Port-Wine Stain clinical trials
The registry lists 45 studies for Port-Wine Stain across more than 10 countries. 7 are recruiting or about to start. 39 of them are mainly about Port-Wine Stain (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
University of California, Irvine (17) · Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. (4) · Massachusetts General Hospital (3) · Bispebjerg Hospital (2) · University Hospital, Tours (2) · Szeged University (1) · Centre Hospitalier Universitaire de Nice (1) · xjpfW (1)
What is being tested here
Drugs under test in Port-Wine Stain studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Talaporfin | 0 | 0 | 1 |
| Imiquimod | 0 | 0 | 1 |
| Bosentan | 0 | 0 | 1 |
| Brimonidine | 0 | 1 | 1 |
| Sirolimus | 0 | 0 | 1 |
| Ranibizumab | 0 | 0 | 1 |
| Everolimus | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Tolerability of 532 nm Laser Treatment of Port Wine Stains · Massachusetts General Hospital
- Dec 2026AdvaTx Laser Treatment for Vascular Birthmarks · Szeged University
- Jan 2027A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT · Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Who these studies take
Of the 6 Port-Wine Stain studies recruiting now, 2 (33%) set no upper age limit and 4 (67%) stop at 75 or younger. 3 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (50%) | 3 (50%) |
| 18 | 6 (100%) | 6 (100%) |
| 30 | 5 (83%) | 5 (83%) |
| 40 | 5 (83%) | 5 (83%) |
| 50 | 5 (83%) | 5 (83%) |
| 65 | 5 (83%) | 5 (83%) |
| 75 | 4 (67%) | 4 (67%) |
| 85 | 2 (33%) | 2 (33%) |
Across all 45 studies, recruiting or not: 51% stop at 75 or younger and 38% at 65; 67% take children; 0% are for women only and 0% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 45 of 45. search them.
- Vbeam Pro Pulse Dye Laser for the Treatment of Vascular ConditionsEnrolling by invitationNCT07290426Not applicable1 country
- Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric PatientsRecruitingNCT07183644Not applicable1 country
- A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDTRecruitingNCT05171894Phase 21 country
- AdvaTx Laser Treatment for Vascular BirthmarksRecruitingNCT07250945Not applicable1 country
- Tolerability of 532 nm Laser Treatment of Port Wine StainsRecruitingNCT05841628Not applicable1 country
- Comparative of Sequential Application of Pulsed Dye Laser and Potassium-titanyl-phosphate Laser Treatment for Capillary Malformations Versus Single ApplicationRecruitingNCT07015073Not applicable1 country
- Measure of Acceptance of chRonic Visible sKin conditionSRecruitingNCT061039031 country
- French National Cohort of Children With Port Wine StainCompletedNCT01364857Not applicable1 country
- Retrospective Cohort Study on the Impact of PDL Treatment History on the Efficacy of HMME-PDT in Treating PWS ChildrenCompletedNCT068754921 country
- Skin Imaging to Inform Laser TreatmentsTerminatedNCT04336163Not applicable1 country
- A Pilot Study of Hemoporfin PDT in Children(2-7 Years Old) With Port-wine StainCompletedNCT04106258Phase 41 country
- Postmarketing Safety Study of Hemoporfin in Patients With Port Wine StainCompletedNCT03181984Phase 41 country
- KTP Laser vs Pulsed Dye Laser for Port-Wine StainsStatus unknownNCT05771311Not applicable1 country
- Combined Bipolar Radiofrequency&Pulsed Dye Laser TreatmentCompletedNCT01775722Not applicable1 country
- Novel Treatment for Port Wine Stain BirthmarksCompletedNCT01924273Phase 11 country
- A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.CompletedNCT00830466Phase 11 country
- Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy SamplesCompletedNCT02051101Not applicable1 country
- A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.CompletedNCT00800722Phase 11 country
- Measurement Skin Temperature During Pulsed Laser ExposureCompletedNCT00540917Phase 21 country
- Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser TreatmentCompletedNCT017745521 country
- Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging TechnologiesCompletedNCT013335531 country
- Combined Pulsed Dye Laser and Topical Ranibizumab for Treatment of Port Wine Stain BirthmarksWithdrawnNCT00667472Phase 1
- Pilot Study on the Use of the Matrix Radiofrequencyfor Treatment of Port Wine Stain BirthmarksWithdrawnNCT01166919Phase 1
- Combined Use of Pulsed Dye Laser and Topical Antiangiogenic Agents for Treatment of Port Wine Stain BirthmarksWithdrawnNCT00969397Phase 1/2
- Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain BirthmarksCompletedNCT00585247Not applicable1 country
- Optical Clearing of the Skin in Conjunction With Laser TreatmentsCompletedNCT00580736Phase 11 country
- Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain BirthmarksWithdrawnNCT00580944Phase 1
- Dynamic Epidermal Cooling During Pulsed Dye Laser Treatment of Port Wine Stain Birthmark at High FluencesCompletedNCT005403711 country
- Optical Biopsy of Human Skin in Conjunction With Laser TreatmentCompletedNCT005405661 country
- A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular PathologyCompletedNCT04999618Phase 41 country
- The Role of Angiogenesis-related Pathways in the Development of Port Wine StainsCompletedNCT03948997Not applicable
- Effect of Pulsed Dye Laser on Photodynamic Therapy of Port-Wine StainsStatus unknownNCT04536740Not applicable
- A Pilot Study of Hemoporfin PDT in Children With Port-wine StainCompletedNCT03125057Phase 41 country
- Pilot Study to Evaluate the Effect of Multiple Passes on Port Wine Stain Treatments With the Cutera Excel V™ Laser.SuspendedNCT04103164Not applicable1 country
- Onreltea (Brimonidine) Gel In Pediatric Patients With Capillary MalformationsTerminatedNCT02764411Phase 31 country
- Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot StudyCompletedNCT02317679Phase 21 country
- Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical SirolimusTerminatedNCT02214706Not applicable1 country
- Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)WithdrawnNCT01997255Phase 21 country
- Effect of Laser Treatment on Capillary MalformationsWithdrawnNCT020353191 country
- Treatment of Nevus Flammeus With Alexandrite LaserCompletedNCT01968681Not applicable1 country
- Personalized Interactive Laser Therapy of Port Wine StainTerminatedNCT00782483Not applicable1 country
- Optical Frequency Domain Imaging (OFDI) in DermatologyWithdrawnNCT014380471 country
- The Angioma's Treatment Evaluation With Laser Doppler Imaging (LDI)Status unknownNCT01759082
- Treatment of Naevus Flammeus Using Intense Pulsed Light and Pulsed Dye LaserCompletedNCT00365118Not applicable1 country
- Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE PlatformStatus unknownNCT00247299Not applicable1 country