Sarcoma, Kaposi clinical trials
The registry lists 161 studies for Sarcoma, Kaposi across more than 10 countries. 24 are recruiting or about to start. 108 of them are mainly about Sarcoma, Kaposi (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its narrower condition AIDS-related Kaposi sarcoma too: 174 studies, 25 open.
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Who runs them
National Cancer Institute (NCI) (36) · National Institute of Allergy and Infectious Diseases (NIAID) (17) · AIDS Malignancy Consortium (15) · Alpha Tau Medical LTD. (5) · Sequus Pharmaceuticals (4) · University of California, San Francisco (4) · Washington University School of Medicine (4) · Memorial Sloan Kettering Cancer Center (4)
What is being tested here
Drugs under test in Sarcoma, Kaposi studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nivolumab | 2 | 0 | 6 |
| Propranolol | 2 | 0 | 2 |
| Doxorubicin | 1 | 5 | 9 |
| Liposomal doxorubicin | 1 | 1 | 3 |
| Pomalidomide | 1 | 0 | 3 |
| Paclitaxel | 1 | 1 | 3 |
| Abemaciclib | 1 | 0 | 1 |
| Immunocytokine NHS-IL12 | 1 | 0 | 1 |
| Daratumumab | 1 | 0 | 1 |
| Interleukin 7 | 1 | 0 | 1 |
Drug classes tested here Immune checkpoint inhibitors 2 open · Antimitotic agents 1 open · Angiogenesis inhibitors 10 · Tyrosine kinase inhibitors (TKIs) 9 · Reverse transcriptase inhibitors 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Dec 2026Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT) · Alpha Tau Medical LTD.
- Dec 2026Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIV · National Cancer Institute (NCI)
- Dec 2026AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW) · Implenomics
- Jan 2027Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia · Alpha Tau Medical LTD.
- Feb 2027Pomalidomide Treatment in Patients With Kaposi Sarcoma · National Cancer Institute (NCI)
- Jul 2027Agnostic Therapy in Rare Solid Tumors · Instituto do Cancer do Estado de São Paulo
Who these studies take
Of the 21 Sarcoma, Kaposi studies recruiting now, 11 (52%) set no upper age limit and 1 (5%) stop at 75 or younger. 2 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (5%) | 1 (5%) |
| 18 | 20 (95%) | 20 (95%) |
| 30 | 21 (100%) | 21 (100%) |
| 40 | 20 (95%) | 20 (95%) |
| 50 | 20 (95%) | 20 (95%) |
| 65 | 20 (95%) | 20 (95%) |
| 75 | 20 (95%) | 20 (95%) |
| 85 | 20 (95%) | 20 (95%) |
Across all 161 studies, recruiting or not: 6% stop at 75 or younger and 3% at 65; 13% take children; 0% are for women only and 2% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Sarcoma, Kaposi studies take
Of 22 phase 2 interventional studies under Sarcoma, Kaposi, half reached primary completion within 72 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 72 mo46–84 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 161. Browse all 161 → or search them.
- AYAHIV Role-based Responsibilities for Oncology-focused Workforce (ARROW)RecruitingNCT06004011Not applicable1 country
- Natural History Study of Kaposi SarcomaRecruitingNCT063751221 country
- Pomalidomide and Nivolumab in People With Virus-Associated Malignancies With or Without HIVRecruitingNCT04902443Phase 11 country
- Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi SarcomaRecruitingNCT04941274Phase 1/21 country
- Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseRecruitingNCT033008301 country
- PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi SarcomaRecruitingNCT04303117Phase 1/21 country
- Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and CancerRecruitingNCT000065181 country
- Daratumumab for Relapsed/Refractory Primary Effusion Lymphoma, Plasmablastic Lymphoma, and Multicentric Castleman DiseaseRecruitingNCT05907759Phase 21 country
- A Study of Propranolol to Treat Kaposi SarcomaRecruitingNCT05797662Phase 25 countries
- Precision Imaging to Evaluate Kaposi SarcomaRecruitingNCT06898203Not applicable2 countries
- Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO TrialNot yet recruitingNCT07576725Phase 21 country
- Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)RecruitingNCT07308886Phase 21 country
- A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor CancerRecruitingNCT05859074Phase 11 country
- Disease Evolution and Risk Factors of AIDS-related Prevalent CancersNot yet recruitingNCT07696169
- Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue NeoplasiaRecruitingNCT04534127Not applicable1 country
- Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related CancersRecruitingNCT056635021 country
- Propranolol for the Treatment of Kaposi Sarcoma in AdultsRecruitingNCT06445166Phase 21 country
- Precision Imaging to Evaluate Kaposi Sarcoma (PRIME-KS): A Device Feasibility TrialRecruitingNCT067513551 country
- Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi SarcomaNot yet recruitingNCT05411237Phase 3
- Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.RecruitingNCT03889899Not applicable1 country
- Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced SarcomasRecruitingNCT07066982Phase 1/21 country
- HHV8 and Solid Organ TransplantationRecruitingNCT050811411 country
- A Study of sEphB4-HSA in Kaposi SarcomaRecruitingNCT03993106Phase 21 country
- L19IL2/L19TNF in Skin Cancer PatientsRecruitingNCT05329792Phase 23 countries
- Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMCCompletedNCT055109082 countries
- Trial of Ixazomib for Kaposi SarcomaActive, not recruitingNCT04305691Phase 21 country
- Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi SarcomaActive, not recruitingNCT02659930Phase 11 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- Pomalidomide Treatment in Patients With Kaposi SarcomaActive, not recruitingNCT04577755Phase 21 country
- Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal AnalysisActive, not recruitingNCT047423871 country
- A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's SarcomaTerminatedNCT01412515Phase 21 country
- sEphB4-HSA in Treating Patients With Kaposi SarcomaCompletedNCT02799485Phase 21 country
- Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVActive, not recruitingNCT04514484Phase 11 country
- Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus InfectionCompletedNCT03601806Phase 23 countries
- Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT)Active, not recruitingNCT03737734Not applicable1 country
- Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination Antiretroviral Therapy (cART) Refractory HIV Associated Kaposi SarcomaActive, not recruitingNCT05646082Phase 11 country
- Kaposi Sarcoma Chemotherapy and Research (KS-CARE)Active, not recruitingNCT064807732 countries
- Pembrolizumab Plus Lenvatinib in Previously Treated Classic Kaposi SarcomaWithdrawnNCT05846724Phase 2
- Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryTerminatedNCT02408861Phase 12 countries
- Nelfinavir Mesylate in Treating Patients With Kaposi SarcomaCompletedNCT03077451Phase 23 countries
- Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)TerminatedNCT03886181Not applicable1 country
- Retreatment With Intratumoral Diffusing Alpha Radiation EmittersCompletedNCT04540588Not applicable1 country
- An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)CompletedNCT03157167Phase 11 country
- The Registry of Oncology Outcomes Associated with Testing and TreatmentCompletedNCT040284791 country
- Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and CancerCompletedNCT02595866Phase 11 country
- NT-I7 for Kaposi Sarcoma in Patients With or Without HIVTerminatedNCT04893018Phase 11 country
- Intra-lesional Nivolumab Therapy for Limited Cutaneous Kaposi SarcomaCompletedNCT03316274Early Phase 11 country
- A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's SarcomaCompletedNCT02029430Phase 21 country
- Studies of Human Herpesvirus 8 and Kaposi's Sarcoma in SicilyCompletedNCT003399371 country
- Interleukin-12 in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00019188Phase 1/21 country