Primary Dysautonomias clinical trials
The registry lists 26 studies for Primary Dysautonomias across more than 10 countries. 12 are recruiting or about to start. 1 of them are mainly about Primary Dysautonomias (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 8 narrower conditions too, such as Multiple System Atrophy: 628 studies, 189 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Vanderbilt University Medical Center (3) · Alterity Therapeutics (2) · University Medical Centre Ljubljana (2) · University of Colorado, Denver (1) · CNSystems Medizintechnik GmbH (1) · Copenhagen University Hospital, Hvidovre (1) · SABAMED Medical Center Ltd. (1) · Faizan Ahmed (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Modafinil and Cognitive Function in POTS · Vanderbilt University Medical Center
- Dec 2026Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals · University Medical Centre Ljubljana
- Feb 2027Autoimmune Basis for Postural Tachycardia Syndrome · Vanderbilt University Medical Center
- Jun 2027Continuous and Non-invasive Measurements by Task Force® CORE/CARDIO in Autonomic Function Testing (AFT) · CNSystems Medizintechnik GmbH
- Oct 2027RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome · University Medical Centre Ljubljana
Who these studies take
Of the 8 Primary Dysautonomias studies recruiting now, 2 (25%) set no upper age limit and 4 (50%) stop at 75 or younger. 1 (13%) take children under 18. 1 (13%) are for women only and 0 (0%) for men only; 4 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 6 (75%) | 5 (63%) |
| 30 | 7 (88%) | 7 (88%) |
| 40 | 7 (88%) | 7 (88%) |
| 50 | 7 (88%) | 7 (88%) |
| 65 | 5 (63%) | 5 (63%) |
| 75 | 4 (50%) | 4 (50%) |
| 85 | 4 (50%) | 4 (50%) |
Across all 26 studies, recruiting or not: 42% stop at 75 or younger and 31% at 65; 12% take children; 8% are for women only and 0% for men only; 38% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- NightWare and Cardiovascular Health in Women With PTSDNov 6, 2026NCT07021014
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 26 of 26. search them.
- Exploring Sympathetic Nervous System Function in Individuals With Down SyndromeRecruitingNCT07238465Phase 31 country
- Guanfacine and Cromolyn Sodium for POTS: The DBPOTS TrialNot yet recruitingNCT07757555Early Phase 11 country
- RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia SyndromeNot yet recruitingNCT07837804Not applicable
- Non-invasive Vagus Nerve Stimulation for Chronic Musculoskeletal PainNot yet recruitingNCT07409363Not applicable1 country
- Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive IndividualsRecruitingNCT074824621 country
- Continuous and Non-invasive Measurements by Task Force® CORE/CARDIO in Autonomic Function Testing (AFT)Not yet recruitingNCT05977335
- Autonomic Reactivity and Personalized NeurostimulationRecruitingNCT06863207Not applicable1 country
- Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord InjuryRecruitingNCT05369520Not applicable1 country
- POLish Registry of CArdioneuroablation and CArdioneuromodulationRecruitingNCT071963971 country
- Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE StudyRecruitingNCT062894131 country
- Transcutaneous Spinal Cord Stimulation Home StudyRecruitingNCT06838637Not applicable1 country
- [18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD Vs. MSA and DLB Vs. ADRecruitingNCT06120049Phase 2/31 country
- Autoimmune Basis for Postural Tachycardia SyndromeActive, not recruitingNCT02725060Not applicable1 country
- Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia SyndromeActive, not recruitingNCT021963761 country
- Long COVID Immune ProfilingActive, not recruitingNCT060272551 country
- Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19Active, not recruitingNCT07405515Not applicable1 country
- Modafinil and Cognitive Function in POTSActive, not recruitingNCT01988883Early Phase 11 country
- Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)CompletedNCT06268288Not applicable1 country
- A Biomarker Study of ATH434 in Participants With MSACompletedNCT05864365Phase 21 country
- Study of ATH434 in Participants with Multiple System AtrophyCompletedNCT05109091Phase 26 countries
- Trial to Evaluate the Efficacy and Safety of KM-819 Treatment to Slow the Progression of Multiple System Atrophy (MSA)TerminatedNCT05695378Phase 21 country
- Head-up Tilt Sleeping to Alleviate Orthostatic Hypotension, Supine Hypertension and Nocturia in Parkinson's DiseaseActive, not recruitingNCT05551377Not applicable1 country
- Cardiovascular Effects of Exercise in Patients With Parkinson's DiseaseActive, not recruitingNCT03343574Not applicable1 country
- Long-term Effects of Transcutaneous Vagal Nerve Stimulation on Postural Orthostatic Tachycardia Syndrome (POTS)Status unknownNCT04632134Not applicable1 country
- Orthostatic Intolerance and Hypotension After Administration of Morphine in Patients Prior to Hip or Knee ArthroplastyStatus unknownNCT049022221 country
- Pathophysiologic Hemodynamics After Primary Unilateral Total Hip Arthroplasty in Patients Receiving ACEIs and ARBsStatus unknownNCT048420581 country