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Primary Myelofibrosis clinical trials

The registry lists 625 studies for Primary Myelofibrosis across more than 10 countries. 124 are recruiting or about to start. 269 of them are mainly about Primary Myelofibrosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

ClinicalTrials.gov finds 655 studies for Primary Myelofibrosis. How that becomes 623 here

This page counts the studies the registry files under Primary Myelofibrosis, and those it files under no condition that list Primary Myelofibrosisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 655Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −13List Primary Myelofibrosis as a condition, but the registry did not file them under itMost often written as “Secondary Myelofibrosis” (4), “Myelofibrosis，MF” (2), and “Advanced Myelofibrosis” (1). The registry filed them under other conditions only, most often Myeloproliferative Disorders (8) and Leukemia, Myeloid, Acute (6).
  3. −19Match it another way18 name it in the title and 1 in a keyword.
  4. 623The count on this page3 of them list Primary Myelofibrosis in their own words; the registry filed them under no condition.

Get an email when these change. Save the Primary Myelofibrosis studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Completed
308
Recruiting
101
Terminated
95
Active, not recruiting
50
Withdrawn
28
Not yet recruiting
20

Phase

Phase 2
280
Phase 1
202
Phase 3
58
Early Phase 1
9
Phase 4
4

Where

United States
452
Italy
101
Germany
75
France
72
Canada
63
United Kingdom
61

Who runs them

Fred Hutchinson Cancer Center (32) · M.D. Anderson Cancer Center (32) · City of Hope Medical Center (24) · Novartis Pharmaceuticals (24) · Incyte Corporation (23) · National Cancer Institute (NCI) (17) · John Mascarenhas (11) · Case Comprehensive Cancer Center (11)

What is being tested here

Drugs under test in Primary Myelofibrosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Ruxolitinib7649
Pacritinib5317
Ropeginterferon alfa-2b416
Navtemadlin425
Momelotinib3312
JAK2 Inhibitor TQ05105309
Jaktinib319
Bomedemstat315
Flixebrutinib303
Cyclophosphamide2242

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 21 open · JAK inhibitors 18 open · Antimetabolites 4 open · Alkylating agents 3 open · Calcineurin inhibitors 2 open

Coming up

14phase 3 studies under way
61studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 101 Primary Myelofibrosis studies recruiting now, 83 (82%) set no upper age limit and 13 (13%) stop at 75 or younger. 10 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (7%) take healthy volunteers.

Recruiting studies that take each age, of 101
AgeWomenMen
107 (7%)7 (7%)
1896 (95%)96 (95%)
3098 (97%)98 (97%)
4098 (97%)98 (97%)
5098 (97%)98 (97%)
6599 (98%)99 (98%)
7596 (95%)96 (95%)
8586 (85%)86 (85%)

Across all 625 studies, recruiting or not: 23% stop at 75 or younger and 10% at 65; 21% take children; 0% are for women only and <1% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Primary Myelofibrosis studies take

Of 98 phase 2 interventional studies under Primary Myelofibrosis, half reached primary completion within 66 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 152 mo31–103 · 67 studies——
Phase 1/269 mo52–125 · 26 studies——
Phase 266 mo32–111 · 98 studies32 mo25–66 · 30 studies83 mo42–119 · 68 studies
Phase 339 mo30–68 · 22 studies——
Observational34 mo29–119 · 23 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Stopped1

Newly registered6

Show 1 more

Studies

Recruiting first, then most recently updated. Showing 50 of 625. Browse all 625 → or search them.