Small Fiber Neuropathy clinical trials
The registry lists 50 studies for Small Fiber Neuropathy across more than 10 countries. 12 are recruiting or about to start. 34 of them are mainly about Small Fiber Neuropathy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Academisch Ziekenhuis Maastricht (5) · Johns Hopkins University (3) · Aalborg University Hospital (3) · Assistance Publique - Hôpitaux de Paris (2) · RWTH Aachen University (2) · Centre Hospitalier Universitaire, Amiens (1) · HOSPITAL BRITANICO DE BUENOS AIRES (1) · Cairo University (1)
What is being tested here
Drugs under test in Small Fiber Neuropathy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Jan 2027Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy · Assistance Publique - Hôpitaux de Paris
- Feb 2027Detection of Small Fiber Neuropathy Using Skin Properties · Brigham and Women's Hospital
- Aug 2027IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 Antibodies · Endeavor Health
- Sep 2027Evaluation of the Prevalence, and Immunological Characteristics of Small Fiber Neuropathy in Patients With Primary Sjögren's Syndrome · Centre Hospitalier Universitaire, Amiens
- Sep 2027Pilot Study to Evaluate Changes in Intra-Epidermal Nerve Fiber Density (IENFD) in Patients With Small-Fiber Neuropathy · TriCity Research Center
Who these studies take
Of the 9 Small Fiber Neuropathy studies recruiting now, 6 (67%) set no upper age limit and 2 (22%) stop at 75 or younger. 0 (0%) take children under 18. 1 (11%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 9 (100%) | 8 (89%) |
| 30 | 9 (100%) | 8 (89%) |
| 40 | 9 (100%) | 8 (89%) |
| 50 | 9 (100%) | 8 (89%) |
| 65 | 8 (89%) | 7 (78%) |
| 75 | 7 (78%) | 7 (78%) |
| 85 | 6 (67%) | 6 (67%) |
Across all 50 studies, recruiting or not: 34% stop at 75 or younger and 18% at 65; 6% take children; 4% are for women only and 0% for men only; 40% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Stopped1
- Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)SuspendedNov 3, 2026NCT06980948
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 50. search them.
- Evaluation of the Prevalence, and Immunological Characteristics of Small Fiber Neuropathy in Patients With Primary Sjögren's SyndromeRecruitingNCT07917442Not applicable1 country
- Magnetic Brain Stimulation in Small Fiber NeuropathyRecruitingNCT07805057Not applicable1 country
- Pilot Study to Evaluate Changes in Intra-Epidermal Nerve Fiber Density (IENFD) in Patients With Small-Fiber NeuropathyEnrolling by invitationNCT07704931Not applicable1 country
- Effect of Tirzepatide on Diabetic Peripheral Sensorimotor NeuropathyNot yet recruitingNCT07706088Phase 4
- Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber NeuropathyRecruitingNCT035090641 country
- IVIG in the Treatment of Autoimmune Small Fiber Neuropathy With TS-HDS, FGFR-3, or Plexin D1 AntibodiesRecruitingNCT04153422Phase 21 country
- Preventing Chemotherapy-induced Peripheral Neuropathy Using PRESIONA Exercise ProgramRecruitingNCT04652609Not applicable1 country
- Detection of Small Fiber Neuropathy Using Skin PropertiesRecruitingNCT047594431 country
- Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and RegistryRecruitingNCT043106441 country
- Characterization and Prediction of Early Onset Diabetic Peripheral NeuropathyRecruitingNCT055461381 country
- IVIG in Painful Sensory NeuropathyNot yet recruitingNCT06183008Phase 4
- Chronic Pain Rehabilitation in Patients With Small Fiber NeuropathyRecruitingNCT05798949Not applicable1 country
- Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)SuspendedNCT06980948Phase 1/21 country
- Chronic Cough and Small Fiber NeuropathyTerminatedNCT03787511Not applicable1 country
- Diagnostic Accuracy of The Water Immersion Wrinkle Test for Small Fiber NeuropathyCompletedNCT072555731 country
- Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental DisordersCompletedNCT056458741 country
