable
- A Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia MajorRecruitingNCT06465550Phase 1
- EKLF Gene Expression in β-thalassemiaNot yet recruitingNCT06440603
- Detection of Krupple Like Factor -1(KLF1/ EKLF) DNA Mutations in Beta Thalassemia PatientsNot yet recruitingNCT06433570
- Thyroid Function , HbA1c in Relation to Ferritin Level in Adullt Patient e B ThalassemiaNot yet recruitingNCT06377865
- ALS20-101 Lentiviral Gene Therapy for Beta ThalassemiaRecruitingNCT06364774Phase 1/2
- A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301Enrolling by invitationNCT06363760
- Long-term Follow-up Study of BHC001 for TDTRecruitingNCT06314529
- Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin LabelingRecruitingNCT06313398Early Phase 1
- Β-Thalassemia Treatment with KL003 Cell InjectionRecruitingNCT06280378Phase 1/2
- A Study of Participants with Β-Thalassemia Treated with Betibeglogene AutotemcelRecruitingNCT06271512
- European Rare Blood Disorders Platform (ENROL)RecruitingNCT06250595
- RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)RecruitingNCT06213402
- Clinical Observation of Luspatercept in Treatment of Chinese Adult β-thalassaemia Patients With TD β-thalassemiaRecruitingNCT06164821Not applicable
- "Iron Overload and Endocrinological Diseases"RecruitingNCT06137079
- Safety and Efficacy of RM-004 Cells for Hemoglobin H-Constant Spring DiseaseRecruitingNCT06107400Early Phase 1
- A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemiaRecruitingNCT06073860
- Bone Denisty Change in Children With Beta Thalassemia MajorNot yet recruitingNCT06069089
- Assessment of Cognitive Function and Quality of Life in Thalassemic Children at Sohag University HospitalNot yet recruitingNCT06058260
- Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem CellsRecruitingNCT06041620Not applicable
- Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing FactorsNot yet recruitingNCT06026839
- Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene TherapyRecruitingNCT05991336
- the Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-ThalassemiaRecruitingNCT05864170Early Phase 1
- Study of the Role of Genetic Modifiers in HemoglobinopathiesRecruitingNCT05799118
- Assessment of Quality of Life in Thalassemic Patients at Assiut University Hospital: A Single-center ExperienceNot yet recruitingNCT05790980
- A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat StudyEnrolling by invitationNCT05777993Phase 4
- Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent β-thalassemiaRecruitingNCT05776173Not applicable
- Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemiaRecruitingNCT05773729Not applicable
- A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent β-Thalassemia [TDT]RecruitingNCT05762510Early Phase 1
- A Study Evaluating the Safety and Efficacy of the GMCN-508A Drug Product in Transfusion-dependent α-Thalassemia ParticipantsRecruitingNCT05757245Phase 1
- Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major PatientsRecruitingNCT05745532Early Phase 1
- A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)RecruitingNCT05736419Phase 2
- Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesRecruitingNCT05635266
- Atrial Fibrillation in Beta-ThalassemiaRecruitingNCT05508932
- Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell DiseaseRecruitingNCT05477563Phase 3
- Thal-Fabs: Reduced Toxicity Conditioning for High Risk ThalassemiaRecruitingNCT05426252Phase 1/2
- Evaluation of Heart Status in Patients of Beta Thalassemia Using EchocardiogramRecruitingNCT04929574
- Association of Hb F Level With Clinical Severity of Beta ThalassemiaRecruitingNCT04917978
- ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic DisordersRecruitingNCT04398628
- Effect of Folic Acid Supplementation in Pregnant Women Having Thalassaemia TraitNot yet recruitingNCT04310059Not applicable
- Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine SupplementationRecruitingNCT04291352Not applicable
- Thrombophilia In Beta ThalassemiaNot yet recruitingNCT04219449
- A Long-term Follow-up Study in Participants Who Received CTX001Enrolling by invitationNCT04208529Phase 3
- Precision Exercise in Children With Malignant HemopathiesRecruitingNCT04090268Not applicable
- Expanded Access to T-cell Depleted Haplo-Identical Stem Cells for Patients Receiving Haplo-Identical and Unrelated Cord Blood TransplantsAvailableNCT01881334
- Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and CanadaCompletedNCT05506358Not applicableResults posted
- PINPOINT: Gaming Technology for SCD PainCompletedNCT04579926Not applicableResults posted
- A Study of IMR-687 in Subjects With Beta ThalassemiaTerminatedNCT04411082Phase 2Results posted
- Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemiaCompletedNCT04364269Phase 2Results posted
- Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx)TerminatedNCT04059406Phase 2Results posted
- Hydroxyurea Therapy: Optimizing Access in Pediatric Populations EverywhereTerminatedNCT03825341Phase 2Results posted
- Pharmacokinetics of Oral Hydroxyurea SolutionCompletedNCT03763656Phase 1/2Results posted
- Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical StudyTerminatedNCT03733249Phase 1/2Results posted
- A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent ThalassemiaActive, not recruitingNCT03692052Phase 2Results posted
- Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young ChildrenCompletedNCT03591575Phase 4Results posted
- Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/2Results posted
- A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT)CompletedNCT03432364Phase 1/2Results posted
- A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-ThalassemiaCompletedNCT03342404Phase 2Results posted
- Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
- Efficacy and Safety of RBCs Derived From Mirasol-treated Whole Blood in Patients Requiring Chronic Transfusion (PRAISE)TerminatedNCT03329404Not applicableResults posted
- A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-ThalassemiaCompletedNCT03207009Phase 3Results posted
- Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible TabletCompletedNCT02993224Phase 2Results posted
- A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 GenotypeCompletedNCT02906202Phase 3Results posted
- An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) ThalassemiaCompletedNCT02604433Phase 3Results posted
- Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood CellsTerminatedNCT02512679Phase 2Results posted
- Allogeneic SCT of CordIn™, in Patients With HemoglobinopathiesTerminatedNCT02504619Phase 1/2Results posted
- HSCT For Patients With High Risk Hemoglobinopathies Using Reduced IntensityCompletedNCT02435901Phase 1/2Results posted
- Decision Aid for Therapeutic Options In Sickle Cell DiseaseCompletedNCT02326597Not applicableResults posted
- Extension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previously Enrolled in A536-04 (A536-06/MK-6143-004)CompletedNCT02268409Phase 2Results posted
- A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell DiseaseCompletedNCT02151526Phase 1/2Results posted
- Phase II Study to Investigate the Benefits of an Improved Deferasirox Formulation (Film-coated Tablet)CompletedNCT02125877Phase 2Results posted
- Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant FailureActive, not recruitingNCT02105766Phase 2Results posted
- The Effect of Rivaroxaban in Sickle Cell DiseaseCompletedNCT02072668Phase 2Results posted
- Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell TransplantTerminatedNCT02065869Phase 1/2Results posted
- Study of Efficacy and Safety of INC424 in Regularly Transfused Patients With Thalassemia.CompletedNCT02049450Phase 2Results posted
- Phase 2 Study of Montelukast for the Treatment of Sickle Cell AnemiaCompletedNCT01960413Phase 2Results posted