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Premenstrual Dysphoric Disorder clinical trials

The registry lists 42 studies for Premenstrual Dysphoric Disorder across more than 10 countries. 10 are recruiting or about to start. 35 of them are mainly about Premenstrual Dysphoric Disorder (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Status

Completed
23
Recruiting
7
Status unknown
5
Terminated
2
Not yet recruiting
2
Enrolling by invitation
1

Phase

Phase 4
7
Phase 2
6
Phase 3
5
Phase 1
2

Where

United States
19
Canada
4
Sweden
4
United Kingdom
3
Egypt
2
Germany
2

Who runs them

University of North Carolina, Chapel Hill (4) · Weill Medical College of Cornell University (2) · Cairo University (2) · Bayer (2) · Johns Hopkins University (2) · Tel-Aviv Sourasky Medical Center (2) · Midwestern University (1) · Pherin Pharmaceuticals, Inc. (1)

What is being tested here

Drugs under test in Premenstrual Dysphoric Disorder studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Sertraline102
Lorundrostat hydrobromide101
Lorundrostat101
Drospirenone and ethinyl estradiol combination002
Pregnanolone002
Flutamide001
Fluoxetine001
Oxytocin011
EE20011
Paroxetine001

Drug classes tested here SSRIs 1 open

Coming up

0phase 3 studies under way
4studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4

Who these studies take

Of the 7 Premenstrual Dysphoric Disorder studies recruiting now, 1 (14%) set no upper age limit and 6 (86%) stop at 75 or younger. 0 (0%) take children under 18. 6 (86%) are for women only and 0 (0%) for men only; 4 (57%) take healthy volunteers.

Recruiting studies that take each age, of 7
AgeWomenMen
100 (0%)0 (0%)
187 (100%)1 (14%)
307 (100%)1 (14%)
407 (100%)1 (14%)
504 (57%)1 (14%)
652 (29%)1 (14%)
751 (14%)1 (14%)
851 (14%)1 (14%)

Across all 42 studies, recruiting or not: 93% stop at 75 or younger and 93% at 65; 2% take children; 95% are for women only and 0% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 42 of 42. search them.