- Effects of Virtual Reality-Based Balance Training Compared to Conventional Balance Training to Reduce Risk of Fall in Patients With Diabetic Peripheral Neuropathy: A Randomized Control TrialCompletedNCT06740227Not applicable1 country
- Xanamem™ in Healthy Elderly SubjectsCompletedNCT03830762Phase 11 country
- Diabetes, Falls, and FracturesCompletedNCT053895661 country
- Comparison of Histamine and Local Heating for Evoking the Axon-reflex Flare Response in DiabetesCompletedNCT059210971 country
- Evaluation of Nicotinamide Riboside in Prevention of Small Fiber Axon Degeneration and Promotion of Nerve RegenerationCompletedNCT03912220Phase 21 country
- Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic StudyCompletedNCT059938711 country
- Analysis of Cutaneous Nerve Biopsies in Gastrointestinal Motility DisordersWithdrawnNCT04872452Not applicable1 country
- IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3CompletedNCT03401073Phase 21 country
- The Effect of Transcutaneous Posterior Tibial Nerve Stimulation in Patients With FibromyalgiaCompletedNCT05937711Not applicable1 country
- Biometric and Biological Data for Diagnosis and Therapy of Pain PatientsStatus unknownNCT048357791 country
- Prevalence and Characteristics of Fabry Disease (FD) in Patients With Stroke or Small Fiber NeuropathyCompletedNCT032301491 country
- fMRI-study in Patients With Small Fiber NeuropathyStatus unknownNCT038890801 country
- Cutaneous Silent Period Assessment in Primary Sjögren's SyndromeCompletedNCT053808041 country
- A Study to Evaluate the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber NeuropathyCompletedNCT03304522Phase 24 countries
- Establishing Normative Values for Thermal Detection and Pain Threshold Established by the Psi MethodSuspendedNCT04611048Not applicable1 country
- Assessment of Small Fiber Neuropathy in Rare Diseases Using SudoscanCompletedNCT02985710Not applicable1 country
- Efficacy and Safety Study of BIIB074 in Participants With Small Fiber NeuropathyTerminatedNCT03339336Phase 214 countries
- Small Fiber Assessment by Cutaneous Silent PeriodStatus unknownNCT048638201 country
- Dorsal Root Ganglion Stimulation for the Management of Painful Intractable Small Fibre Neuropathy:Status unknownNCT02435004Not applicable1 country
- Causes Associated With Small Fiber Neuropathy (SFN).Status unknownNCT041702051 country
- Skin Biopsy in the Diagnosis of Small Fiber Neuropathy in Chinese Patients With DiabetesStatus unknownNCT040715351 country
- Titration Study of ABX-1431CompletedNCT03447756Phase 11 country
- Intravenous Immunoglobulin Therapy for Small Fiber NeuropathyCompletedNCT02637700Phase 21 country
- Autofluorescent Flavoprotein Imaging of Intraepidermal Nerve Fibers: a Pilot StudyCompletedNCT02537951Not applicable1 country
- Spinal Cord Stimulation in Small Fibre NeuropathyTerminatedNCT02905396Not applicable1 country
- Efficacy and Safety of Pregabalin in Treatment of Neuropathic Pain in Patients With Idiopathic Small Fiber NeuropathyCompletedNCT02607254Phase 21 country
- Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber NeuropathyCompletedNCT01911975Phase 31 country
- A Pilot Study of Small Fiber Neuropathy Prevalence in Fibromyalgia Patients Compared to Healthy Subjects Using Sudoscan®Status unknownNCT03347669Not applicable1 country
- Evaluation of Pregabalin in Idiopathic Small Fiber NeuropathyTerminatedNCT00787462Not applicable1 country
- Fycompa in Subjects With Small Fiber Neuropathy (SFN)Status unknownNCT02511873Phase 21 country
- Sudoscan in Patients With Autoimmune DisordersCompletedNCT024344581 country
- Diabetes Peripheral Neuropathy and Small-fibre Nerve Damage: A Comparative StudyCompletedNCT011608871 country
- Metanx Effects on Nerve Fiber Density in Neuropathic DiabeticsStatus unknownNCT01503892Not applicable1 country
- Small-fiber Neuropathy in Chronic Kidney DiseaseStatus unknownNCT01078857Not applicable1 country