Pleural Effusion, Malignant: all 169 studies
Page 1 of 2. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.
- A Study to Establish the Diagnostic Value of the EPISEEK-MPE Liquid Biopsy Assay to Identify Cancer in Pleural Effusion Samples.RecruitingNCT07929584
- Union-LC-MPE Cohort:A Multicenter Cohort Study on Diagnosis and Prognosis of Malignant Pleural Effusion in Lung CanceNot yet recruitingNCT07882758
- Cancer Ratio and Cancer Ratio Plus in Malignant and Tuberculous Pleural EffusionsNot yet recruitingNCT07766876
- Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural EffusionRecruitingNCT07726784Not applicable
- Xuan Yin Ning Plus Bevacizumab for Malignant Pleural EffusionNot yet recruitingNCT07670338Not applicable
- A Phase II Study to Evaluate JMKX000197 Injection Versus Cisplatin in the Treatment of Malignant Pleural EffusionNot yet recruitingNCT07649369Phase 2
- Ex Vivo Drug Response Profiling and Outcome Prediction in Lung AdenocarcinomaRecruitingNCT07636252
- WSK-IM02 in Advanced Solid Tumors With Malignant Effusions (Phase I)Not yet recruitingNCT07615894Phase 1
- Furmonertinib Plus Radiotherapy for EGFR+ NSCLC With Pleural EffusionNot yet recruitingNCT07482605Phase 2
- Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary TumorsRecruitingNCT07443020Phase 1
- First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural EffusionRecruitingNCT07332858Phase 1/2
- Pleurodesis in Small-bore Chest TubeNot yet recruitingNCT07208409Not applicable
- Fast TILs to Treat Metastatic Cancer Patients With Pleural DiseaseRecruitingNCT07192900Phase 1
- Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in PleurodesisNot yet recruitingNCT07167992Not applicable
- Impact of Patient Position on Chemical Pleurodesis by Chest UltrasoundRecruitingNCT07147270Not applicable
- Effectiveness of Intercostal Tube Drainage Vs Pigtail Catheter Drainage Vs Ultrasound-Guided Aspiration in Management of Massive Malignant Pleural EffusionNot yet recruitingNCT06964321Not applicable
- ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNGRecruitingNCT06959719Not applicable
- First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.RecruitingNCT06946498Not applicable
- The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural EffusionNot yet recruitingNCT06742099Early Phase 1
- A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural EffusionRecruitingNCT06740019Phase 1
- A Study of MT027 in Patients with Pleural Malignant TumorsRecruitingNCT06726564Phase 1
- Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural EffusionNot yet recruitingNCT06691009Not applicable
- Clinical Study on Intraluminal Injection of FOLactisRecruitingNCT06512896Not applicable
- OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.RecruitingNCT06421610Phase 1
- Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective StudyNot yet recruitingNCT06275178
- Safety and Efficacy of NK510 to Treat NSCLCRecruitingNCT06097962Early Phase 1
- Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic CancerRecruitingNCT06016179Phase 1
- A Prospective Observational Study on the Role of Transthoracic Ultrasound in Differentiating Tuberculous From Malignant Pleural EffusionRecruitingNCT05935696
- A Phase I Study of JMKX000197 Injection in the Treatment of Malignant Pleural EffusionRecruitingNCT05923515Phase 1
- Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural InterventionRecruitingNCT05910112
- Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)RecruitingNCT05872126Not applicable
- Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural EffusionNot yet recruitingNCT05693727
- UNC Pleural Fluid RegistryRecruitingNCT05620329
- A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLCRecruitingNCT05543330Phase 1/2
- IFN-γ Combined With T Cells in the Treatment of Refractory Malignant Pleural Effusion and AscitesRecruitingNCT05268172Phase 1
- Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study.RecruitingNCT04806412Not applicable
- Dual-targeting HER2 and PD-L1 CAR-T for Solid TumorsRecruitingNCT04684459Early Phase 1
- Longitudinal Follow up of Patients With Pleural EffusionRecruitingNCT04670562
- Biomarker Levels During Indwelling Pleural cAtheter Sample TestingEnrolling by invitationNCT02092155
- Randomized Controlled Trial of Talc Instillation In Addition To Daily Drainage Through a Tunneled Pleural Catheter to Improve Rates of Outpatient Pleurodesis in Patients With Malignant Pleural EffusionTerminatedNCT04792970Phase 4Results posted
- A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural EffusionTerminatedNCT03597009Phase 1/2Results posted
- Safety and Effectiveness of a New Pleural Catheter for Symptomatic, Recurrent, MPEs Versus Approved Pleural CatheterCompletedNCT02649894Not applicableResults posted
- Indwelling Pleural Catheter With Either Doxycycline or Saline at Day 7 for PleurodesisTerminatedNCT02623959Phase 4Results posted
- Genetic Sequencing-Informed Targeted Therapy in Treating Patients With Stage IIIB-IV Non-small Cell Lung CancerTerminatedNCT02132884Not applicableResults posted
- Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal CancerCompletedNCT02122185Phase 2Results posted
- Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)CompletedNCT01999985Phase 1Results posted
- Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung CancerCompletedNCT01661790Phase 3Results posted
- Romidepsin and Erlotinib Hydrochloride in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerCompletedNCT01302808Phase 1Results posted
- Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung CancerTerminatedNCT01004510Phase 2Results posted
- Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian CancerCompletedNCT00993655Phase 2Results posted
