Stomatitis, Aphthous clinical trials
The registry lists 63 studies for Stomatitis, Aphthous across more than 10 countries. 17 are recruiting or about to start. 50 of them are mainly about Stomatitis, Aphthous (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
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Who runs them
Cairo University (3) · Qazvin University Of Medical Sciences (2) · National Institute of Dental and Craniofacial Research (NIDCR) (2) · British University In Egypt (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · EMS (2) · Texas A&M University (1) · Wenjie Zheng (1)
What is being tested here
Drugs under test in Stomatitis, Aphthous studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Nov 2026A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers · Misr University for Science and Technology
- Mar 2027Efficacy and Safety of Thalidomide for Pediatric PFAPA Syndrome · Wenjie Zheng
- Apr 2027Observational Study of OROSEDAL in Sore Throat and Minor Oral Lesions · Laboratoires Elerte
- Jul 2027The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa · The Fourth Affiliated Hospital of Zhejiang University School of Medicine
- Nov 2027Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model · University of Fujairah
Who these studies take
Of the 7 Stomatitis, Aphthous studies recruiting now, 3 (43%) set no upper age limit and 2 (29%) stop at 75 or younger. 3 (43%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (43%) | 3 (43%) |
| 18 | 6 (86%) | 6 (86%) |
| 30 | 6 (86%) | 6 (86%) |
| 40 | 6 (86%) | 6 (86%) |
| 50 | 6 (86%) | 6 (86%) |
| 65 | 5 (71%) | 5 (71%) |
| 75 | 5 (71%) | 5 (71%) |
| 85 | 5 (71%) | 5 (71%) |
Across all 63 studies, recruiting or not: 48% stop at 75 or younger and 41% at 65; 37% take children; 3% are for women only and 0% for men only; 37% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Stomatitis, Aphthous studies take
Of 13 interventional studies with no phase under Stomatitis, Aphthous, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo5–19 · 13 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy VolunteersOct 22, 2026NCT07890428
Studies
Recruiting first, then most recently updated. Showing 50 of 63. Browse all 63 → or search them.
- A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy VolunteersNot yet recruitingNCT07890428Phase 11 country
- Sesame Paste for Recurrent Aphthous StomatitisNot yet recruitingNCT07853326Not applicable
- The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral MucosaRecruitingNCT07723612Not applicable1 country
- Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led ModelNot yet recruitingNCT07721090Not applicable
- Observational Study of OROSEDAL in Sore Throat and Minor Oral LesionsRecruitingNCT076203531 country
- Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil DisordersRecruitingNCT056563651 country
- Efficacy and Safety of Thalidomide for Pediatric PFAPA SyndromeNot yet recruitingNCT07476625Not applicable
- Salivary E-cadherin, Calprotectin, and Matrix Metalloproteinase-9 Levels in Recurrent Aphthous StomatitisRecruitingNCT071417581 country
- Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Recurrent Aphthous StomatitisNot yet recruitingNCT06993337Phase 2
- Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental PatientsRecruitingNCT06819033Phase 41 country
- Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous UlcersNot yet recruitingNCT06622213Phase 2
- Efficacy of Thyme Honey in The Management of Oral Aphthous UlcersNot yet recruitingNCT06421038Not applicable1 country
- Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous StomatitisNot yet recruitingNCT06416046Not applicable
- Efficacy and Safety of BALI Association in the Treatment of Aphthous UlcerationsNot yet recruitingNCT05542173Phase 31 country
- α-Mangostin Hydrogel Film With Chitosan Alginate Base for Recurrent Aphthous Stomatitis (RAS)RecruitingNCT06039774Phase 21 country
