Prolapse clinical trials
The registry lists 93 studies for Prolapse across more than 10 countries. 9 are recruiting or about to start. 42 of them are mainly about Prolapse (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 4 narrower conditions too, such as Pelvic Organ Prolapse: 708 studies, 106 open.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
NICHD Pelvic Floor Disorders Network (4) · Medstar Health Research Institute (4) · The Cleveland Clinic (4) · Kanuni Sultan Suleyman Training and Research Hospital (3) · Hospices Civils de Lyon (2) · Wake Forest University Health Sciences (2) · Loyola University (2) · pfm medical gmbh (2)
What is being tested here
Drugs under test in Prolapse studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Polyethylene glycol 3350 | 0 | 0 | 1 |
| Nitrofurantoin | 0 | 0 | 1 |
| Estriol | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Jan 2027POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment · Medstar Health Research Institute
- Jun 2027A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas · University of Alabama at Birmingham
- Jul 2027Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery · Meander Medical Center
Who these studies take
Of the 9 Prolapse studies recruiting now, 5 (56%) set no upper age limit and 1 (11%) stop at 75 or younger. 0 (0%) take children under 18. 8 (89%) are for women only and 0 (0%) for men only; 2 (22%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 7 (78%) | 1 (11%) |
| 30 | 7 (78%) | 1 (11%) |
| 40 | 7 (78%) | 1 (11%) |
| 50 | 9 (100%) | 1 (11%) |
| 65 | 8 (89%) | 1 (11%) |
| 75 | 8 (89%) | 1 (11%) |
| 85 | 7 (78%) | 1 (11%) |
Across all 93 studies, recruiting or not: 16% stop at 75 or younger and 8% at 65; 2% take children; 90% are for women only and 0% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Prolapse studies take
Of 37 interventional studies with no phase under Prolapse, half reached primary completion within 36 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 36 mo17–59 · 37 studies | — | 37 mo21–66 · 35 studies |
| Observational | 45 mo16–58 · 14 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- Rectal Prolapse Surgery in Switzerland: Hospital Volume and Patient OutcomesNov 10, 2026NCT07929935
Studies
Recruiting first, then most recently updated. Showing 50 of 93. Browse all 93 → or search them.
- Functional Links Between the Temporomandibular Joint and the Pelvis in GynecologyRecruitingNCT05978414Not applicable1 country
- A Telehealth Intervention to Increase Patient Preparedness for Surgery in LatinasRecruitingNCT06679621Not applicable1 country
- Biological OviTex Versus Synthetic Graft in Robotic Prolapse SurgeryRecruitingNCT06430931Not applicable1 country
- Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in WomenRecruitingNCT058368441 country
- Post-hysterectomy Vaginal Cuff Prolapse RepairRecruitingNCT07174921Not applicable1 country
- Transvaginal Human Acellular Dermal Matrix for Prolapse TreatmentRecruitingNCT06404931Phase 21 country
- Role of Mesh in Laparoscopic Sacropexy Surgical Techniques for the Treatment of Female Genital ProlapseRecruitingNCT067208311 country
- PDS Versus Prolene as Suture Material for Vaginal Sacrospinous HysteropexyRecruitingNCT05964881Not applicable1 country
- Vaginal Native Tissues Repair for Pelvic Organ ProlapseRecruitingNCT03875989Not applicable1 country
- Rectal Prolapse Surgery in Switzerland: Hospital Volume and Patient OutcomesCompletedNCT07929935
- Retrospective Data Analysis PelviGYNious/EndoGYNiousCompletedNCT069277521 country
- Pre-operative Polyethylene Glycol 3350 for Minimally Invasive Urogynecologic SurgeryCompletedNCT06159777Phase 41 country
- Effects of Strength Training on the Gait and Pelvic Floor in Menopausal WomenCompletedNCT07824947Not applicable1 country
- POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse TreatmentActive, not recruitingNCT06634459Not applicable1 country
- REDUCE Trial- Reducing Prolapse RecurrenceActive, not recruitingNCT04880239Not applicable1 country