- Anemia Treatment for Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Receiving ChemotherapyTerminatedNCT00858364Phase 3Results posted
- QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung CancerTerminatedNCT00791154Phase 1/2Results posted
- Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the PleuraTerminatedNCT00601848Phase 2Results posted
- FDG-Labeled PET Scan in Planning Chemotherapy in Treating Patients With Stage IIIB or IV Non-Small Cell Lung CancerCompletedNCT00564733Phase 2Results posted
- AZD0530 in Treating Patients With Extensive Stage Small Cell Lung CancerCompletedNCT00528645Phase 2Results posted
- Single Agent Alimta in Poor Performance Status in Non-small Cell Lung CancerCompletedNCT00508144Phase 2Results posted
- Imatinib Mesylate and Paclitaxel in Treating Older Patients With Stage IIIB or Stage IV Non-Small Cell Lung CancerCompletedNCT00408460Phase 2Results posted
- A Study of Cetuximab and Bevacizumab in Combination With Paclitaxel and Carboplatin in Stage IIIb/IV NSCLCCompletedNCT00343291Phase 2Results posted
- Phase II Study of Docetaxel + ZD1839 in Elderly Patients With Non-Small Cell Lung CancerCompletedNCT00231465Phase 2Results posted
- The 'MADe IT' Clinical Trial: Molecular Analyses Directed Individualized Therapy for Advanced Non-Small Cell Lung CancerCompletedNCT00215930Phase 2Results posted
- Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung CancerCompletedNCT00126581Phase 2Results posted
- Synchronous Bilateral Talc PleurodesisCompletedNCT07810049
- Impact of Pleural Manometry on the Assessment and Treatment of Malignant Pleural Effusion: A Pilot Clinical TrialCompletedNCT07120867Not applicable
- Thoracoscopic Talc Pleurodesis Versus Bleomycin -Tranxemic Acid Mixture Injection in Chest Tube in Malignant Pleural EffusionCompletedNCT06744946Phase 4
- Quantitative C-Reactive Protein for Differentiating Tuberculous and Malignant Pleural Effusion: a Cross-Sectional StudyCompletedNCT06729931
- Feasibility of Ambulatory Talc. PleurodesisCompletedNCT06682936Not applicable
- Cytological Examination of Malignant Pleural Effusion in Breast CancerCompletedNCT06657638
- PMCF Study of the CE-marked Drainova® ArgentiC CatheterCompletedNCT06436807
- The ACES Study for Aseptic Pleural EffusionActive, not recruitingNCT06210685Not applicable
- Safety and Efficacy Study of Virus Activated Killer Immune Cells (VAK) for Malignant Pleural and Peritoneal EffusionStatus unknownNCT05565014Early Phase 1
- Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)CompletedNCT05461430
- Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing MesothelinWithdrawnNCT05375825Phase 1
- Malignant Pleural Effusions: Evaluating the psYchosocial Impact of Indwelling Pleural Catheters on PatientsCompletedNCT05372055
- A Study of Intrapleural Administration of Bevacizumab and Camrelizumab for Malignant Pleural EffusionStatus unknownNCT05330065Phase 1/2
- Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural EffusionStatus unknownNCT05291403Not applicable
- Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including MesotheliomaCompletedNCT05278975Phase 1/2
- A Multicenter Survey Study Into Patient Experience With Mobile AppsStatus unknownNCT05130697
- A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General AnesthesiaStatus unknownNCT05077111Phase 4
- Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to DrugsWithdrawnNCT04985357
- A Phase Ⅲ Clinical Study of Combined Cisplatin Versus Placebo Combined With Intracavitary Cisplatin Injection in the Treatment of Malignant Pleural EffusionsActive, not recruitingNCT04914598Phase 3
- Pleural Carcinomatosis Tissue BankingCompletedNCT04844827
- Interventions for Malignant Pleural Effusions Impact on FatigueStatus unknownNCT04793607
- Intrapleural Instillation of the Nivolumab in Cancer Patients With Pleural Effusion.CompletedNCT04749602Phase 2
- Comparing Different Sizes of Small-bore Chest Drains in Malignant Pleural EffusionTerminatedNCT04669223Not applicable
- AMPLE-3: IPC Plus Talc vs VATS in Management of Malignant Pleural EffusionCompletedNCT04322136Not applicable
- Quantitative Diaphragmatic Ultrasound Evaluation in Pleural Effusions : A Feasability StudyCompletedNCT04264325
- Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural TapStatus unknownNCT04254445Not applicable
- Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the PleuraTerminatedNCT04236037Not applicable
- Value of Additional Upfront Systematic Lung Ultrasound in the Workup of Patients With Unilateral Pleural EffusionCompletedNCT04235998
- A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer.TerminatedNCT04233359Not applicable
- Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural EffusionStatus unknownNCT04131231Not applicable
- A Phase I Study Evaluating SCB-313(Recombinant Human TRAIL-Trimer Fusion Protein) for the Treatment of Malignant Pleural EffusionCompletedNCT04123886Phase 1
- Comparison of the Effectiveness of Povidone-Iodine Alone to Povidone-Iodine-Tetracycline CombinationStatus unknownNCT04039126Phase 1
- A Randomized Study of Primary Tumor Radiotherapy for Patients With MPE Stage IV NSCLCStatus unknownNCT03987087Phase 2
- Talc Outpatient Pleurodesis With Indwelling CatheterStatus unknownNCT03973957Not applicable
- Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural EffusionsCompletedNCT03869697Phase 1
- Management of Malignant Pleural Effusion With Indwelling Pleural Catheter Versus Silver Nitrate PleurodesisStatus unknownNCT03781908Phase 1/2
- A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant AscitesStatus unknownNCT03736122Phase 1/2
- Respiratory Function of Dexmedetomidine in Patients Undergoing PleuroscopyCompletedNCT03597828
- Malignant Pleural Effusion: Pleur-X vs. Chemical Pleurodesis in VATSStatus unknownNCT03518788Not applicable