- The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous UlcerNot yet recruitingNCT06013202Not applicable1 country
- Devintec OR-AT0222 Oral Gel for the Treatment of Canker Sores: A Double Blind, Randomized, Placebo Controlled Clinical InvestigationRecruitingNCT05959824Not applicable1 country
- Luminance RED for Canker SoresWithdrawnNCT04914533Not applicable1 country
- Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous StomatitisCompletedNCT07702474Phase 2
- Comparison of Hypericum Perforatum, Topical Corticosteroids, and Hyaluronic Acid for Recurrent Aphthous StomatitisCompletedNCT06839313Not applicable1 country
- Evaluation of Topical Probiotic Gel Versus Triamcinolone in Minor Recurrent Aphthous UlcersCompletedNCT07672730Phase 41 country
- A Study on Sumac Mouth Rinse for Treating Recurrent Aphthous StomatitisCompletedNCT07229469Not applicable1 country
- Effect of Zinc Oxide Ointment on Recurrent Aphthous StomatitisCompletedNCT07565181Phase 41 country
- Effectiveness and Safety of Lactobacillus Rhamnosus Lcr35® in the Treatment of Recurrent Aphthous StomatitisCompletedNCT02789605Phase 21 country
- Non-Thermal Plasma vs. Low-Level Laser Therapy for Recurrent Oral UlcersCompletedNCT07322666Not applicable1 country
- The Efficacy of Erythropoietin Oral Gel Versus Erythropoietin Mouthwash in the Management of Recurrent Aphthous StomatitisCompletedNCT06923605Phase 41 country
- Effectiveness of Recurrent Aphthous Stomatitis Mouthwash System for the Treatment of Oral UlcersCompletedNCT07121361Not applicable1 country
- Effect of Alum Stone Containing Mucosal Adhesive Patches on Healing of Recurrent Aphthous StomatitisCompletedNCT06960278Early Phase 11 country
- Post-marketing Study for the Evaluation of Profilm Mouth SoresCompletedNCT06741280Not applicable1 country
- Treatment of Aphtous Ulcers With Photodynamic TherapyCompletedNCT06379438Not applicable1 country
- Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous StomatitisStatus unknownNCT05772338Not applicable1 country
- The Salivary and Faecal Microbiome of Recurrent Aphthous Stomatitis Patients Before and After Treatment With ProbioticsCompletedNCT02976922Not applicable1 country
- Corchorus Olitorius Buccal Films for the Treatment of Recurrent Minor Aphthous UlcerationsCompletedNCT05392842Phase 11 country
- Apremilast for RASCompletedNCT03690544Phase 41 country
- Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).CompletedNCT050946871 country
- Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV InfectionCompletedNCT00000790Phase 22 countries
- Hyaluronic Acid in Counteracting Aphthous StomatitisCompletedNCT048844641 country
- Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous StomatitisStatus unknownNCT04710888Phase 21 country
- Safety, Galenic Acceptability and Efficacy of GV-328 Lozenges in Children With Oral AphthosisCompletedNCT04677062Not applicable1 country
- Prevention of Recurrent Aphthous Stomatitis Using VitaminsCompletedNCT00527306Phase 31 country
- Curcumin and Nanocurcumin in Oral Aphthous UlcerCompletedNCT04385979Not applicable1 country
- Topical Hyaluronic Acid and Recurrent Aphthous Stomatitis.CompletedNCT04265001Phase 31 country
- Tokushima Night Guard for Recurrent Aphthous StomatitisCompletedNCT02890524Not applicable1 country
- Niosomal Propolis as Oromucoadhesive Film: In-vitro, Ex-vivo & In-vivo InvestigationsCompletedNCT03615820Phase 11 country
- A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous StomatitisCompletedNCT00315679Not applicable1 country
- Effectiveness and Clinical Mechanism of Huanglian-Jiedu Decoction in Patients With Intense-exuberant Stomach Fire SyndromeStatus unknownNCT03469232Phase 1/21 country
- Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)WithdrawnNCT02535962Phase 2
- Anakinra for Behcet s DiseaseCompletedNCT01441076Phase 1/21 country
- Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser IrradiationCompletedNCT02925182Not applicable
- Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal DiseasesCompletedNCT02920658Phase 21 country