- Posterior Mesh Fixation at the Levator Ani Level in Apical Pelvic Organ ProlapseCompletedNCT07194343Not applicable1 country
- Assessment of Changes in Vaginal Microbiota Profiles Before and After Vaginal Urogynecologic SurgeryCompletedNCT04301401Not applicable1 country
- Efficacy of IFABONDTM Synthetic Glue for Fixation of Implanted Material in Laparoscopic Sacrocolpopexy: a Prospective Multicenter StudyCompletedNCT02011373Not applicable1 country
- Barbed-suture Efficiency Study for SacrocolpopexyActive, not recruitingNCT05760794Not applicable1 country
- The NeuGuide™ System for Vaginal Colpopexy in the Treatment of Uterine ProlapseCompletedNCT034369793 countries
- Educating Women About Pelvic Floor Disorders During PregnancyCompletedNCT05440539Not applicable1 country
- Clinical Database of Colorectal Robotic SurgeryActive, not recruitingNCT040131521 country
- STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery TrialCompletedNCT04491617Not applicable1 country
- Sacrocolpopexy With Posterior Repair Obstructed Defecation SymptomsCompletedNCT03658395Not applicable1 country
- A New POP (Pelvic Organ Prolapse) Scoring System: Validity and ReliabilityCompletedNCT065207221 country
- Impact of Preop Video on Patient AnxietyActive, not recruitingNCT05633901Not applicable1 country
- Pectopexy Autologous Vs MeshActive, not recruitingNCT06524700Not applicable2 countries
- Concomitant Posterior Colporrhaphy on Bowel Functions in Pelvic Organ Prolapse RepairCompletedNCT061282911 country
- Evaluation of the Safety, Performance, and Tolerability of the Sacromesh® Medical Device in the Treatment of Prolapse by Promontofixation in a Population of Patients Followed Over the Long Term.CompletedNCT066202111 country
- Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic SacrocolpopexyCompletedNCT04440475Not applicable1 country
- Superiority of Perineoplasty as Concomitant Surgical Procedure During Pelvic Organ Prolapse RepairActive, not recruitingNCT057134221 country
- Sacrocolpopexy and Lateral Suspension OperationsActive, not recruitingNCT044103931 country
- Sacrospinous Ligament Fixation and Lateral Suspension OperationsActive, not recruitingNCT040725881 country
- Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of ProlapseCompletedNCT04523298Not applicable1 country
- Evaluation of 3D Translabial Ultrasound Imaging for Pessary Size EstimationCompletedNCT04099121Not applicable1 country
- Evaluation of Neuromuscular Morphometry of the Vaginal WallCompletedNCT063638381 country
- Effects of the Hypopressive Exercises in Women With Pelvic Organ ProlapseCompletedNCT06352112Not applicable1 country
- Operative Time During the Use of the Synthetic Glue IFABONDTM in Laparoscopic SacrocolpopexyCompletedNCT03307824Not applicable1 country
- Early Feasibility Study of the Reia Vaginal PessaryCompletedNCT04275089Not applicable1 country
- What Affects Willingness to Self-manage a Pessary?Status unknownNCT057506151 country
- Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 CystoceleCompletedNCT05474495Not applicable1 country
- Caregiver Support and Post-operative ConvalescenceCompletedNCT048970611 country
- Efficacy Study of Vaginal Mesh for ProlapseCompletedNCT00475540Not applicable1 country
- Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic SurgeryCompletedNCT03287089Phase 41 country
- Clinical and Dynamic Floor MRI Evaluation Before and After Prolapse SurgeryCompletedNCT034000071 country
- Cost-effectiveness Comparison Between Vaginal Versus Robotic Mesh Surgery for Apical Prolapse: Prospective, Cohort StudyCompletedNCT038780561 country
- Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Ventral Rectopexy for Severe Rectal ProlapseCompletedNCT05254860Not applicable
- Evaluation of TP US in Women With ProlapseCompletedNCT038200891 country
- The Effect of Physiotherapy Treatment Following Gynaecological SurgeryCompletedNCT00222326Not applicable1 country
- 3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center StudyStatus unknownNCT04817150Not applicable1 country