AIDS-related Kaposi sarcoma clinical trials
The registry lists 43 studies for AIDS-related Kaposi sarcoma across 9 countries. 2 are recruiting or about to start. 16 of them are mainly about AIDS-related Kaposi sarcoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Cancer Institute (NCI) (12) · AIDS Malignancy Consortium (12) · Case Comprehensive Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · Eastern Cooperative Oncology Group (2) · Roswell Park Cancer Institute (2) · National Institutes of Health Clinical Center (CC) (1) · Dana-Farber Cancer Institute (1)
What is being tested here
Drugs under test in AIDS-related Kaposi sarcoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Liposomal doxorubicin | 1 | 2 | 3 |
| Doxorubicin | 1 | 2 | 3 |
| Paclitaxel | 1 | 2 | 3 |
| Nirogacestat | 1 | 0 | 2 |
| Interleukin-12 | 0 | 0 | 2 |
| Etoposide | 0 | 0 | 2 |
| Sunitinib | 0 | 0 | 2 |
| Semaxinib | 0 | 0 | 2 |
| Docetaxel | 0 | 0 | 2 |
| Thalidomide | 0 | 0 | 2 |
Drug classes tested here Antimitotic agents 1 open · Tyrosine kinase inhibitors (TKIs) 5 · Angiogenesis inhibitors 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
Who these studies take
Of the 1 AIDS-related Kaposi sarcoma studies recruiting now, 1 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (100%) | 1 (100%) |
| 30 | 1 (100%) | 1 (100%) |
| 40 | 1 (100%) | 1 (100%) |
| 50 | 1 (100%) | 1 (100%) |
| 65 | 1 (100%) | 1 (100%) |
| 75 | 1 (100%) | 1 (100%) |
| 85 | 1 (100%) | 1 (100%) |
Across all 43 studies, recruiting or not: 5% stop at 75 or younger and 2% at 65; 9% take children; 0% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting1
- Nirogacestat in Patients With Kaposi SarcomaOct 20, 2026NCT07539454
Studies
Recruiting first, then most recently updated. Showing 43 of 43. search them.
- Nirogacestat in Patients With Kaposi SarcomaRecruitingNCT07539454Phase 21 country
- Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi SarcomaNot yet recruitingNCT05411237Phase 3
- Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMCCompletedNCT055109082 countries
- Evaluation of Advanced HIV Disease Differentiated Care Model in MalawiCompletedNCT05510973Not applicable1 country
- Evaluating Quality of Life in Patients With AIDS-Associated Kaposi Sarcoma Treated With Bleomycin and VincristineCompletedNCT035969181 country
- Doxil/Caelyx BE StudyCompletedNCT05567601Phase 11 country
- NT-I7 for Kaposi Sarcoma in Patients With or Without HIVTerminatedNCT04893018Phase 11 country
- Interleukin-12 in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00019188Phase 1/21 country
- Paclitaxel in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00003008Phase 21 country
- Lenalidomide in Treating Patients With AIDS-Associated Kaposi's SarcomaCompletedNCT01057121Phase 1/21 country
- Detecting Anal and Genital Human Papillomavirus Infection and Squamous Intraepithelial Lesions in HIV-Positive Patients Enrolled in AIDS Cancer Clinical TrialsCompletedNCT006954221 country
- A Study of Selumetinib in Patients With Kaposi's SarcomaTerminatedNCT01752569Phase 1/21 country
- A Phase II Trial of COL-3 in Patients With HIV Related Kaposi's SarcomaTerminatedNCT00020683Phase 21 country
- Imatinib Mesylate in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00090987Phase 21 country
- PTC299 in Treating Patients With HIV-Related Kaposi SarcomaTerminatedNCT00686842Phase 1/21 country
- Bortezomib in Treating Patients With Relapsed or Refractory AIDS-Related Kaposi SarcomaCompletedNCT01016730Phase 11 country
- High-dose ICE With AmifostineCompletedNCT00003657Phase 21 country
- Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent SarcomasCompletedNCT00474994Phase 21 country
- Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced CancerWithdrawnNCT00093678Not applicable
- Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi SarcomaWithdrawnNCT02137564Phase 2
- Liposomal Daunorubicin in Treating Patients With HIV-Related Kaposi's SarcomaTerminatedNCT00427414Phase 12 countries
- A Pilot Study Of the Effects of Highly Active Antiretroviral Therapy on Kaposi's Sarcoma in ZimbabweCompletedNCT00834457Phase 2/31 country
- Sirolimus in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00450320Phase 11 country
- SU5416 in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00005042Phase 21 country
- Valproic Acid in Treating Patients With Kaposi's SarcomaCompletedNCT00075777Not applicable1 country
- Sunitinib Malate in Treating East African Patients With Kaposi SarcomaWithdrawnNCT00521092Phase 2
- Antiviral Therapy in Treating Patients With Slowly Progressing HIV-Related Kaposi's SarcomaStatus unknownNCT00003419Phase 21 country
- Combination Chemotherapy Plus Filgrastim in Treating Patients With Advanced Solid TumorsCompletedNCT00014456Phase 11 country
- Thalidomide in Treating Patients With HIV-Associated Kaposi's SarcomaCompletedNCT00019123Phase 21 country
- Antiviral Therapy in Treating Patients With Kaposi's Sarcoma With or Without HIV InfectionCompletedNCT00019240Phase 21 country
- Liposomal Doxorubicin and Interleukin-12 in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00020449Phase 21 country
- Halofuginone Hydrobromide in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00064142Phase 21 country
- EMD 121974 in Treating Patients With HIV-Related Kaposi's SarcomaTerminatedNCT00006222Phase 11 country
- Liposomal Doxorubicin and PSC 833 in Treating Patients With AIDS-Related Kaposi's Sarcoma or Other Advanced CancersCompletedNCT00003207Phase 11 country
- BMS-275291 in Treating Patients With HIV-Related Kaposi's SarcomaCompletedNCT00024024Phase 1/21 country
- Doxorubicin in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00002985Phase 31 country
- Altretamine and Etoposide in Treating Patients With HIV-Related CancerCompletedNCT00002936Phase 11 country
- Paclitaxel Compared With Doxorubicin in Treating Patients With Advanced AIDS-Related Kaposi's SarcomaCompletedNCT00003350Phase 31 country
- SU5416 in Treating Patients With AIDS-Related Kaposi's SarcomaCompletedNCT00003720Phase 11 country
- MS-275 in Treating Patients With Advanced Solid Tumors or LymphomaCompletedNCT00020579Phase 11 country
- Photodynamic Therapy in Treating Patients With Skin Cancer or Solid Tumors Metastatic to the SkinTerminatedNCT00023790Phase 11 country
- AIDS and Cancer Specimen Bank (ACSB)CompletedNCT005879121 country
- Thalidomide and Docetaxel in Treating Patients With Advanced CancerCompletedNCT00049296Phase 11 country